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Jamp-Memantine: Uses, Side Effects and Dosage

Updated:
Facts
Status:
Prescription (Rx)
Strength:
5 mg, 10 mg
Active ingredient:
ATC code:
Similar drugs:

Source: Health Canada – Drug Product Database (DPD) and product monographs · About this document

Patient Medication Information: uses, side effects, how to take - Jamp-Memantine

ABOUT THIS MEDICATION

What the medication is used for:

JAMP-Memantine has been prescribed to you, by a doctor to relieve symptoms of Alzheimer’s disease.

What it does:

The brain contains N-methyl-D-aspartate (NMDA) receptors that are involved in transmitting nerve signals and may be important for learning and memory. Abnormal transmission of nerve signals through NMDA-receptors in the brain may affect memory and other mental functions and contribute to symptoms of Alzheimer’s disease. JAMP-Memantine belongs to a group of medicines called NMDA-receptor antagonists. The action of JAMP-Memantine on NMDA-receptors may help normalize the transmission of nerve signals, which may help slow the decline in some of the symptoms of Alzheimer disease. When it should not be used:

  • You should not be taking JAMP-Memantine if you are

    pregnant, unless in the opinion of the doctor, the expected benefit to the patient markedly outweighs the possible hazards to the foetus.

  • You should not be taking JAMP-Memantine if you are

    breast-feeding.

  • Do not take JAMP-Memantine if you are allergic to it, or

    to any of the other ingredients listed in this leaflet (see ‘What the non- medicinal ingredients are’).

  • Stop taking JAMP-Memantine if you experience an

    allergic reaction or any severe side effect.

What the medicinal ingredient is:

memantine hydrochloride

What the nonmedicinal ingredients are:

Colloidal Silicone Dioxide, Croscarmellose Sodium, Macrogol/PEG, Magnesium Stearate, Microcrystalline Cellulose, Polyvinyl Alcohol-Part. Hydrolyzed, Talc, and Titanium Dioxide.

What dosage forms it comes in:

5 mg and 10 mg tablets. The 10 mg tablets can be split.

WARNINGS AND PRECAUTIONS

BEFORE you use JAMP-Memantine talk to your doctor or pharmacist if:

  • You have/had a medical condition, including heart problems, uncontrolled hypertension (high blood pressure), history of seizures or kidney disease
  • You are taking any medications (prescription or non- prescription) or have taken any within the last 14 days.
  • You ever had an allergic reaction to any medication
  • You are pregnant or thinking of becoming pregnant, or if you are breast-feeding.

  • There are conditions which can change the speed at which the body would normally eliminate the drug over time and you should tell your doctor, as JAMP-Memantine dosage may have to be adjusted if:

    • You have recently changed or intend to change your diet substantially (e.g. from normal diet to strict vegetarian diet)

    • You are suffering from renal tubulary acidosis

      (RTA, an excess of acid-forming substances in the blood due to renal dysfunction [kidney problems])

    • You have a urinary tract infection

INTERACTIONS WITH THIS MEDICATION

Drugs that may interact with JAMP-Memantine include:

  • NMDA-receptor antagonists (e.g. amantadine)
  • Cimetidine
  • Ranitidine
  • Procainamide
  • Quinidine
  • Quinine
  • Hydrochlorothiazide (or any combination with hydrochlorothiazide)
  • Anticholinergics (generally used to treat movement disorders or intestinal cramps)
  • L-dopa and dopaminergic agonists (drugs such as bromocriptine, ropinirole, pramipexole)
  • Ketamine
  • Dextromethorphan (found in cough syrup labelled DM)
  • Anticoagulant (blood thinner) medications taken by mouth

PROPER USE OF THIS MEDICATION

Usual dose:

  • It is important that you take JAMP-Memantine exactly as your doctor has instructed.
  • Usually your doctor will prescribe 20 mg per day, which you will take as two separate doses of 10 mg. In order to reduce the risk of side effects this dose will be achieved gradually by the following daily treatment scheme, starting at a dose of 5 mg per day:
IMPORTANT: PLEASE READ
AMPM
Week 11 x 5 mg tabletNone
Week 21 x 5 mg tablet1 x 5 mg tablet
Week 31 x 10 mg tablet1 x 5 mg tablet
Week 4 and beyond1 x 10 mg tablet1 x 10 mg tablet

  • Never change the dose of JAMP-Memantine unless

    your doctor tells you to.

  • Swallow the tablets whole with some water. Do not

    chew tablets. JAMP-Memantine can be taken with or without food.

  • Continue to take JAMP-Memantine as long as directed

    by your doctor and you do not experience any unacceptable side effects. Your doctor should assess your treatment on a regular basis.

Overdose:

If you have accidentally taken too much JAMP-Memantine contact your regional Poison Control Centre, hospital emergency department or your doctor immediately, even if you do not feel sick. You may require medical attention. If you go to the doctor or the hospital, take the JAMP-Memantine container with you.

Missed Dose:

  • If you miss a dose, do not worry. Do not take the missed

    tablet(s) – just take the next dose when it is due.

SIDE EFFECTS AND WHAT TO DO ABOUT THEM

Like all medicines, JAMP-Memantine can cause side effects, although not everybody gets them. In general, these are mild to moderate. If any of the side effects become severe or if they are troublesome or persistent, talk to your doctor.

Common side effects (affects 1 to 10 users in 100) may include:

  • headache
  • sleepiness
  • constipation
  • tiredness
  • confusion
  • hallucinations (strange visions or sounds)
  • vomiting
  • loss of appetite
  • dizziness
  • sleep disturbance
  • anxiety
  • high blood pressure
  • change in frequency of urination

Uncommon side effects (affects 1 to 10 users in 1000) may include:

  • fungal infections

  • changes in vision

    • skin allergies

Your doctor will tell you whether your illness allows you to drive or operate machinery. Also, as this product may cause sleepiness or dizziness, do not drive or operate machinery under these conditions.

Alzheimer's disease has been associated with depression, thoughts of suicide and suicide. These events have been reported in patients treated with JAMP-Memantine.

If you have previously experienced epileptic seizures, there is a possibility that JAMP-Memantine may increase the chances of one occurring.

SERIOUS SIDE EFFECTS, HOW OFTEN THEY HAPPEN
AND WHAT TO DO ABOUT THEM
Symptom / effectTalk with your doctor orStop taking drug and seek immediate emergency treatment

Only if

sever

In all cases
UncommonFungal infection

e

√

Abnormal gait [Abnormal way of walking]√

Heart failure [persistent chest pain, rapid heart rate, severe

shortness of breath, swelling of legs or

ankles,

increased

tiredness, lack of appetite,

confusion]

√

Venous blood clotting [pain, swelling,

changes in skin color, increased warmth in one leg]

√
Very rare

Seizures [loss of consciousness with

uncontrollable shaking]

√
Hepatitis/hepatic failure [yellow skin and eyes, nausea, loss of appetite, dark- coloured urine]√
IMPORTANT: PLEASE READ
SERIOUS SIDE EFFECTS, HOW OFTEN THEY HAPPEN
AND WHAT TO DO ABOUT THEM

Symptom / effect

Inflammation of the pancreas [severe upper stomach pain, often with

nausea and

vomiting]

psychotic

reactions

Serious skin reactions [rash, red skin,

blistering of the lips, eyes or mouth, skin peeling]

Talk with your doctor

or

Stop taking drug and seek immediate emergency treatment

Only if

sever

In all cases
e

√

√

√
√
Very rare (continued)

For example: Stevens-

Johnson

Syndrome:

Severe

rash with

blisters and peeling skin, particularly around the

mouth,

nose, eyes

and genitals

Acute

Generalized Exanthematous Pustulosis: Red rash covered with small pus-filled bumps that can spread over the body, sometimes with a fever

Erythema

Multiforme: Rash that may blister, with spots that look like small targets

√

This is not a complete list of side effects. For any unexpected effects while taking JAMP-Memantine, contact your doctor or pharmacist.

If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

HOW TO STORE IT

  • As with all medicines, keep JAMP-Memantine out of the reach of children.
  • Store your tablets at room temperature (15°C-30°C) and in a dry place.
  • If your doctor tells you to stop taking your medicine you should return any leftover tablets to the pharmacist, unless the doctor tells you to keep them at home.

REMEMBER: This medicine is for YOU or for someone in your care. Only a doctor can prescribe it, so never offer it to any other person, even if their symptoms seem to be the same as yours or as for the person in your care.

MORE INFORMATION

This document plus the full Product Monograph, prepared for health professionals can be found at:

www.jamppharma.com or by contacting the manufacturer, JAMP Pharma Corporation at: 1-866-399-9091.

JAMP Pharma Corporation

1310 rue Nobel

Boucherville, Quebec

J4B 5H3, Canada

Date of Revision: December 6, 2021

Reporting Side Effects

You can report any suspected side effects associated with the use of health products to Health Canada by:

  • Visiting the Web page on Adverse Reaction Reporting

    (https://www.canada.ca/en/health-canada/services/ drugs- health-products/medeffect-canada/adverse-reaction- reporting.html) for information on how to report online,by mail or by fax; or

  • Calling toll-free at 1-866-234-2345.

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.

About this document

Source: Health Canada – Drug Product Database (DPD) and product monographs · DIN (Drug Identification Number): 02409887

Revision date stated in the text: December 6, 2021

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Jamp-Memantine

Rx or OTC
Prescription (Rx)?
DIN 02409887, 02409895
Schedule(s) PRESCRIPTION
Active ingredient(s) Memantine hydrochloride
Dosage form(s) Tablet
Route(s) of administration Oral
Drug class (WHO ATC)
  1. N Nervous system drugs
    1. N06 Psychoanaleptics
      1. N06D Anti-dementia drugs
        1. N06DX Other anti-dementia drugs
          1. N06DX01 Memantine
Company JAMP PHARMA CORPORATION
Current status Marketed
Current status date September 8, 2026
Strengths and forms
DIN Strength Dosage form(s) Current status
02409887 5 MG Tablet Marketed September 8, 2026
02409895 10 MG Tablet Marketed September 8, 2026

Source: Health Canada – Drug Product Database (DPD) and product monographs, data as of November 1, 2026. Data from the Health Canada Drug Product Database, as published there. Not a substitute for the advice of a doctor or pharmacist.