Patient Medication Information: uses, side effects, how to take - Acet 120
What is ACET 120 / ACET 160 / ACET 325 / ACET 650 used for?
ACET 120 / ACET 160 / ACET 325 / ACET 650 suppositories are used to relieve mild to moderate pain, and to reduce fever.
How does ACET work?
It is not completely understood how acetaminophen works in your body. Some explanations involve chemical messengers of inflammation and pain. Other explanations involve aspects of the way nerves interact (neurotransmission) in the brain and spinal cord.
Serious Warnings and Precautions
Liver warning: Acetaminophen may cause severe or possibly fatal liver damage:
Symptoms of liver damage may include:
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What are the ingredients in ACET 120 / ACET 160 / ACET 325 / ACET 650?
Medicinal ingredients: Acetaminophen
Non-medicinal ingredients: Novata (vegetable source triglycerides)
ACET 120 / ACET 160 / ACET 325 / ACET 650 comes in the following dosage forms:
Suppositories: 120 mg, 160 mg, 325 mg, 650 mg
Do not use ACET 120 / ACET 160 / ACET 325 / ACET 650 if:
- You are allergic or hypersensitive to acetaminophen or any other ingredient in this product.
- You are taking other drugs containing acetaminophen. (If you are not sure whether a drug contains acetaminophen, ask your healthcare professional.)
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take ACET 120 / ACET 160 / ACET 325 / ACET 650. Talk about any health conditions or problems you may have, including if you:
- have liver disease
- have kidney disease
- take blood thinning drugs such as warfarin
are pregnant or breastfeeding
Other warnings you should know about:
Stop using ACET 120 / ACET 160 / ACET 325 / ACET 650 and contact your healthcare professional if:
- you develop a severe allergic reaction (difficulty in breathing, skin rash and itching, swelling of the face and throat, runny nose)
- your pain lasts for more than 5 days
- your fever lasts for more than 3 days
Acetaminophen may cause serious skin reactions. Symptoms may include skin reddening, blisters and rash
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with ACET 120 / ACET 160 / ACET 325 / ACET 650:
- Anticoagulants to thin your blood such as warfarin and coumarin
- Anti-inflammatory drugs, nonsteroidal drugs (NSAIDs) or aspirin or other salicylates
- Diflusinal
- Zidovudine
How to take ACET 120 / ACET 160 / ACET 325 / ACET 650:
- Wash hands with soap and water
- Remove plastic wrapper
- Moisten suppository with cool water
- Lie on side with bottom leg straight and upper leg bent up toward chest
- Gently push suppository as high as possible into rectum
- Do not use immediately before bowel movement
- Wash hands with soap and water
Usual dose (children aged 1 to 12):
Use ACET 120, ACET 160 or ACET 325 according to the dose chart below:
| Age (Years) | Single Dose | Maximum Daily Dose | ||
| Under 1 | Use only on the advice of a physician. | |||
| 1 to 2 | 1 ACET 120 suppository (120 mg) every 4 hours | 5 suppositories | ||
| 2 to 4 | 1 ACET 160 suppository (160 mg) every 4 hours | 6 suppositories | ||
| 4 to 6 | 1 ACET 325 suppository (325 mg) every 6 hours | 4 suppositories | ||
| 6 to 12 | 1 ACET 325 suppository (325 mg) every 4 hours | 6 suppositories | ||
Usual dose (adults and children over 12 years):
Use ACET 650 according to the dose chart below:
| Adults and Children over 12 years | Single Dose | Maximum Daily Dose | ||
| 1 ACET 650 suppository (650 mg) every 4 to 6 hours | 6 suppositories | |||
Overdose:
| If you think you, or a person you are caring for, have taken too much ACET 120 / ACET 160 / ACET 325 / ACET 650, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms. |
- Signs of overdose: nausea or vomiting, stomach cramps or pain, and unusual increases in sweating, diarrhea, loss of appetite. Onset may be delayed 24 hours after intake.
- If emergency help is not available: vomiting should be induced at once (within 30 minutes) by ipecac syrup. Vomiting should never be induced in unconscious individuals or in children younger than 1 year old without medical help.
Missed Dose:
If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, do not take the missed dose and just carry on as before. Do not take a double dose to make up for a forgotten dose.
What are possible side effects from using ACET 120 / ACET 160 / ACET 325 / ACET 650?
These are not all the possible side effects you may have when taking ACET 120 / ACET 160 / ACET 325 / ACET 650. If you experience any side effects not listed here, tell your healthcare professional.
Side effects may include:
- Unexplained sore throat and fever
- Unusual tiredness or weakness
- Skin rash, hives, or itching
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
|---|---|---|---|
| Only if severe | In all cases | ||
| RARE | |||
| Allergic reaction (symptoms like swelling of the face, lip or throat, red and lumpy skin, rash, itchiness, hives, difficulty breathing or wheezing) | √ | ||
| Serious skin reactions (skin reddening, blisters, and rash) | √ | ||
| Hepatitis (yellow eyes or skin) | √ | ||
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help |
|---|
| Only if severe | In all cases | ||
|---|---|---|---|
| Renal colic (pain, severe and / or sharp, in lower back and / or side) | √ | ||
| Renal failure (sudden decrease in amount of urine) | √ | ||
| Sterile pyuria (cloudy urine) | √ | ||
| Thrombocytopenia (unusual bleeding or bruising; black, tarry stools; blood in urine or stools; pinpoint red spots on skin) | √ | ||
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
- Store between 15°C and 25°C.
- Keep out of reach and sight or children.
If you want more information about ACET 120 / ACET 160 / ACET 325 / ACET 650:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html; or by calling 1-888-550-6060.