Patient Medication Information: uses, side effects, how to take - Myinfla
What is MYINFLA used for?
MYINFLA is used to reduce cardiovascular risks in patients with plaque build-up in the arteries, which narrows the arteries and restricts the blood supply to the heart.
How does MYINFLA work?
It is not exactly known how MYINFLA works to reduce cardiovascular risks, but it may help to reduce inflammation in the arteries. MYINFLA is not a pain medicine. It should not be taken to treat pain or other conditions.
What are the ingredients in MYINFLA?
Medicinal ingredients: Colchicine
Non-medicinal ingredients: Ammonio methacrylate copolymer, FD&C Blue #1, glyceryl monostearate, invert sugar syrup, iron oxide yellow, magnesium stearate, maltodextrin, polyethylene glycol, polyvinyl alcohol-part hydrolyzed, polysorbate 80, povidone, sodium starch glycolate, sucrose, talc, titanium dioxide, triethyl citrate, water.
MYINFLA comes in the following dosage forms:
Extended-release tablets, 0.5 mg
Do not use MYINFLA if:
- you are allergic to colchicine or any of the other ingredients of this medicine.
- you have kidney or liver problems.
- you have a blood disorder.
you are taking the following medications:
- Atazanavir
- Clarithromycin
- Cyclosporine
- Darunavir / ritonavir
- Indinavir
- Itraconazole
- Ketoconazole
- Lopinavir / ritonavir
- Refazodone
- Nelfinavir
- Ranolazine
- Ritonavir
- Saquinavir
- Telithromycin
- Tipranavir
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take MYINFLA. Talk about any health conditions or problems you may have, including if you:
- have liver or kidney problems
- have gastrointestinal problems
are pregnant or plan to become pregnant. It is not known if MYINFLA will harm your unborn baby. Talk to your healthcare provider if you are pregnant or plan to become pregnant or are a male with a female partner who can become pregnant. Receiving treatment with colchicine may be related to infertility in some men that is reversible when treatment is stopped.
- are breastfeeding or plan to breastfeed. Colchicine passes into breast milk.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
MYINFLA can cause serious side effects or death if levels of MYINFLA are too high in your body. Taking certain medicines with MYINFLA can cause your level of MYINFLA to be too high, especially if you have kidney or liver problems.
The following may interact with MYINFLA:
- Certain antibiotics (used to treat infections) such as erythromycin
- Anti-viral drugs (used to treat HIV infection) such as fosamprenavir
- Anti-fungal medicines such as fluconazole
- Certain heart medicines such as verapamil and diltiazem
- Digoxin (used to treat certain heart conditions)
- Medicines used to lower cholesterol such as gemfibrozil, ‘fibrates’, atorvastatin, rosuvastatin and simvastatin
- Aprepitant (used to prevent nausea and vomiting caused by cancer treatment)
Avoid eating grapefruit or drinking grapefruit juice while taking MYINFLA. It can cause your level of colchicine to be too high and increase your chances of getting serious side effects.
How to take MYINFLA:
Always take this medicine exactly as your healthcare professional has told you. MYINFLA can be toxic, so it is important that you do not exceed the dose prescribed by your healthcare professional.
Check with your healthcare professional if you are not sure. Your healthcare professional will tell you how many MYINFLA tablets to take, when to take them, and for how long you should take them.
Usual dose:
Take 1 tablet once daily, with or without food.
Overdose:
At too high a dose MYINFLA can be seriously toxic, even fatal. Early symptoms of overdose (which appear within 24 hours, but can take longer) include nausea, vomiting, stomach pain, diarrhea or low blood pressure.
| If you think you, or a person you are caring for, have taken too much MYINFLA, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms. |
Missed Dose:
If you miss a dose, then take it as soon as you remember. If it is almost time for your next dose, just skip the missed dose and take the next dose at your regular time. Do not take 2 doses at the same time.
What are possible side effects from using MYINFLA?
These are not all the possible side effects you may have when taking MYINFLA. If you experience any side effects not listed here, tell your healthcare professional.
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
|---|---|---|---|
| Only if severe | In all cases | ||
| COMMON | |||
| Diarrhea | X | ||
| Gastrointestinal issues: cramping, stomach pain, nausea, vomiting | X | ||
| UNCOMMON | |||
| Anemia: fatigue, weakness, dizziness or feeling lightheaded, headache, cold hands or feet, shortness of breath | X | ||
| Severe skin rash: redness, blistering and/or peeling of the skin and/or inside of the lips, eyes, mouth, nasal passages or genitals, accompanied by fever, chills, headache, cough, feeling thirsty, urinating less, body aches or swollen glands | X | ||
| Cholestasis (decrease in bile flow from the liver): jaundice (yellowing of the skin or whites of eyes), dark urine, light coloured stools, loss of appetite | X | ||
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help |
|---|
| Only if severe | In all cases | ||
|---|---|---|---|
| RARE | |||
| Muscle weakness or pain | X | ||
| Numbness or tingling in your fingers or toes | X | ||
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Store at room temperature between 15°C and 30°C.
Keep out of reach and sight of children. Dispose of any unused medicines at your local pharmacy.
If you want more information about MYINFLA:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html; or by contacting the manufacturer through their website http://www.pendopharm.com, or by calling 1-888-550-6060.
This information is current up to the time of the last revision date shown below, but more current information may be available from the manufacturer.
Last Revised AUG 20, 2021
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