Jamp Citalopram Tablets: Uses, Side Effects and Dosage

Serious Warnings and Precautions

What is JAMP Citalopram Tablets used for?

JAMP Citalopram Tablets is used to relieve the symptoms of depression in adults. Your healthcare professional will keep evaluating if JAMP Citalopram Tablets is still safe and effective for you if you take it for a long time.

How does JAMP Citalopram Tablets work?

Citalopram is known as an antidepressant and belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs).

JAMP Citalopram Tablets works by increasing the levels of a chemical in the brain called serotonin.

What are the ingredients in JAMP Citalopram Tablets?

Medicinal ingredients: Citalopram hydrobromide.

Non-medicinal ingredients: Crospovidone, lactose monohydrate, microcrystalline cellulose, magnesium stearate, povidone, and starch - maize. The film coating contains hypromellose, macrogol, and titanium dioxide.

JAMP Citalopram Tablets comes in the following dosage forms:

30 mg tablets

Do not use JAMP Citalopram Tablets if:

• you are allergic to citalopram hydrobromide.
• you are allergic to any of the other ingredients in JAMP Citalopram Tablets or to a component of the container.
• you are also taking the medicine pimozide, used to treat schizophrenia.
• you are currently taking or have taken within 14 days medicines called monoamine oxidase antidepressants such as phenelzine sulphate, tranylcypromine or moclobemide, or other monoamine oxidase inhibitors such as linezolid, methylene blue, selegiline.
• you have been told that you have QT interval prolongation (abnormal electrical activity of the heart) or have been diagnosed with a condition called a congenital long QT syndrome.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take JAMP Citalopram Tablets. Talk about any health conditions or problems you may have, including if you:

• have heart problems.
• have diabetes. JAMP Citalopram Tablets may make it more difficult to control your blood sugar.
• have liver or kidney problems.
• have or have had a seizure disorder.
• have or have had manic episodes or have been diagnosed with bipolar disorder.
• are receiving electroconvulsive therapy.
• have a bleeding disorder or have been told that you have low platelets.
• have a family history of QT / QTc prolongation (abnormal electrical activity of the heart).
• have electrolyte disturbances like low blood potassium, magnesium, or calcium levels or conditions that could lead to this such as vomiting, diarrhea, dehydration.
• had a recent bone fracture or were told you have osteoporosis or risk factors for osteoporosis.
• are taking other antidepressants, triptans used to treat migraines, lithium, opioids (including to treat pain, or drug dependence), or drugs containing tryptophan.
• have habits of alcohol and / or street drug consumption.
• are taking St. John’s Wort, an herbal product used to treat depression

Other warnings you should know about:

• It is important that you and your healthcare professional talk regularly about how you are feeling while you are taking JAMP Citalopram Tablets.

• JAMP Citalopram Tablets should not be used in children and adolescents under 18 years of age or in patients aged 65 or older.

Activation of Mania: Tell your healthcare professional if you have or have had manic episodes in the past or if you have been diagnosed with bipolar disorder. JAMP Citalopram Tablets should be used with caution if you have a history of manic episodes. Some patients with bipolar disorder (also known as manic depression) may enter into a manic phase when they start taking JAMP Citalopram Tablets. Tell your healthcare professional if you experience symptoms of mania such as excessive physical activity, overactive behaviour or thoughts, increased energy, trouble sleeping, racing thoughts, reckless behaviour, excessive happiness or irritability, talking more or faster than usual.

Bleeding Problems: Before taking JAMP Citalopram Tablets tell your healthcare professional if you have a bleeding disorder including low blood platelets. Drugs from the class citalopram belongs to may increase the chance of a bleeding event such as nose bleeds, bruising and even life-threatening bleeding. This is more likely if you have a history of a bleeding disorder or are taking other drugs that are known to affect blood clotting. Talk to your healthcare professional about drugs that might increase bleeding.

Pregnancy: Before taking JAMP Citalopram Tablets, tell your healthcare professional if you are pregnant, think you might be pregnant or are planning to become pregnant. You should not take JAMP Citalopram Tablets if you are pregnant unless you and your healthcare professional have discussed the risks and decided that you should. Tell your healthcare professional right away if you become pregnant while taking JAMP Citalopram Tablets. If you take JAMP Citalopram Tablets near the end of your pregnancy, you could have heavy vaginal bleeding shortly after giving birth.

Effects on Newborns: Some newborn babies whose mothers took medications such as citalopram during pregnancy have developed problems at birth. These problems include prolonged hospitalization, breathing support and tube feeding.

Symptoms can include:

• feeding and / or breathing difficulties
• bluish skin
• seizures
• body temperature changes
• vomiting
• low blood sugar
• tense or overly relaxed muscles
• vivid reflexes
• tremor
• jitteriness
• irritability
• sleeping difficulties and constant crying.

In most cases, these medications were taken during the third trimester of pregnancy. These symptoms are caused by the medication itself or from the effects of suddenly stopping the medication. These symptoms normally go away over time. However, if your baby experiences any of these symptoms, contact your healthcare professional as soon as you can.

Persistent Pulmonary Hypertension of the Newborn (PPHN): If you take JAMP Citalopram Tablets towards the end of your pregnancy, your newborn may be at risk of having a serious lung condition called Persistent Pulmonary Hypertension of the Newborn (PPHN). This causes breathing problems in newborns soon after birth. Newborn babies may breathe faster and appear bluish. These symptoms usually begin during the first 24 hours after the baby is born. If this happens to your newborn baby, get immediate medical help for them.

Breastfeeding: Tell your healthcare professional if you are breastfeeding or planning to breastfeed. JAMP Citalopram Tablets is released into breast milk. It is not known if this is safe for your baby. You should not breastfeed a baby if you are taking JAMP Citalopram Tablets unless you and your healthcare professional have discussed the risks and decided that you should.

Effect on the electrical activity of the heart: JAMP Citalopram Tablets has an effect on the electrical activity of the heart known as QT / QTc prolongation (abnormal electrical activity of the heart). This can lead to disturbances in heart rhythm (arrhythmias / dysrhythmias) that could result in dizziness, palpitations (sensation of rapid, pounding, or irregular heartbeat), fainting or cardiac arrest and death. This is more likely in patients with risk factors, such as heart disease, heart attack, or in the presence of certain drugs that could interact with the activity of the heart. If you experience any symptoms of a possible heart rhythm disturbance (abnormal heart rate or rhythm), such as dizziness, palpitations (sensation of rapid, pounding, or irregular heartbeat), fainting, or seizures, you should seek immediate medical attention.

Serotonin toxicity (also known as Serotonin syndrome) or Neuroleptic malignant syndrome: JAMP Citalopram Tablets can cause Serotonin toxicity or Neuroleptic malignant syndrome, rare but potentially life-threatening conditions. They can cause serious changes in how your brain, muscles and digestive system work. You may develop Serotonin toxicity or Neuroleptic malignant syndrome if you take JAMP Citalopram Tablets with certain medications used to treat depression, migraine or other mental health problems such as schizophrenia.

Serotonin toxicity or Neuroleptic malignant syndrome symptoms include:

• fever, sweating, shivering, diarrhea, nausea, vomiting;
• muscle shakes, jerks, twitches or stiffness, changes in reflexes, loss of coordination
• fast heartbeat, changes in blood pressure;
• confusion, agitation, restlessness, hallucinations, mood changes, unconsciousness, and coma

Effects on Sexual Function: Taking medicines like JAMP Citalopram Tablets may cause symptoms of sexual dysfunction. In some cases these symptoms have continued after stopping JAMP Citalopram Tablets treatment. Talk to your healthcare professional if you experience symptoms such as a decrease in sexual desire, performance or satisfaction.

Risk of Bone Fractures: Taking JAMP Citalopram Tablets may increase your risk of breaking a bone if you are elderly, have osteoporosis or other risk factors for breaking a bone. You should take extra care to avoid falls especially if you get dizzy or have low blood pressure.

Angle-closure Glaucoma: JAMP Citalopram Tablets can cause dilation of the pupil. This may cause an acute glaucoma attack in an individual with narrow ocular angles. Having your eyes examined before you take JAMP Citalopram Tablets could help identify if you are at risk of having angle-closure glaucoma. Get immediate medical help if you experience:

• eye pain
• changes in vision
• swelling or redness in or around the eye.

Driving and using machines: JAMP Citalopram Tablets may impair your ability to drive or to use machines. Wait until you know how JAMP Citalopram Tablets affects you before driving or using machines. Do not drive or use machines if JAMP Citalopram Tablets impairs your ability to do so safely.

Discontinuation Symptoms: Contact your healthcare professional before stopping or reducing your dosage of JAMP Citalopram Tablets. If you stop or reduce the dosage of JAMP Citalopram Tablets abruptly, or if you miss a dose, you may experience symptoms such as dizziness, sleep disturbances, abnormal dreams, sensory disturbance like electric shock sensations, agitation, anxiety, headache, tremor (shakiness), nausea, vomiting. Tell your healthcare professional immediately if you have these or any other symptoms. Your healthcare professional may adjust the dosage of citalopram by prescribing you another citalopram product to reduce the symptoms.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

The following may interact with JAMP Citalopram Tablets:

• drugs to treat heart rhythm disturbances (antiarrhythmics)
• antipsychotics, used to treat schizophrenia
• opioids (including for pain, drug dependence or anesthesia) such as methadone, buprenorphine, tramadol, fentanyl, tapentadol, meperidine or pentazocine
• drugs to treat infections
• drugs to treat nausea and vomiting
• cancer drugs
• asthma drugs
• diuretics (water pills)
• carbamazepine, used to treat seizures

• other SSRIs (e.g., escitalopram) or any other antidepressant (e.g., imipramine, desipramine)

  Serious Drug Interactions

Do not use JAMP Citalopram Tablets mg if you:

• are taking or have recently taken monoamine oxidase inhibitors such as phenelzine, tranylcypromine, moclobemide or selegiline, linezolid (an antibiotic) or Methylene blue (intravenous)
• are taking pimozide
• lithium, used to treat mood disorder
• tryptophan, for sleep aid or treating anxiety
• cimetidine, for acidity problems
• triptans (e.g., sumatriptan, zolmitriptan, naratriptan), for migraine
• fluconazole, ketoconazole, itraconazole, for treating fungal infections
• erythromycin, used to treat infections
• warfarin, used to prevent blood clots
• omeprazole, used to treat stomach problems
• any herbal product such as St. John’s Wort
• certain medicines which may affect blood clotting and increased bleeding, such as oral anticoagulants (e.g., warfarin, dabigatran), acetylsalicyIic acid (e.g., Aspirin®) and other non-steroidal anti-inflammatory drugs (ibuprofen)
• certain medicines used to treat cough, such as dextromethorphan.

Avoid drinking alcohol while taking JAMP Citalopram Tablets.

How to take JAMP Citalopram Tablets:

• Take JAMP Citalopram Tablets exactly as your healthcare professional has told you.
• Swallow tablets whole with water. Do not chew them.

• You can take JAMP Citalopram Tablets with or without food.

• Take JAMP Citalopram Tablets once a day at the same time every day.
• Continue taking JAMP Citalopram Tablets even if you do not feel better. It may take several weeks for it to work, and improvement may be gradual.
• Keep taking JAMP Citalopram Tablets for as long as your healthcare professional recommends. Do not stop taking JAMP Citalopram Tablets abruptly even if you feel better unless your doctor has told you to.
• Never take more JAMP Citalopram Tablets than your healthcare professional has prescribed for you.
• Follow all instructions given to you by your healthcare professional

Usual dose:

It is important that you take JAMP Citalopram Tablets exactly as directed by your healthcare professional. JAMP Citalopram Tablets is only available at 30 mg and your healthcare professional might prescribe another citalopram product if you are elderly, have liver problems or in other situations.

Overdose:

Missed Dose:

If you forget a dose, take the next dose as planned. Do not take a double dose to make up for a forgotten dose.

What are possible side effects from using JAMP Citalopram Tablets?

These are not all the possible side effects you may have when taking JAMP Citalopram Tablets. If you experience any side effects not listed here, tell your healthcare professional.

Side effects may include:

• Fatigue
• Dry mouth
• Increased sweating
• Tremor (shakiness)
• Nausea
• Diarrhea
• Somnolence (sleepiness)
• Ejaculation disorder

Serious side effects and what to do about them

Serious side effects and what to do about them

Serious side effects and what to do about them

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Reporting Side Effects

Storage:

Store at room temperature 15-30°C in a dry place.

Keep out of reach and sight of children.

If you want more information about JAMP Citalopram Tablets:

• Talk to your healthcare professional

• Find the full Product Monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); or by calling 1-866-399-9091.

  JAMP Pharma Corporation

  1310 rue Nobel

  Boucherville, Quebec

  J4B 5H3, Canada

  Last Prepared: October 17, 2023