Patient Medication Information: uses, side effects, how to take - Negative Skin Test Control - Glycerin
Serious Warnings and Precautions
- The product should only be provided by physicians who are experienced in the use of allergenic extracts, or for use under the guidance of an allergist.
- Allergenic extracts may potentially cause a severe life-threatening systemic reaction (anaphylaxis), which can result in death. Therefore, emergency measures and personnel trained in their use must be available immediately in the event of such a reaction. You should also be instructed to recognize serious symptoms and contact the physician’s office if symptoms occur.
- If you are on beta blockers, you may be more reactive to allergens given for testing or treatment and may be unresponsive to the usual doses of epinephrine used to treat allergic reactions.
- The diagnosis process with this product should not cause bleeding.
What are ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS or NEGATIVE SKIN TEST CONTROL – GLYCERIN used for?
“ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS and NEGATIVE SKIN TEST CONTROL – GLYCERIN have been approved for the following indication(s) by Health Canada. This means they have passed Health Canada’s review and can be purchased and administered in Canada. For more information, talk to your healthcare professional.”
- These products are used for the diagnosis of patients with specific allergic conditions.
How do ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS and NEGATIVE SKIN TEST CONTROL – GLYCERIN work?
You will have allergenic extracts placed on your skin. A prick will be made through the extract into your skin. If you are allergic to a specific extract, a bump in the skin will form. Your physician will measure the bump. Based on the size of the bump, the physician will determine if treatment (immunotherapy) is an option to relieve or lessen your responses to that allergen.
What are the ingredients in ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS and NEGATIVE SKIN TEST CONTROL – GLYCERIN?
ALLERGENIC EXTRACT – POLLENS:
Medicinal ingredients: Various Pollen Extracts
Non-medicinal ingredients: Glycerin, Sodium chloride and Sodium bicarbonate
ALLERGENIC EXTRACT – NON-POLLENS:
Medicinal ingredients: Various Epidermal, Insect and Mold Extracts
Non-medicinal ingredients: Glycerin, Sodium chloride and Sodium bicarbonate
NEGATIVE SKIN TEST CONTROL – GLYCERIN:
Non-medicinal ingredients: Glycerin, Sodium chloride and Sodium bicarbonate
ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS and NEGATIVE SKIN TEST CONTROL – GLYCERIN come in the following dosage forms:
ALLERGENIC EXTRACT – POLLENS:
Dosage Form: Solution
Strength (Product Dependent): 1:20 w/v, 1:50 w/v, 100 Amb a 1 UA/mL and 200 Amb a 1 UA/mL)
ALLERGENIC EXTRACT – NON-POLLENS:
Dosage Form – Solution
Strength (Product Dependent): 1:10 w/v, 1:50 w/v, 1:100 w/v, 1:650 w/v and 1:1,000 w/v)
NEGATIVE SKIN TEST CONTROL – GLYCERIN:
Dosage Form – Liquid
Strength: 50 % v/v
Do not use ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS or NEGATIVE SKIN TEST CONTROL – GLYCERIN if:
Your healthcare professional has not prescribed it and administered it within their medical office.
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take ALLERGENIC EXTRACTS – POLLENS, ALLERGENIC EXTRACTS – NON-POLLENS or NEGATIVE SKIN TEST CONTROL – GLYCERIN. Talk about any health conditions/circumstances you may have, including:
- Cancer
- Heart Disease
- Female/Male Fertility concerns
Respiratory Issues
- Allergen Sensitivity/Resistance
- Skin irritations
Pregnancy
- Nursing Mother
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines. The following may interact with ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS or NEGATIVE SKIN TEST CONTROL – GLYCERIN:
When discussing with your healthcare professional, make specific reference to the following type of medications:
| Medication Type | Treatment of: |
|---|---|
| Beta Blockers | High blood pressure |
| Dopamine | Low blood pressure, Parkinson’s disease, Cardiac or Kidney function |
Beta2 Agonists Omalizumab/Xolair Oral corticosteroids/Inhalers | Asthma/COPD |
| Prostaglandin D2 Inhibitors | Asthma, allergic rhinitis, and atopic dermatitis |
| Antihistamines | Motion Sickness, nausea or insomnia |
| Histamine2 Antagonists | Gastric ulcers, acid reflux or heart burn |
| Antidepressants | Depression, chronic pain, addiction or mental health conditions |
| Benzodiazepines | Anxiety, insomnia and seizures |
| Topical local anesthetics | Creams or lotions that numb the skin to reduce pain or itching |
| Topical steroids | Inflammatory skin conditions |
| In Vitro Immunoglobulin | In vitro fertilization (IVF) and recurrent pregnancy loss |
| Immunomodulating Biologics | Autoimmune diseases, rheumatoid arthritis, psoriasis, Crohn's disease; oncologic, allergic, rheumatologic, and neurologic conditions |
How to take ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS or NEGATIVE SKIN TEST
CONTROL – GLYCERIN:
- Skin testing is performed by a healthcare professional by placing a drop of specific extract(s), positive skin test control and a negative skin test control on your skin. The healthcare provider will then superficially prick your skin with a sterile needle.
- This process should not make you bleed.
Usual dose:
- A single drop of a specific extract. The amount of extracts tested are based on the history you provide your healthcare professional and their expert recommendation.
Overdose:
- An overdose could occur based on your sensitivity to the extract(s) and in rare instances could result in anaphylactic symptoms. It is imperative that the physician administering your allergenic extracts understand and be prepared for the treatment of severe reactions.
What are possible side effects from using ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT –
NON-POLLENS or NEGATIVE SKIN TEST CONTROL – GLYCERIN?
These are not all the possible side effects you may have when taking ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS or NEGATIVE SKIN TEST CONTROL – GLYCERIN. If you experience any side effects not listed here, tell your healthcare professional.
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |||
|---|---|---|---|---|---|
| Only if severe | In all cases | ||||
| VERY COMMON | |||||
| N/A | |||||
| COMMON | |||||
| N/A | |||||
| RARE | |||||
| Anaphylaxis | X | Seek emergency medical help immediately. | |||
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.
Storage:
This product will be stored at 2-8 °C by your healthcare professional.
Keep out of reach and sight of children.
If you want more information about ALLERGENIC EXTRACT – POLLENS, ALLERGENIC EXTRACT – NON-POLLENS and NEGATIVE SKIN TEST CONTROL – GLYCERIN:
- Talk to your healthcare professional
Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the:
Health Canada website
https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drugproduct-database.html;
Manufacturer’s website
https://www.hsallergy.com/,
Manufacturer’s phone
1-800-992-1120
Last Revised February 2026
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada.html) for information on how to report online, by mail or by fax; or
- Calling toll-free at 1-866-234-2345.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
