Motrin Platinum Muscle & Body: Uses, Side Effects and Dosage

What is MOTRIN® Platinum Muscle & Body used for?

• For effective relief of pain associated with muscle spasm such as back pain, tense neck muscles, strains and sprains

How does MOTRIN® Platinum Muscle & Body work?

Ibuprofen reduces pain, fever and inflammation. Methocarbamol is a muscle relaxant. Ibuprofen is a member of a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs work within the body by decreasing the production of substances, called prostaglandins which are involved in the development of pain and inflammation. Methocarbamol is thought to act on the central nervous system.

What are the ingredients in MOTRIN® Platinum Muscle & Body?

Medicinal ingredients: Ibuprofen and methocarbamol.

Non-medicinal ingredients: Carnauba wax, colloidal silicon dioxide, FD&C yellow no. 6, hypromellose, microcrystalline cellulose, povidone, sodium lauryl sulphate, sodium starch glycolate, stearic acid, triacetin.

Serious Warnings and Precautions

• Caution in those with heart failure, high blood pressure or other conditions predisposing to fluid retention.
• Caution in those prone to gastrointestinal tract irritation, diverticulosis (a disease affecting colon), or other inflammatory disease of the gastrointestinal tract such as ulcerative colitis or Crohn’s disease.
• Caution in those at risk of kidney or liver problems, those taking diuretics and the elderly.
• Stop use immediately if you have difficulty or pain when urinating.

• Talk to your doctor if you are trying to conceive, in your first or second trimester of pregnancy or if breastfeeding.

MOTRIN® Platinum Muscle & Body comes in the following dosage forms:

Tablet, ibuprofen 200 mg and methocarbamol 500 mg.

Do not use MOTRIN® Platinum Muscle & Body if:

• You are:

  • taking acetylsalicylic acid (ASA) or any other nonsteroidal anti-inflammatory medication including any other ibuprofen product.
  • allergic/hypersensitive to ibuprofen or other non-steroidal anti-inflammatory drugs (NSAIDs), ASA or other salicylates, methocarbamol or to any of the MOTRIN® Platinum Muscle & Body caplets ingredients (Refer to the inactive ingredients on outer carton or see Non-medicinal ingredients above) or any component of the container. Allergic reactions may appear as hives, difficulty breathing, shock, skin reddening, rash or blisters, swelling of the face or throat, or sudden collapse.
  • dehydrated (significant fluid loss) due to vomiting, diarrhea or lack of fluid intake.
  • in your third trimester of pregnancy.

• You have:

  • peptic ulcer disease or gastrointestinal bleeding or any other active inflammatory disease of the gastrointestinal tract (e.g. colitis, Crohn’s disease).
  • nasal polyps (growth inside your nose), or allergic manifestations such as asthma, anaphylaxis (sudden severe life-threatening anaphylactic reactions), urticaria/hives, rhinitis (stuffed or runny nose that may be due to allergies), skin rash or other allergic symptoms.
  • serious liver or kidney disease.
  • Systemic Lupus Erythematosus.
  • high potassium in the blood.
• You recently had or are about to have heart surgery.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take MOTRIN® Platinum Muscle & Body. Talk about any health conditions or problems you may have, including if you:

• have diabetes, high blood pressure, heart or thyroid disease, asthma, mild to moderate kidney or liver disease, glaucoma, blood clotting disorder (such as hemophilia), or history of stomach bleeding or any other serious disease.
• are pregnant or breastfeeding
• are under a doctor’s care for any serious condition
• are older than 65 years of age
• are taking any other drug, including over the counter drugs.

Other warnings you should know about:

• May cause drowsiness or dizziness. Exercise caution in operating machinery or motor vehicles.

• Avoid alcohol.
• Use with caution in the elderly.
• Long-term continuous use may increase the risk of heart attack or stroke.
• The use of NSAIDs, like MOTRIN® Platinum Muscle & Body, in the second trimester of pregnancy should be restricted to the lowest dose necessary for shortest possible duration.
• At 20 weeks or later in pregnancy, your use of NSAIDs may need to be monitored by a health care practitioner due to the rare risk of kidney problems in the unborn baby which may result in decreased amniotic fluid volume and other complications.

Stop use and ask a doctor if

• you show signs of stomach bleeding
• pain worsens or lasts more than 5 days
• you have chest pain
• any new or unusual symptoms appear
• you get a rash or itchy skin

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

The following may interact with MOTRIN® Platinum Muscle & Body:

• acetaminophen
• anticoagulants (blood thinners)
• ASA or other NSAIDs
• digoxin
• diuretics (water pills)
• lithium
• medications for high blood pressure
• methotrexate
• oral antidiabetic agents and insulin
• protein-bound drugs including probenecid, thyroxine, antibiotics, cyclosporine, phenytoin, corticosteroids or benzodiazepines

Do not use this product if you are taking ASA. Ibuprofen may interfere with the preventative benefits of ASA.

How to take MOTRIN® Platinum Muscle & Body:

Take with food or milk if upset stomach occurs.

Usual dose:

Adults and children over 12: Take 1 or 2 caplets every four to six hours as needed. Do not exceed 6 caplets in 24 hours, unless directed by a physician. Use the lowest effective dose for the shortest duration. Do not use longer than 5 days without consulting your physician.

Overdose:

If you think you, or a person you are caring for, have taken too much MOTRIN® Platinum Muscle & Body, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms.

Missed Dose:

Continue to take 1-2 tablets every 4-6 hours as needed after a missed dose. Do not take twice the recommended dose following a missed dose.

What are possible side effects from using MOTRIN® Platinum Muscle & Body?

These are not all the possible side effects you may have when taking MOTRIN® Platinum Muscle & Body. If you experience any side effects not listed here, tell your healthcare professional.

MOTRIN® Platinum Muscle & Body may occasionally produce unwanted side effects, such as heartburn, constipation, nausea, bloating, sudden stomach pain or long-term stomach pain with the loss of appetite and/or new onset of itching, diarrhea, decreased appetite, headache, drowsiness, depression, tiredness, nervousness or sleeplessness, coloured urine, menstrual delays.

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Reporting Side Effects

You can report any suspected side effects associated with the use of health products to Health Canada by:

• Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada.html) for information on how to report online, by mail or by fax; or
• Calling toll-free at 1-866-234-2345.

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.

Storage:

Store at 15 to 30^oC. Protect from moisture.

Keep out of reach and sight of children. This package contains enough medicine to seriously harm a child.

If you want more information about MOTRIN® Platinum Muscle & Body:

• Talk to your healthcare professional
• Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); the manufacturer’s website www.motrin.ca, or by calling 1-888-6MOTRIN / 1-888-666-8746.

Last Revised: February 26, 2026