Advil Liqui-Gels: Uses, Side Effects and Dosage

Serious Warnings and Precautions

• Caution in those with heart failure, high blood pressure or other conditions that may cause excess fluid collecting in tissues.
• Caution in patients prone to gastrointestinal tract irritation, including those with a history of peptic ulcer. The chance of stomach bleeding is higher if you are: age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinner or steroid drug, take with other drugs containing an NSAID like acetylsalicylic acid (ASA), ibuprofen, naproxen, or prescription anti-inflammatory drugs, have 3 or more alcoholic drinks every day while using this product.
• Caution in patients at risk of kidney problems, including the elderly or those using diuretics.
• Stop use and contact a doctor if you observe blood in the urine or you develop urgent, frequent, painful or difficult urination.

• Advil Liqui-Gels should not be used during third trimester of pregnancy.

• Talk to your doctor if you are trying to conceive, in your first or second trimester of pregnancy or if breastfeeding.

What is Advil Liqui-Gels used for?

• Temporary relief of mild to moderate migraine headaches including associated symptoms of nausea, and sensitivity to light and sound.
• Fast and effective temporary relief of muscle aches and pain, joint and body pain, backache, muscle sprains and strains, pain of inflammation associated with conditions including arthritis and physical or athletic overexertion (e.g. sprains or strains), headache including tension headache, dental pain, menstrual pain, aches and pain due to the common cold and flu and for reduction of fever.

How does Advil Liqui-Gels work?

Advil Liqui-Gels (Ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID) that can reduce the chemicals produced by your body which cause pain and inflammation.

What are the ingredients in Advil Liqui-Gels?

Medicinal ingredients: Ibuprofen (present as free acid and potassium salt).

Non-medicinal ingredients: FD&C green no. 3, gelatin, lecithin (soy), medium chain triglycerides, pharmaceutical ink, polyethylene glycol, potassium hydroxide, purified water, sorbitan, sorbitol.

Advil Liqui-Gels comes in the following dosage forms: Ibuprofen 200 mg capsules

Do not use Advil Liqui-Gels if:

You have or are:

• active or recurrent stomach ulcer, gastrointestinal (GI) bleeding, or active inflammatory bowel disease (e.g. Crohn’s, colitis),
• taking acetylsalicylic acid (ASA) or any NSAIDs including any other ibuprofen product,
• allergic/hypersensitive to ASA, ibuprofen, other salicylates, other NSAIDs or any of Advil Liqui-Gels ingredients (Refer to the nonmedicinal ingredients on outer carton or composition section),
• nasal polyps (swelling of the inside of the nose), or allergic manifestations such as asthma, anaphylaxis (sudden severe life threatening allergic reaction), urticaria/hives, rhinitis (stuffed or runny nose that may be due to allergies), skin rash or other allergic symptoms,
• dehydrated (significant fluid loss) due to vomiting, diarrhea or lack of fluid intake,
• diagnosed with severe high blood pressure or have severe coronary artery disease,
• right before or after heart surgery,
• serious liver or kidney disease,
• high potassium in the blood,
• Systemic Lupus Erythematosus,
• in your third trimester of pregnancy.

Advil Liqui-Gels should NOT be used in patients under 12 years of age since the safety and effectiveness have NOT been established. Children under 12 should use Children’s Advil®.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you use Advil Liqui-Gels. Talk about any health conditions or problems you may have, including if you:

• you have previous or current stomach ulcers, diabetes, high blood pressure, heart failure, heart disease or thyroid disease, asthma, kidney or liver disease, glaucoma, blood clotting disorder (such as hemophilia), any other serious disease,
• are under doctor’s care for any serious condition,
• are trying to conceive, pregnant or breastfeeding,
• are taking any other drug including over the counter drugs.

Use with caution in the elderly.

Long-term continuous use may increase the risk of heart attack or stroke.

The use of NSAIDs, like Advil Liqui-Gels, in the second trimester of pregnancy should be restricted to the lowest dose necessary for the shortest possible duration.

At 20 weeks or later in pregnancy, your use of NSAIDs may need to be monitored by a doctor due to the rare risk of kidney problems in the unborn baby which may result in decreased amniotic fluid volume and other complications.

Other warnings you should know about:

When using this product:

• take with food or milk if upset stomach occurs

• the risk of heart attack or stroke may increase if you use more than directed or for longer than directed.

Stop use and ask a doctor if

• you show signs of stomach bleeding (see Serious Warnings and Precautions, Stomach bleeding warning)
• pain worsens or lasts more than 5 days
• fever gets worse or lasts more than 3 days
• any new symptoms appear

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

Do not use Advil Liqui-Gels if you are taking:

• Daily low dose ASA (81 – 325 mg), without talking to a doctor or pharmacist. Ibuprofen may interfere with the preventive benefits of ASA.
• ASA or other anti-inflammatory medication.

The following may interact with Advil Liqui-Gels (NOT a complete list):

• acetaminophen,
• anticoagulants (blood thinners),
• digoxin,
• oral antidiabetic agents and insulin,
• diuretics,
• methotrexate,
• lithium,
• protein-bound drugs including probenecid,
• thyroxine,
• antibiotics,
• cyclosporine,
• phenytoin,
• corticosteroids or benzodiazepines,
• other NSAIDs,
• medications for high blood pressure.

Tell your doctor or pharmacist what prescription drugs you are taking or plan to take.

How to take Advil Liqui-Gels:

Take the lowest dose of this medication for the shortest time period. Taking too much Advil® Liqui-Gels may increase your chances of unwanted and sometimes dangerous side effects, especially if you are elderly, have other diseases or take other medications.

Usual dose:

For migraine headaches: Adults and children 12 years and over: Take 1 (every 4 hours) or 2 (every 6-8 hours) Liqui-gels at the first sign of symptoms as needed. Do not exceed 6 Liqui-gels in 24 hours, unless directed by a doctor.

For all other uses: Adults and children 12 years and over: Take 1 (every 4 hours) or 2 (every 6-8 hours) Liqui-gels as needed. Do not exceed 6 Liqui-gels in 24 hours, unless directed by a doctor.

Do not use longer than 3 days for a fever or 5 days for pain relief. Do not give to children under 12. Children under 12 should use Children’s Advil^®.

Overdose:

Missed Dose:

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take your medicine and skip the missed dose. Do not take two doses at the same time.

What are possible side effects from using Advil Liqui-Gels?

These are not all the possible side effects you may have when taking Advil Liqui-Gels. If you experience any side effects not listed here, tell your healthcare professional.

If you think you, or a person you are caring for, have taken too much Advil Liqui-Gels, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms.

Serious side effects and what to do about them

Advil Liqui-Gels may occasionally produce unwanted sides effects such as heartburn, nausea or vomiting, bloating, diarrhea or constipation, nervousness, sleeplessness or itching. Stop use and contact a healthcare professional if these symptoms worsen or persist.

Side effects may be minimized by using the smallest dose for the shortest duration of time.

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Storage:

Store at room temperature (15°-30°C). Protect from light.

Keep out of reach and sight of children. This package contains enough medicine to seriously harm a child. Advil Liqui-Gels 32s is available with child resistant cap.

If you want more information about Advil Liqui-Gels:

• Talk to your healthcare professional
• Find the full product monograph that is prepared for health professionals and includes this Patient Mediation Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); the manufacturers website www.advil.ca, or by calling 1-888-275-9938.

Liqui-Gels® is a trademark or registered trademark of Catalent Pharma Solutions.

Date of Authorization: Aug 14, 2025

Reporting Side Effects

You can report any suspected side effects associated with the use of health products to Health Canada by:

• Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada.html) for information on how to report online, by mail or by fax; or
• Calling toll-free at 1-866-234-2345.

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.

PATIENT MEDICATION INFORMATION

READ THIS FOR SAFE AND EFFECTIVE USE OF YOUR MEDICATION

Advil Extra Strength LIQUI-GELS®

Ibuprofen Capsules, 400 mg (as free acid and potassium salt)

Read this carefully before you start taking Advil Extra Strength LIQUI-GELS and each time you get a refill. This leaflet is a summary and will not tell you everything about this drug. Talk to your healthcare professional about your medical condition and treatment and ask if there is any new information about Advil Extra Strength Liqui-Gels.

What is Advil Extra Strength Liqui-Gels used for:

• Temporary relief of mild to moderate migraine headaches including associated symptoms of nausea, and sensitivity to light and sound.

• Fast and effective temporary relief of muscle aches and pain, joint and body pain, backache, muscle sprains and strains, pain of inflammation associated with conditions including arthritis and physical or athletic overexertion (e.g. sprains or strains), headache including tension headache, dental pain, menstrual pain, aches and pain due to the common cold and flu and for reduction of fever.

  Clinical studies show long lasting pain relief for up to 8 hours.

Serious Warnings and Precautions

• Caution in those with heart failure, high blood pressure or other conditions that may cause excess fluid collecting in tissues.
• Caution in patients prone to gastrointestinal tract irritation, including those with a history of peptic ulcer. The chance of stomach bleeding is higher if you are: age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinner or steroid drug, take with other drugs containing an NSAID like acetylsalicylic acid (ASA), ibuprofen, naproxen, or prescription anti-inflammatory drugs, have 3 or more alcoholic drinks every day while using this product.
• Caution in patients at risk of kidney problems, including the elderly or those using diuretics.
• Stop use and contact a doctor if you observe blood in the urine or you develop urgent, frequent, painful or difficult urination.
• Advil Liqui-Gels should not be used during third trimester of pregnancy.
• Talk to your doctor if you are trying to conceive, in your first or second trimester of pregnancy or if breastfeeding.

How does Advil Extra Strength Liqui-Gels work?

Advil Extra Strength Liqui-Gels (Ibuprofen) is a nonsteroidal anti-inflammatory drug (NSAID) that can reduce the chemicals produced by your body which cause pain and inflammation.

What are the ingredients in Advil Extra Strength Liqui-Gels:

Medicinal Ingredients: Ibuprofen

Non-medicinal ingredients: Gelatin, lecithin (soy), medium chain triglycerides, pharmaceutical ink, polyethylene glycol, potassium hydroxide, purified water, sorbitan, sorbitol.

Advil Extra Strength Liqui-Gels comes in the following dosage forms:

Ibuprofen 400 mg capsules

Do not use Advil Extra Strength Liqui-Gels if

You have or are:

• active or recurrent stomach ulcer, gastrointestinal (GI) bleeding, or active inflammatory bowel disease (e.g. Crohn’s, colitis),
• taking acetylsalicylic acid (ASA) or any other NSAIDs including any other ibuprofen product,
• allergic/hypersensitive to ASA, ibuprofen, other salicylates, other NSAIDs or any of Advil Extra Strength Liqui-Gels ingredients (Refer to the nonmedicinal ingredients on outer carton or composition section),
• nasal polyps (swelling of the inside of the nose), or allergic manifestations such as asthma, anaphylaxis (sudden severe life threatening allergic reaction), urticaria/hives, rhinitis (stuffed or runny nose that may be due to allergies), skin rash or other allergic symptoms,
• dehydrated (significant fluid loss) due to vomiting, diarrhea or lack of fluid intake,
• diagnosed with severe high blood pressure or have severe coronary artery disease,
• right before or after heart surgery,
• serious liver or kidney disease,
• high potassium in the blood,
• Systemic Lupus Erythematosus,
• in your third trimester of pregnancy.

Advil Extra Strength Liqui-Gels should NOT be used in patients under 12 years of age since the safety and effectiveness have NOT been established. Children under 12 should use Children’s Advil®.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Advil Extra Strength Liqui-Gels. Talk about any health conditions or problems you may have, including if you:

• have previous or current stomach ulcers, diabetes, high blood pressure, heart failure, heart disease or thyroid disease, asthma, kidney or liver disease, glaucoma, blood clotting disorder (such as hemophilia), any other serious disease,
• are under doctor’s care for any serious condition,
• are trying to conceive, pregnant or breastfeeding
• are taking any other drug including over the counter drugs.

Use with caution in the elderly.

Long-term continuous use may increase the risk of heart attack or stroke.

The use of NSAIDs, like Advil Extra Strength Liqui-Gels, in the second trimester of pregnancy should be restricted to the lowest dose necessary for the shortest possible duration.

At 20 weeks or later in pregnancy, your use of NSAIDs may need to be monitored by a doctor due to the rare risk of kidney problems in the unborn baby which may result in decreased amniotic fluid volume and other complications.

Other warnings you should know about:

When using this product:

• take with food or milk if upset stomach occurs
• the risk of heart attack or stroke may increase if you use more than directed or for longer than directed.

Stop use and ask a doctor if

• you show signs of stomach bleeding (see Serious Warnings and Precautions –Stomach bleeding warning)
• pain worsens or lasts more than 5 days
• fever worsens or lasts more than 3 days
• any new symptoms appear

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

Do not use Advil Extra Strength Liqui-Gels if you are taking:

• Daily low dose ASA (81 – 325 mg), without talking to a doctor or pharmacist. Ibuprofen may interfere with the preventive benefits of ASA.
• ASA or other anti-inflammatory medication.

The following may interact with Advil Extra Strength Liqui-Gels (NOT a complete list):

• acetaminophen,
• anticoagulants (blood thinners),
• digoxin,
• oral antidiabetic agents and insulin,
• diuretics,
• methotrexate,
• lithium,
• protein-bound drugs including probenecid,
• thyroxine, antibiotics,
• cyclosporine, phenytoin, corticosteroids or benzodiazepines,
• other NSAIDs, or medications for high blood pressure.

Tell your doctor or pharmacist what prescription drugs you are taking or plan to take.

How to take Advil Extra Strength Liqui-Gel:

Take the lowest dose of this medication for the shortest time period. Taking too much Advil® Extra Strength Ligui-Gels increase your chances of unwanted and sometimes dangerous side effects, especially if you are elderly, have other diseases or take other medications.

Usual dose:

For migraine headaches: Adults and children 12 years and over: Take 1 Extra Strength Liqui-gel at the first sign of symptoms and every 6-8 hours as needed. Do not exceed 3 Liqui-gels in 24 hours, unless directed by a doctor.

For all other uses: Adults and children 12 years and over: Take 1 Extra Strength Liqui-gel every 6-8 hours as needed. Do not exceed 3 Liqui-gels in 24 hours, unless directed by a doctor.

Do not use longer than 3 days for a fever or 5 days for pain relief. Do not give to children under 12. Children under 12 should use Children’s Advil^®.

Overdose:

Missed Dose:

If you think you, or a person you are caring for, have taken too much Advil Extra Strength Liqui-Gels, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take your medicine and skip the missed dose. Do not take two doses at the same time.

What are possible side effects from using Advil Extra Strength Liqui-Gels?

These are not all the possible side effects you may have when taking Advil Capsules. If you experience any side effects not listed here, tell your healthcare professional.

Serious side effects and what to do about them

Advil Extra Strength Liqui-Gels may occasionally produce unwanted sides effects such as heartburn, nausea or vomiting, bloating, diarrhea or constipation, nervousness, sleeplessness or itching. Stop use and contact a healthcare professional if these symptoms worsen or persist.

Side effects may be minimized by using the smallest dose for the shortest duration of time.

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Store at room temperature (15°-30°C). Protect from light.

Keep out of reach and sight of children. This package contains enough medicine to seriously harm a child. Advil Extra Strength Liqui-Gels 24s is available with child resistant cap.

If you want more information about Advil Extra Strength Liqui-Gels:

• Talk to your healthcare professional
• Find the full product monograph that is prepared for health professionals and includes this Patient Mediation Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); the manufacturers website www.advil.ca, or by calling 1-888-275-9938.

Liqui-Gels® is a trademark or registered trademark of Catalent Pharma Solutions.

Date of Authorization: Aug 14, 2025

Reporting Side Effects

You can report any suspected side effects associated with the use of health products to Health Canada by:

• Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada.html) for information on how to report online, by mail or by fax; or
• Calling toll-free at 1-866-234-2345.

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.

PATIENT MEDICATION INFORMATION

READ THIS FOR SAFE AND EFFECTIVE USE OF YOUR MEDICATION

Advil Arthritis Pain

Ibuprofen Capsules, 400mg (as free acid and potassium salt)

Read this carefully before you start taking Advil Arthritis Pain and each time you get a refill. This leaflet is a summary and will not tell you everything about this drug. Talk to your healthcare professional about your medical condition and treatment and ask if there is any new information about Advil Arthritis Pain.

What is Advil Arthritis Pain used for:

• Arthritis Pain: Temporary relief of pain of inflammation associated with conditions of arthritis.

• Also used for fast and effective temporary relief of mild to moderate migraine headaches, muscle aches and pain, joint and body pain, backache, muscle sprains and strains, pain of inflammation associated with physical or athletic overexertion (e.g. sprains or strains), headache including tension headache, dental pain, menstrual pain, aches and pain due to the common cold and flu and for reduction of fever.

  Clinical studies show long lasting pain relief for up to 8 hours.

How does Advil Arthritis Pain work?

Serious Warnings and Precautions

• Caution in those with heart failure, high blood pressure or other conditions that may cause excess fluid collecting in tissues.
• Caution in patients prone to gastrointestinal tract irritation, including those with a history of peptic ulcer. The chance of stomach bleeding is higher if you are: age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinner or steroid drug, take with other drugs containing an NSAID like acetylsalicylic acid (ASA), ibuprofen, naproxen, or prescription anti-inflammatory drugs, have 3 or more alcoholic drinks every day while using this product.
• Caution in patients at risk of kidney problems, including the elderly or those using diuretics.
• Stop use and contact a doctor if you observe blood in the urine or you develop urgent, frequent, painful or difficult urination.
• Advil Liqui-Gels should not be used during third trimester of pregnancy.
• Talk to your doctor if you are trying to conceive, in your first or second trimester of pregnancy or if breastfeeding.

Advil Arthritis Pain (Ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID) that can reduce the chemicals produced by your body which cause pain and inflammation.

What the ingredients in Advil Arthritis Pain:

Medicinal ingredient: Ibuprofen (present as free acid and potassium salt).

Non-medicinal ingredients: D&C Yellow No. 10, FD&C Green No. 3, FD&C Red No. 40, gelatin, lecithin (soy), medium chain triglycerides, pharmaceutical ink, polyethylene glycol, potassium hydroxide, purified water, sorbitan, sorbitol.

What dosage forms it comes in:

Ibuprofen 400 mg capsules

Do not use Advil Arthritis Pain if:

You have or are:

• active or recurrent stomach ulcer, gastrointestinal (GI) bleeding, or active inflammatory bowel disease (e.g. Crohn’s, colitis),
• taking acetylsalicylic acid (ASA) or any other NSAIDs including any other ibuprofen product,
• allergic/hypersensitive to ASA, ibuprofen, other salicylates, other NSAIDs or any of Advil Arthritis Pain ingredients (Refer to the nonmedicinal ingredients on outer carton or composition section),
• nasal polyps (swelling of the inside of the nose), or allergic manifestations such as asthma, anaphylaxis (sudden severe life threatening allergic reaction), urticaria/hives, rhinitis (stuffed or runny nose that may be due to allergies), skin rash or other allergic symptoms,
• dehydrated (significant fluid loss) due to vomiting, diarrhea or lack of fluid intake,
• diagnosed with severe high blood pressure or have severe coronary artery disease,
• right before or after heart surgery,
• serious liver or kidney disease,
• high potassium in the blood,
• Systemic Lupus Erythematosus,
• in your third trimester of pregnancy.

Advil Arthritis Pain should NOT be used in patients under 12 years of age since the safety and effectiveness have NOT been established. Children under 12 should use Children’s Advil®.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Advil Arthritis Pain. Talk about any health conditions or problems you may have, including if you:

• have previous or current stomach ulcers, diabetes, high blood pressure, heart failure, heart disease or thyroid disease, asthma, kidney or liver disease,

  • glaucoma, blood clotting disorder (such as hemophilia), any other serious disease,
• are under doctor’s care for any serious condition,
• are trying to conceive, pregnant or breastfeeding
• are taking any other drug including over the counter drugs.

Use with caution in the elderly.

Long-term continuous use may increase the risk of heart attack or stroke.

The use of NSAIDs, like Advil Arthritis Pain, in the second trimester of pregnancy should be restricted to the lowest dose necessary for the shortest possible duration.

At 20 weeks or later in pregnancy, your use of NSAIDs may need to be monitored by a doctor due to the rare risk of kidney problems in the unborn baby which may result in decreased amniotic fluid volume and other complications.

Other warnings you should know about:

When using this product:

• take with food or milk if upset stomach occurs
• the risk of heart attack or stroke may increase if you use more than directed or for longer than directed.

Stop use and ask a doctor if:

• you show signs of stomach bleeding (see Serious Warnings and Precautions, Stomach bleeding warning)
• pain worsens or lasts more than 5 days
• fever worsens or lasts more than 3 days
• any new symptoms appear

The following may interact with Advil Arthritis Pain (NOT a complete list):

• acetaminophen,
• anticoagulants (blood thinners),
• digoxin,
• oral antidiabetic agents and insulin,
• diuretics,
• methotrexate,
• lithium,
• protein-bound drugs including probenecid,
• thyroxine,
• antibiotics,
• cyclosporine,
• phenytoin,
• corticosteroids or benzodiazepines,
• other NSAIDs,
• medications for high blood pressure.

Tell your doctor or pharmacist what prescription drugs you are taking or plan to take.

How to take Advil Arthritis Pain:

Take the lowest dose of this medication for the shortest time period. Taking too much Advil Arthritis Pain may increase your chances of unwanted and sometimes dangerous side effects, especially if you are elderly, have other diseases or take other medications.

Usual dose:

Adults and children 12 years and over: Take 1 Liqui-gel every 6-8 hours as needed. Do not exceed 3 Liqui-gels in 24 hours, unless directed by a doctor.

Do not use longer than 3 days for a fever or 5 days for pain relief. Do not give to children under 12.

Overdose:

Missed Dose:

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take your medicine and skip the missed dose. Do not take two doses at the same time.

What are possible side effects from using Advil Arthritis Pain?

These are not all the possible side effects you may have when taking Advil Arthritis Pain. If you experience any side effects not listed here, tell your healthcare professional.

Serious side effects and what to do about them

If you think you, or a person you are caring for, have taken too much Advil Arthritis Pain, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms.

Advil Arthritis Pain may occasionally produce unwanted sides effects such as heartburn, nausea or vomiting, bloating, diarrhea or constipation, nervousness, sleeplessness or itching. Stop use and contact a healthcare professional if these symptoms worsen or persist.

Side effects may be minimized by using the smallest dose for the shortest duration of time.

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Reporting Side Effects

You can report any suspected side effects associated with the use of health products to Health Canada by:

• Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada.html) for information on how to report online, by mail or by fax; or
• Calling toll-free at 1-866-234-2345.

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.

Storage:

Store at room temperature (15°-30°C). Protect from light.

Keep out of reach and sight of children. This package contains enough medicine to seriously harm a child. Advil Arthritis Pain is not child-resistant.

If you want more information about Advil Arthritis Pain:

• Talk to your healthcare professional
• Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html; the manufacturer’s website www.advil.ca, or by calling 1-888-275-9938.

Liqui-Gels® is a trademark or registered trademark of Catalent Pharma Solutions.

Date of Authorization: Aug 14, 2025

PATIENT MEDICATION INFORMATION

READ THIS FOR SAFE AND EFFECTIVE USE OF YOUR MEDICATION

ADVIL MIGRAINE & HEADACHE

Ibuprofen Capsules, 400mg (as free acid and potassium salt)

Read this carefully before you start taking Advil Migraine & Headache and each time you get a refill. This leaflet is a summary and will not tell you everything about this drug. Talk to your healthcare professional about your medical condition and treatment and ask if there is any new information about Advil Migraine & Headache.

What is Advil Migraine & Headache used for?

• Migraine: Fast and effective temporary relief of mild to moderate migraine headaches including associated symptoms of nausea, and sensitivity to light and sound.
• Also used for fast and effective temporary relief of muscle aches and pain, joint and body pain, backache, muscle sprains and strains, pain of inflammation associated with conditions including arthritis and physical or athletic overexertion (e.g. sprains or strains), headache including tension headache, dental pain, menstrual pain, aches and pain due to the common cold and flu and for reduction of fever.

Serious Warnings and Precautions

• Caution in those with heart failure, high blood pressure or other conditions that may cause excess fluid collecting in tissues.
• Caution in patients prone to gastrointestinal tract irritation, including those with a history of peptic ulcer. The chance of stomach bleeding is higher if you are: age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinner or steroid drug, take with other drugs containing an NSAID like acetylsalicylic acid (ASA), ibuprofen, naproxen, or prescription anti-inflammatory drugs, have 3 or more alcoholic drinks every day while using this product.
• Caution in patients at risk of kidney problems, including the elderly or those using diuretics.
• Stop use and contact a doctor if you observe blood in the urine or you develop urgent, frequent, painful or difficult urination.
• Advil Migraine & Headache should not be used during third trimester of pregnancy.
• Talk to your doctor if you are trying to conceive, in your first or second trimester of pregnancy or if breastfeeding.

Clinical studies show long lasting pain relief for up to 8 hours.

How does Advil Migraine & Headache work?

Advil Arthritis Pain is a non-steroidal anti-inflammatory drug (NSAID) that can reduce the chemicals produced by your body which cause pain and inflammation.

What are the ingredients in Advil Migraine & Headache?

Medicinal ingredient: Ibuprofen (present as free acid and potassium salt).

Non-medicinal ingredients: D&C Yellow No. 10, FD&C Green No. 3, FD&C Red No. 40, gelatin, lecithin (soy), medium chain triglycerides, pharmaceutical ink, polyethylene glycol, potassium hydroxide, purified water, sorbitan, sorbitol.

Advil Migraine & Headache comes in the following dosage forms: Ibuprofen 400 mg capsules.

Do not use Advil Migraine & Headache if:

You have or are

• active or recurrent stomach ulcer, gastrointestinal (GI) bleeding, or active inflammatory bowel disease (e.g. Crohn’s, colitis),
• taking acetylsalicylic acid (ASA) or any NSAIDs including any other ibuprofen product,
• allergic/hypersensitive to ASA, ibuprofen, other salicylates, other NSAIDs or any of Advil Liqui-Gels ingredients (Refer to the nonmedicinal ingredients on outer carton or composition section),
• nasal polyps (swelling of the inside of the nose), or allergic manifestations such as asthma, anaphylaxis (sudden severe life threatening allergic reaction), urticaria/hives, rhinitis (stuffed or runny nose that may be due to allergies), skin rash or other allergic symptoms,
• dehydrated (significant fluid loss) due to vomiting, diarrhea or lack of fluid intake,
• diagnosed with severe high blood pressure or have severe coronary artery disease,
• right before or after heart surgery,
• serious liver or kidney disease,
• high potassium in the blood,
• Systemic Lupus Erythematosus,
• in your third trimester of pregnancy.

Advil Migraine & Headache should NOT be used in patients under 12 years of age since the safety and effectiveness have NOT been established. Children under 12 should use Children’s Advil®.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Advil Migraine & Headache. Talk about any health conditions or problems you may have, including if you:

• have previous or current stomach ulcers, diabetes, high blood pressure, heart failure, heart disease or thyroid disease, asthma, kidney or liver disease, glaucoma, blood clotting disorder (such as hemophilia), any other serious disease,
• are under doctor’s care for any serious condition,
• are trying to conceive, pregnant or breastfeeding,
• are taking any other drug including over the counter drugs.

Use with caution in the elderly.

Long-term continuous use may increase the risk of heart attack or stroke.

The use of NSAIDs, like Advil Migraine & Headache, in the second trimester of pregnancy should be restricted to the lowest dose necessary for the shortest possible duration.

At 20 weeks or later in pregnancy, your use of NSAIDs may need to be monitored by a doctor due to the rare risk of kidney problems in the unborn baby which may result in decreased amniotic fluid volume and other complications.

Other warnings you should know about:

When using this product:

• take with food or milk if upset stomach occurs
• the risk of heart attack or stroke may increase if you use more than directed or for longer than directed.

Stop use and ask a doctor if:

• you show signs of stomach bleeding (see Serious Warnings and Precautions, Stomach bleeding warning)
• pain worsens or lasts more than 5 days
• fever gets worse or lasts more than 3 days
• any new symptoms appear.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

The following may interact with Advil Migraine & Headache (NOT a complete list):

• acetaminophen
• anticoagulants (blood thinners)
• digoxin
• oral antidiabetic agents and insulin
• diuretics
• methotrexate
• lithium
• protein-bound drugs including probenecid
• thyroxine
• antibiotics
• cyclosporine
• phenytoin
• corticosteroids or benzodiazepines
• other NSAIDs
• medications for high blood pressure

Tell your doctor or pharmacist what prescription drugs you are taking or plan to take.

How to take Advil Migraine & Headache:

Take the lowest dose of this medication for the shortest time period. Taking too much Advil Arthritis Pain may increase your chances of unwanted and sometimes dangerous side effects, especially if you are elderly, have other diseases or take other medications.

Usual dose:

For migraine headaches: Adults and children 12 years and over: Take 1 Advil Migraine & Headache liqui-gel at the first sign of symptoms and every 6-8 hours as needed. Do not exceed 3 Liqui-gels in 24 hours, unless directed by a doctor.

For all other uses: Adults and children 12 years and over: Take 1 Advil Migraine & Headache liqui-gel every 6-8 hours as needed. Do not exceed 3 Liqui-gels in 24 hours, unless directed by a doctor.

Do not use longer than 3 days for a fever or 5 days for pain relief. Do not give to children under 12. Children under 12 should use Children’s Advil^®.

Overdose:

Missed Dose:

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take your medicine and skip the missed dose. Do not take two doses at the same time.

If you think you, or a person you are caring for, have taken too much Advil Advil Migraine & Headache, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms.

What are possible side effects from using Advil Migraine & Headache?

These are not all the possible side effects you may have when taking Advil Migraine & Headache. If you experience any side effects not listed here, tell your healthcare professional.

Serious side effects and what to do about them

Advil Migraine & Headache may occasionally produce unwanted sides effects such as heartburn, nausea or vomiting, bloating, diarrhea or constipation, nervousness, sleeplessness or itching. Stop use and contact a healthcare professional if these symptoms worsen or persist.

Side effects may be minimized by using the smallest dose for the shortest duration of time.

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Storage:

Store at room temperature (15°-30°C). Protect from light.

Keep out of reach and sight of children. This package contains enough medicine to seriously harm a child. Advil Migraine & Headache is not child-resistant.

If you want more information about Advil Migraine & Headache:

• Talk to your healthcare professional
• Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html; the manufacturer’s website www.advil.ca, or by calling 1-888-275-9938.

Liqui-Gels® is a trademark or registered trademark of Catalent Pharma Solutions.

Date of Authorization: Aug 14, 2025

Reporting Side Effects

You can report any suspected side effects associated with the use of health products to Health Canada by:

• Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada.html) for information on how to report online, by mail or by fax; or
• Calling toll-free at 1-866-234-2345.

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.