Jamp Ramipril Capsules: Uses, Side Effects and Dosage

ABOUT THIS MEDICATION

What the medication is used for:

High Blood Pressure (Hypertension)

JAMP Ramipril Capsules lowers high blood pressure. It can be used alone or together with a diuretic (“water pill”).

Following a Recent Heart Attack

JAMP Ramipril Capsules reduces the effort required by your heart to pump blood. This is to compensate for the reduced pumping power that may have resulted from your heart attack. JAMP Ramipril Capsules has been shown to improve survival and reduce hospitalizations for heart failure in patients that are now clinically stable and recovering from recent heart attacks.

For the Management of Patients at Increased Risk of Cardiovascular Events

Your doctor has prescribed JAMP Ramipril Capsules because:

• You have coronary heart disease (such as chest pains or angina, or have had a heart attack in the past)
• You had a stroke
• You have peripheral vascular disease (poor blood circulation)
• You have diabetes and at least one of the following physical conditions: high blood pressure, elevated total cholesterol levels, low high-density lipoprotein (HDL) levels, cigarette smoking or documented tiny amounts of albumin from your blood detected in your urine (microalbuminuria).

JAMP Ramipril Capsules may lower the risk of heart attack, stroke, or death from heart disease in some patients who have a heart problem or poor blood circulation.

Managing your lifestyle

Keeping your blood pressure controlled

It takes more than just medication to reduce blood pressure. Discuss the risk factors, and how they apply to your lifestyle, with your doctor. You may have to modify some of your daily habits to keep your blood pressure down.

Exercise regularly. It will help to keep your weight down; make you feel more energetic and is a good way to deal with stress. If you are not exercising regularly, be sure to discuss a fitness plan with your doctor.

Remember, hypertension is a long-term disease without symptoms. Just because you feel fine does not mean you can stop taking your medication. If you stop, serious complications of the disease may occur. Therefore, you should continue to take JAMP Ramipril Capsules regularly, as prescribed by your doctor.

The "lifestyle" part of your treatment is as important as your medication. By working as a team with your doctor, you can help reduce the risk of complications to maintain the style of life you are accustomed to.

• Alcohol: Avoid alcoholic beverages until you have discussed their use with your doctor. Alcohol consumption may alter your blood pressure and / or increase the possibility of dizziness or fainting.

• Diet: Generally, avoid fatty foods and food that is high in salt or cholesterol.
• Smoking: Avoid it completely.

What it does:

JAMP Ramipril Capsules is an angiotensin converting enzyme (ACE) inhibitor. You can recognize ACE inhibitors because their medicinal ingredient ends in ‘-PRIL’.

JAMP Ramipril Capsules opens blood vessels to reduce blood pressure, just like the way opening a hose reduces water pressure.

This medicine does not cure your disease. It helps to control it. Therefore, it is important to continue taking JAMP Ramipril Capsules regularly even if you feel fine.

When it should not be used:

Do not take JAMP Ramipril Capsules if you:

• Are allergic to ramipril or to any non-medicinal ingredient in the formulation.
• Have experienced an allergic reaction (angioedema) with swelling of the hands, feet, or ankles, face, lips, tongue, throat, or sudden difficulty breathing or swallowing, to any ACE inhibitor or without a known cause. Be sure to tell your doctor, nurse, or pharmacist that this has happened to you.
• Have been diagnosed with hereditary angioedema: an increased risk of getting an allergic reaction that is passed down through families. This can be triggered by different factors, such as surgery, flu, or dental procedures.
• Are pregnant or intend to become pregnant. Taking JAMP Ramipril Capsules during pregnancy can cause injury and even death to your baby.
• Are breastfeeding. JAMP Ramipril Capsules passes into breast milk.
• Are taking ENTRESTO^® (sacubitril / valsartan), due to the increased risk of serious allergic reaction which causes swelling of the face or throat (angioedema) when taken

IMPORTANT: PLEASE READ

with JAMP Ramipril Capsules. You must wait at least 36 hours after your last dose of sacubitril / valsartan before taking JAMP Ramipril Capsules.

• Have narrowing of the arteries to one or both kidneys (renal artery stenosis).
• Have hypotension (low blood pressure).
• Are on dialysis or LDL apheresis (a treatment to remove LDL cholesterol from the blood).

• Are already taking a blood pressure-lowering medicine containing aliskiren (such as RASILEZ^®) and you have one of the following conditions:

  • diabetes
  • kidney disease
  • high potassium levels
  • heart failure combined with low blood pressure

• Are taking an angiotensin receptor blocker (ARB), another medicine to treat your high blood pressure, or another ACE inhibitor and have one of the following conditions:

  • diabetes with end-organ damage
  • kidney disease
  • high potassium levels
  • heart failure combined with low blood pressure

You can recognize an ARB because its medicinal ingredient ends in “-SARTAN”.

What the medicinal ingredient is:

Ramipril

What the non-medicinal ingredients are:

Fumed silica, gelatin, pre-gelatinized starch and coloring agents (containing FD&C Blue No. 1 (5 mg), FD&C Red No. 3 (5 mg), FD&C Red No. 40 (5 mg), iron oxide yellow (1.25 mg), and titanium dioxide). The imprinting black ink used on the capsules contains iron oxide black, potassium hydroxide, propylene glycol, shellac and strong ammonia solution.

What dosage forms it comes in:

Capsules: 1.25 mg and 5 mg.

WARNINGS AND PRECAUTIONS

BEFORE you use JAMP Ramipril Capsules talk to your doctor, nurse, or pharmacist if you:

• Are allergic to any drug used to lower blood pressure.
• Have recently received or are planning to get allergy shots for bee or wasp stings.
• Have narrowing of an artery or a heart valve.
• Have had a heart attack or stroke.
• Have diabetes.
• Have liver disease. Your doctor should take blood tests to measure your liver function before you start taking JAMP Ramipril Capsules and occasionally throughout your treatment.
• Have kidney disease. Your doctor should take regular blood tests to measure your kidney function and the levels of potassium in your blood.
• Have Raynaud's phenomenon which is a condition resulting from poor circulation in the extremities (i.e., fingers and toes). It may begin or get worse.
• Have diabetes, liver or kidney disease.
• Are on dialysis or LDL apheresis (a treatment to remove LDL cholesterol from the blood).
• Are dehydrated or suffer from excessive vomiting, diarrhea, or sweating.
• Are taking a salt substitute that contains potassium, potassium supplements, a potassium-sparing diuretic (a specific kind of “water pill”), or other medicinal products that may increase potassium. Use of JAMP Ramipril Capsules with these medicines is not recommended.
• Are on a low-salt diet.
• Are receiving gold (sodium aurothiomalate) injections.
• Are less than 18 years old.
• Are taking a medicine that contains aliskiren, such as RASILEZ^®, used to lower high blood pressure. The combination with JAMP Ramipril Capsules is not recommended.
• Are taking an angiotensin receptor blocker (ARB). You can recognize an ARB because its medicinal ingredient ends in “-SARTAN”. The combination with JAMP Ramipril Capsules is not recommended.

• Are taking drugs such as:

  • Temsirolimus and everolimus (used to treat cancer),
  • Sirolimus (used to prevent organ rejection after a transplant),
  • Sitagliptin or other gliptins (used to treat Type II diabetes),
  • A neutral endopeptidase inhibitor

Taking ACE inhibitors, such as JAMP Ramipril Capsules, with these types of drugs may increase your chances of having an allergic reaction (angioedema). You may become sensitive to the sun while taking JAMP Ramipril Capsules. Exposure to sunlight should be minimized until you know how you respond.

If you are going to have surgery and will be given an anesthetic, be sure to tell your doctor or dentist that you are taking JAMP Ramipril Capsules.

IMPORTANT: PLEASE READ

Serious Warnings and Precautions – Pregnancy

JAMP Ramipril Capsules should not be used during pregnancy. If you discover that you are pregnant while taking JAMP Ramipril Capsules, stop the medication and please contact your doctor, nurse, or pharmacist as soon as possible.

Driving and using machines

Before you perform tasks which may require special attention, wait until you know how you respond to JAMP Ramipril Capsules. Dizziness, lightheadedness, or fainting can especially occur after the first dose and when the dose is increased.

INTERACTIONS WITH THIS MEDICATION

As with most medicines, interactions with other drugs are possible. Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines.

The following may interact with JAMP Ramipril Capsules:

• Agents increasing serum potassium, such as a salt substitute that contains potassium, potassium supplements, a potassium-sparing diuretic (a specific kind of “water pill”), or other medicinal products that may increase potassium. Use of JAMP Ramipril Capsules with these medicines is not recommended.
• Alcohol
• Allopurinol used to treat gout.
• Antidiabetic drugs, including insulin and oral medicines, such as gliptins (e.g., sitagliptin).
• Lithium used to treat bipolar disease.
• Gold for the treatment of rheumatoid arthritis.
• Nonsteroidal anti-inflammatory drugs (NSAIDs), used to reduce pain and swelling. Examples include ibuprofen, naproxen, and celecoxib.
• Blood pressure-lowering drugs, including diuretics (“water pills”), aliskiren-containing products (e.g., RASILEZ^®), or angiotensin receptor blockers (ARBs).
• Nitrates used to treat angina (chest pain)
• Acetylsalicylic acid (aspirin)
• Heparin used to prevent and treat blood clots
• Immunosuppressants used to lower the body’s ability to reject a transplanted organ
• Corticosteroids used to treat joint pain and swelling or for other conditions.
• Procainamide used to treat irregular heartbeat
• Cytostatic medicines used to treat certain types of cancer
• mTOR inhibitors used to lower the body’s ability to reject a transplant (e.g., sirolimus) or to treat certain types of cancer (e.g., temsirolimus, everolimus)
• Neutral endopeptidase (NEP) inhibitors.

PROPER USE OF THIS MEDICATION

Take JAMP Ramipril Capsules exactly as prescribed. It is recommended to take your dose at about the same time every day.

Usual adult dose:

High Blood Pressure: The recommended initial dosage of JAMP Ramipril Capsules is 2.5 mg once daily. Your doctor will determine the appropriate dosage.

Following a Recent Heart Attack: The recommended initial dosage of JAMP Ramipril Capsules is 2.5 mg given twice a day in the morning and in the evening for patients with clinical signs of heart failure (a condition in which the heart has difficulty pumping enough blood to the body's other organs). Treatment should be started under close medical supervision.

For Patients Taking Diuretics (“water pills”) or With Impaired Kidney Function: The recommended initial dosage of JAMP Ramipril Capsules is 1.25 mg daily.

Management of Patients at Increased Risk of Cardiovascular Events: The recommended initial dosage of JAMP Ramipril Capsules is 2.5 mg once daily. Your doctor will determine the appropriate dosage.

Overdose:

Missed Dose:

If you have forgotten to take your dose during the day, carry on with the next one at the usual time. Do not double dose.

SIDE EFFECTS AND WHAT TO DO ABOUT THEM

Side effects may include:

• dizziness, difficulty in maintaining your balance while standing
• drowsiness, fatigue, weakness
• cough, nasal or sinus congestion, swollen lymph nodes, bronchitis, aggravated asthma
• rash, itching, flushing, inflammation of the eye (pink eye), skin inflammation or red skin, burning sensation, inflammation of the mouth or tongue
• headache
• abdominal pain
• sad mood, difficulty with sleep, restlessness, attention disturbances
• loss of hair
• taste modifications or loss of taste, vision or hearing modifications
• impotence / reduced libido, breast enlargement in males

If any of these affects you severely, tell your doctor, nurse or pharmacist.

JAMP Ramipril Capsules can cause abnormal blood test results. Your doctor will decide when to perform blood tests and will interpret the results.

IMPORTANT: PLEASE READ

If you think you, or a person you are caring for, have taken too much JAMP Ramipril Capsules, contact a healthcare professional, hospital emergency department, regional poison control centre or Health Canada’s toll-free number,

1-844 POISON-X (1-844-764-7669) immediately, even if there are no signs or symptoms.

This is not a complete list of side effects. For any unexpected effects while taking JAMP Ramipril Capsules, contact your doctor, nurse or pharmacist.

HOW TO STORE IT

Store at room temperature, 15- 30ºC.

Do not use after the expiry date stated on the carton, blister or bottle.

Keep out of reach and sight of children.

IMPORTANT: PLEASE READ

Reporting Side Effects

MORE INFORMATION

• Talk to your healthcare professional
• Find the full Product Monograph that is prepared for healthcare professionals and includes the Consumer Information by visiting the Health Canada Drug Product Database website (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); or by calling at 1-866-399-9091.

JAMP Pharma Corporation

1310 rue Nobel

Boucherville, Québec

J4B 5H3, Canada

Last Revised: 2026-07-24

IMPORTANT: PLEASE READ