Jamp Tolterodine: Uses, Side Effects and Dosage

ABOUT THIS MEDICATION

What the medication is used for:

The name of this medication is JAMP TOLTERODINE. It is used for the treatment of the symptoms of overactive bladder which include frequency, urgency, and urge incontinence.

REMEMBER: This medication is for YOU. Never give it to others. It may harm them even if their symptoms are the same as yours.

What it does:

Tolterodine prevents bladder contractions or spasms. This results in more bladder capacity and less frequency, urgency and involuntary loss of urine.

When it should not be used:

You should not take JAMP TOLTERODINE if you have:

• urinary retention,
• gastric retention
• uncontrolled narrow angle glaucoma,
• known hypersensitivity to the tolterodine L-tartrate or any of the other ingredients.

What the medicinal ingredient is:

Each tablet contains 1 mg or 2 mg of the active ingredient tolterodine L-tartrate.

What the nonmedicinal ingredients are:

The tablets also contain the following inactive ingredients: colloidal anhydrous silica, calcium hydrogen phosphate dihydrate, hypromellose, magnesium stearate, cellulose microcrystalline, sodium starch glycolate, stearic acid, and titanium dioxide.

What dosage forms it comes in:

JAMP TOLTERODINE 1 mg tablets are white to off white round, biconvex, film coated debossed with ‘CL 60’ on one side and plain on other side.

JAMP TOLTERODINE 2 mg tablets are white to off white round, biconvex, film coated debossed with ‘CL 61’ on one side and plain on other side.

WARNINGS AND PRECAUTIONS

JAMP TOLTERODINE may have an effect on the electrical activity of the heart. This effect can be measured as a change in the electrocardiogram (ECG). It is important to follow the instructions of your doctor with regard to dosing or any special tests. In very rare cases, drugs with an effect on the ECG can lead to disturbances in heart rhythm (arrhythmias/dysrhythmias). These heart rhythm disturbances are more likely in patients with risk factors, such as heart disease, or in the presence of certain interacting drugs. If you experience any symptoms of a possible heart rhythm disturbance, such as dizziness, palpitations (sensation of rapid pounding, or irregular heart beat), fainting, or seizures, you should stop taking JAMP TOLTERODINE and seek immediate medical attention.

BEFORE you use JAMP TOLTERODINE talk to your doctor or pharmacist if:

• you are pregnant, or trying to become pregnant

• you are breastfeeding your child
• you have myasthenia gravis (a chronic autoimmune neuromuscular disease which cause muscle weakness)
• you have stomach problems affecting passage and digestion of food
• you have liver problems
• you have kidney problems
• you are taking medication bought without a prescription. They may affect your condition, or how JAMP TOLTERODINE works for you.
• you are a female or are over 65 years in age; you have a disorder known as Long QT Syndrome; a heart disease; a history of stroke or brain hemorrhage; a personal history of fainting spells; a family history of sudden cardiac death at <50 years; electrolyte disturbances (e.g., low blood potassium levels); an eating disorder or are following an extreme diet; diabetes, especially with associated nerve disorders

INTERACTIONS WITH THIS MEDICATION

The following list includes some, but not all, of the drugs that may increase the risk of side effects while receiving JAMP TOLTERODINE. You should check with your doctor or pharmacist before taking any other medication with JAMP TOLTERODINE.

Drugs that may interact with JAMP TOLTERODINE include:

• other drugs that possess antimuscarinic/anticholinergic properties (drugs that cause blurred vision, constipation, dry mouth, etc.)
• antifungals (drugs to treat fungal infections , such as, fluconazole, ketoconazole, or itraconazole) antibiotics (ie. erythromycin, clarithromycin)
• cyclosporine (a drug to prevent rejection of organ transplants)
• vinblastine (a drug to treat some types of cancer)
• antiarrhythmics (drugs that stabilize the heart rhythm function, such as procainamide, quinidine, amiodarone, sotalol etc.)
• antidepressants (mood disorder drugs)
• antipsychotics (drugs to stabilize thinking and behavior)
• anti-asthmatic (salmeterol)

PROPER USE OF THIS MEDICATION

Take JAMP TOLTERODINE as instructed by your doctor. Do not increase, decrease or stop taking JAMP TOLTERODINE without first talking to your doctor.

Usual dose:

The usual starting dose is 2 mg twice daily, but may be decreased to 1 mg twice daily.

Overdose:

Do not take more tablets than your doctor has told you to. If you take too many tablets by accident, call your doctor or pharmacist or a poison control centre immediately.

Missed Dose:

If you should forget to take your tablet at the usual time, take it as soon as you remember unless it is time to take the next one. Continue with the remaining doses as before. Do not take more than one dose at a time.

SIDE EFFECTS AND WHAT TO DO ABOUT THEM

As with most drugs, JAMP TOLTERODINE can cause some side effects.

Tell your doctor or pharmacist right away if you suffer from any of the following side effects while taking this medication:

• dry mouth
• decreased tear production (dry irritable eye)
• heartburn
• blurred vision
• dizziness
• palpitations (sensation of rapid, pounding, or irregular heart beat)
• fainting
• difficulty in urination (passing water)

The most common side effects are dry mouth and headache. Less commonly reported side effects are dizziness, fatigue, abdominal pain, constipation and heartburn.

If you experience any symptoms of a possible heart rhythm disturbance, such as dizziness, palpitations (sensation of rapid, pounding, or irregular heart beat), fainting, or seizures, you should stop taking JAMP TOLTERODINE and seek immediate medical attention.

Check with your doctor or pharmacist right away if you have any bothersome or unusual effects while taking JAMP TOLTERODINE.

Use caution while driving or using machinery until you know how JAMP TOLTERODINE affects you.

This is not a complete list of side effects. For any unexpected effects while taking JAMP TOLTERODINE, stop taking the drug and contact your doctor or pharmacist.

HOW TO STORE IT

Store at room temperature 15ºC to 30ºC.

You should not use your medication after the expiration date printed on the carton and label.

Keep all medications out of the reach and the sight of children. This medication could harm them.

REPORTING SIDE EFFECTS

MORE INFORMATION

This document plus the full Product Monograph, prepared for Health Professionals can be found by contacting the sponsor, JAMP Pharma Corporation, at 1-866-399-9091

Last Approved: March 05, 2020