Patient Medication Information: uses, side effects, how to take - Pantoprazole for Injection (Teva Canada)
What is PANTOPRAZOLE FOR INJECTION used for?
PANTOPRAZOLE FOR INJECTION is used to treat stomach acid related problems, such as:
Reflux esophagitis.
This is a severe form of heartburn.
Pathological hypersecretory conditions (e.g. Zollinger-Ellison syndrome).
These are conditions in which the stomach produces too much acid.
PANTOPRAZOLE FOR INJECTION is administered:
- mainly in hospitals.
- when you cannot take oral medicines.
- for short-term use (up to 7 days).
How does PANTOPRAZOLE FOR INJECTION work?
PANTOPRAZOLE FOR INJECTION is a proton pump inhibitor. It reduces the amount of acid your stomach makes.
By reducing the acid PANTOPRAZOLE FOR INJECTION reduces the symptoms (e.g. heartburn).
What are the ingredients in PANTOPRAZOLE FOR INJECTION?
Medicinal ingredients: pantoprazole sodium sesquihydrate.
Non-medicinal ingredients: edetate disodium dehydrate and sodium hydroxide.
PANTOPRAZOLE FOR INJECTION comes in the following dosage forms:
- Powder for injection. 40 mg pantoprazole (as pantoprazole sodium sesquihydrate) per vial.
Your healthcare professional may switch you to a tablet (called TEVA-PANTOPRAZOLE). This may occur as soon as you can start taking oral medicines again.
Do not use PANTOPRAZOLE FOR INJECTION if:
You are allergic to any of its ingredients. (See What are the ingredients in PANTOPRAZOLE FOR
INJECTION).
- You are taking rilpivirine.
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take PANTOPRAZOLE FOR INJECTION. Talk about any health conditions or problems you may have, including if you:
are taking other medications (see The following may interact with PANTOPRAZOLE FOR
INJECTION).
are pregnant or plan to become pregnant.
- are breastfeeding or plan to breast feed. Pantoprazole has been found in human breast milk. Talk with your doctor.
- have had any past problems with the amount of zinc in your blood.
suffer these effects:
- severe or persistent diarrhea.
- repeated vomiting.
- vomiting blood.
- dark stools.
- tiredness (anemia).
- difficulty in swallowing.
have low magnesium in the body, which may cause symptoms such as:
- rapid heartbeat.
- dizziness, seizures.
- muscle cramping, twitches or spasms.
- are due to have a specific blood test (Chromogranin A).
Other warnings you should know about:
You will use the lowest dose and shortest time suitable for your condition. Talk to your doctor if you have any concerns about your treatment.
Depending on your condition, your doctor may tell you to use this type of medicine (proton pump inhibitors) for a longer period.
Using proton pump inhibitors for a long time (every day for a year or longer) may increase risks of broken bones of the hip, wrist or spine. Talk to your doctor about this risk.
Long term use of proton pump inhibitors may interfere with the absorption of Vitamin B12 from the diet. This may cause a shortage of Vitamin B12 in your body. Talk to your doctor.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with PANTOPRAZOLE FOR INJECTION:
Warfarin, atazanavir, nelfinavir, saquinavir/ritonavir, methotrexate.
How to take PANTOPRAZOLE FOR INJECTION:
Your doctor or nurse will administer PANTOPRAZOLE FOR INJECTION.
Usual dose:
Your doctor will decide the dose of PANTOPRAZOLE FOR INJECTION for your condition.
The recommended doses are:
| Condition | Adult Dose | How Often |
| Reflux Esophagitis. | 40 mg | Once daily |
| Hypersecretory Conditions. This includes Zollinger-Ellison Syndrome. | 80 mg | Every 12 hours |
Overdose:
In case of drug overdose, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
Missed Dose:
Contact your healthcare professional if you feel your doctor or nurse has missed a dose.
What are possible side effects from using PANTOPRAZOLE FOR INJECTION?
Like all medicines, PANTOPRAZOLE FOR INJECTION may cause side effects. Side effects have generally been mild and did not last a long time. These are not all the possible side effects you may feel when taking PANTOPRAZOLE FOR INJECTION.
The most common side effects are:
- headache.
- diarrhea.
- nausea/vomiting.
- general stomach discomfort.
Less often the following can occur:
- swelling or bruising at the injection site.
- itchiness.
- rash.
Your symptoms may get worse after stopping your medication. This may occur as your stomach may increase the production of acid.
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and call your doctor or pharmacist | |||
| Only if severe | In all cases | ||||
RARE. Disturbances in vision. Most cases reported are not serious. | ✓ | ||||
| ISOLATED CASES. | ✓ | ||||
| Liver damage. Symptoms include a yellow tinge to the skin and eyes. | |||
Serious skin reactions. Symptoms include widespread rash, itching, or hives. Peeling of the skin, blisters on the skin, mouth, nose, eyes and genitals are other symptoms. | ✓ | ||
| Muscle wasting. | ✓ | ||
| Clostridium difficile colitis. Symptoms include severe (watery or bloody) diarrhea, fever, and abdominal pain or tenderness. | ✓ |
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada/adverse-reaction-reporting.html) for information on how to report online, by mail or by fax; or
- Calling toll-free at 1-866-234-2345.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
Storage:
Store at 15°C to 25°C and protect from light.
Keep out of reach and sight of children.
If you want more information about PANTOPRAZOLE FOR INJECTION:
- Talk to your healthcare professional.
Find the full product monograph that is prepared for healthcare professionals and includes this
Patient Medication Information by visiting the Health Canada website (https://health-products.canada.ca/dpd-bdpp/index-eng.jsp); the manufacturer’s website http://www.tevacanada.com; or by calling 1-800-268-4127 ext. 3; or email druginfo@tevacanada.com.