Patient Medication Information: uses, side effects, how to take - Lumigan Pf
What is LUMIGAN PF used for?
LUMIGAN PF eye drops are used to reduce high pressure in the eye in adult patients with open angle glaucoma or ocular hypertension. If the high pressure is not reduced, it could eventually damage your sight. Since LUMIGAN PF does not contain a preservative, it may be used in patients who could benefit from preservative‐free drops.
How does LUMIGAN PF work?
LUMIGAN PF is an antiglaucoma preparation. It belongs to a group of medicines called prostamides. Your eye contains a clear, watery liquid that feeds the inside of the eye. Liquid is constantly being drained out of the eye and new liquid is made to replace this. If the liquid cannot drain out quickly enough, the pressure inside the eye builds up. LUMIGAN PF works by increasing the flow of liquid that is drained. This reduces the pressure inside the eye.
What are the ingredients in LUMIGAN PF?
Medicinal ingredients: Bimatoprost
Non‐medicinal ingredients: Sodium chloride, sodium phosphate dibasic heptahydrate, citric acid monohydrate, and purified water. Sodium hydroxide and/or hydrochloric acid may be added to adjust pH.
LUMIGAN PF comes in the following dosage forms:
Ophthalmic solution, 0.03% w/v
Do not use LUMIGAN PF if:
- you are allergic to bimatoprost, to any of the other ingredients, or to any of the parts of the container (see section What are the ingredients).
To help avoid side effects and ensure proper use, talk to your healthcare professional before you use LUMIGAN PF. Talk about any health conditions or problems you may have, including if you:
- are taking, or have recently taken, any other medicines. Using LUMIGAN PF with other medicines or other antiglaucoma products may redue their effectiveness.
are pregnant or planning to become pregnant. You should ask your healthcare professional for advice before taking any medicine.
are breastfeeding or planning to breastfeed. Ask your healthcare professional how to feed your baby while using
LUMIGAN PF.
- have an active eye infection, inflammation (e.g. uveitis) or any other eye or eyelid condition.
- develop another eye condition (an injury or an infection).
- need to have eye surgery.
- have liver or kidney problems.
Other warnings you should know about:
Changes in Eye and Eyelid Color
LUMIGAN PF has been associated with iris pigmentation (change in the colored part of the eye). This is likely to be permanent. The change may be more noticeable if you are only treating one eye. Using too much LUMIGAN PF (overdose) may contribute to iris pigmentation. LUMIGAN PF use may also cause darkening of the eyelid skin which may be reversible in most patients.
Hair Growth
It is possible for hair growth to occur in areas of your skin that LUMIGAN PF frequently touches. Any excess solution that drips from the eye should be blotted with a tissue or other absorbent material to reduce the chance of this from happening. It is also possible for a difference in eyelash length, thickness, fullness, pigmentation, number of eyelash hairs, and/or direction of eyelash growth to occur between eyes. These differences, should they occur, will usually go away if you stop using LUMIGAN PF.
Changes in Vision
Using LUMIGAN PF may temporarily blur your vision. Do not drive or use machines until your vision has cleared.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with LUMIGAN PF:
No drug interaction studies have been done with LUMIGAN PF.
How to use LUMIGAN PF:
- Always use LUMIGAN PF exactly as your healthcare professional has instructed you.
- Make sure the vial is not damaged before using it. If the vial is not intact, discard it.
- LUMIGAN PF must be used immediately after opening the vial.
- If you wear contact lenses, remove them before using LUMIGAN PF. Wait 15 minutes after using the drops before you put your lenses back in.
- If you use LUMIGAN PF with another eye drop, wait at least five minutes after using LUMIGAN PF before using the other drops.
- To help prevent infection, do not let the open end of the vial touch your eye or anything else.
Follow these steps to use LUMIGAN PF properly:
- 1. Wash your hands. Tear 1 vial from the strip. (See Illustration 1)
- 2. Hold the vial upright (with the cap pointing upwards) and twist off the cap. (See Illustration 2)
- 3. Gently pull down the lower eyelid to form a pocket. Turn the vial upside down and squeeze it to release 1 drop into the eyelid pocket. If a drop missed your eye, try again. (See Illustration 3)
- 4. Repeat stpes 1 – 3 in the other eye if both eyes need treatment.
- 5. Throw away the vial after you have used it, even if there is some solution left. (See Illustration 4)
Usual adult dose:
The recommended dosage is 1 drop of LUMIGAN PF in the each eye that needs treatment, once daily in the evening.
Overdose:
If you think you have used too much LUMIGAN PF, contact your healthcare practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
If you accidentally use too many drops, just go back to your regular once a day dosing the next day.
Missed Dose:
If you forget to take LUMIGAN PF use a single drop as soon as you remember, and then go back to your regular routine. Do not take two doses to make up for the one that you missed.
What are possible side effects from using LUMIGAN PF?
These are not all the possible side effects you may feel when taking LUMIGAN PF. If you experience any side effects not listed here, contact your healthcare professional.
Side effects may include:
- Longer eyelashes, change in eyelash color
- Eye irritation, redness, itching, dryness
- Burning or stinging sensation in the eye
- Feeling that something is in your eye
- Eye pain
- Eye discharge
- Abnormal vision
- Red and itchy eyelids
- Darkening of the eyelid
- Inflammation of the eyelid
- Small breaks in the surface of the eye
- Sensitivity to light
- Tearing
- Tired eyes
- Dizziness
- Headache
Some patients (fewer than 2 in every 100) experience a change in iris color (iris pigmentation). The change is a darkening, with the eyes becoming more brown. This usually happens during the first year of treatment. Eye color darkening is expected to increase as long as LUMIGAN PF is used. It is not known what this change means over the long term. Talk to your healthcare professional if you notice a change in your iris color.
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health‐canada/services/drugs‐health‐products/medeffect‐canada.html ) for information on how to report online, by mail or by fax; or
- Calling toll‐free at 1‐866‐234‐2345.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
Storage:
LUMIGAN PF should be stored in the original container at 15ºC to 25ºC.
Do not use the drops after the expiry date stated on the single‐dose container and the tray.
Once the tray is opened, the single‐dose containers (vials) should be used within 30 days.
Keep out of the reach and the sight of children.
Do not freeze.
If you want more information about LUMIGAN PF:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website ( https://www.canada.ca/en/health‐canada.html ); the manufacturer’s website allergan.ca, or by calling 1‐800‐668‐6424.
Last revised November 26, 2018
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