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Potassium Chloride for Injection Concentrate USP: Uses, Side Effects and Dosage

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Source: Health Canada – Drug Product Database (DPD) and product monographs · About this document

Patient Medication Information: uses, side effects, how to take - Potassium Chloride for Injection Concentrate USP

What is Potassium Chloride for Injection Concentrate USP used for?

  • It is used to treat low levels of potassium. It is used when you are not able to take potassium by mouth.

How does Potassium Chloride for Injection Concentrate USP work?

Having a normal level of potassium in your blood is important. It helps your cells, heart, muscles and nerves work properly.

If you are on a potassium-free diet or fasting, you may have a lower than normal level of potassium in your blood. This drug will help raise your potassium levels.

What are the ingredients in Potassium Chloride for Injection Concentrate USP?

Medicinal ingredients: Potassium Chloride

Non-medicinal ingredients: Water for Injection USP.

Potassium Chloride for Injection Concentrate USP comes in the following dosage forms:

Concentrated solution (sterile): 500 mEq / 250 mL (2 mEq / mL)

Serious Warnings and Precautions

  • This drug must be:

    • properly diluted and thoroughly mixed by your doctor, nurse or pharmacy before use.
    • administered with caution and under the supervision of your doctor or nurse.
  • Direct injection of potassium chloride at this concentration may be instantaneously fatal.
  • This drug contains aluminum that may be toxic. It may reach toxic levels with long term use if you have kidney problems.

Do not use Potassium Chloride for Injection Concentrate USP if:

  • Are Allergic to this drug or to any ingredient in the formulation or the components of the container.
  • Have high levels of potassium in your blood
  • Have Kidney failure
  • Have Addison’s disease (a disease of the adrenal gland) and are not being treated for it
  • Have a genetic condition of the adrenal glands
  • Have tissue damage
  • Have a condition in which potassium is not removed from the body
  • Have a condition where you are taking extra potassium and chloride

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Potassium Chloride for Injection Concentrate USP. Talk about any health conditions or problems you may have, including if you:

  • Have diabetes or carbohydrate intolerance
  • Have Heart disease
  • Have Kidney problems
  • Have Problems with your adrenal glands

  • Are Pregnant, or planning on becoming pregnant. It is not known if the drug can cause harm to your unborn baby

  • Are Breastfeeding. It is not known if this drug can pass through your breast milk to

    your baby

Other warnings you should know about:

Laboratory tests: in order to monitor you, your doctor may perform laboratory tests while you are on this treatment.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

The following may interact with Potassium Chloride for Injection Concentrate USP:

  • Medications that increase urination (potassium sparing diuretics).
  • Medications to treat high blood pressure (ACE inhibitors or angiotensin II receptor antagonists).
  • Anticholinergics.

How to take Potassium Chloride for Injection Concentrate USP:

  • This is not a medication that you can use yourself.
  • It will be given into your vein by slow infusion (drip) by your doctor or nurse.
  • The medication will be mixed with other fluids by the pharmacy first before your doctor or nurse gives it to you.

Usual dose:

Your doctor will decide what dose of medication you will receive and for how long. This depends on your medical condition and other factors, such as your weight and the results of your blood tests.

Overdose:

If you think you, or a person you are caring for, have taken too much Potassium Chloride for Injection Concentrate USP, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms.

What are possible side effects from using Potassium Chloride for Injection Concentrate USP?

These are not all the possible side effects you may have when taking Potassium Chloride for Injection Concentrate USP. If you experience any side effects not listed here, tell your healthcare professional.

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Fever
  • Infection at the injection site
  • Formation of a blood clot
  • Inflammation of the vein
  • Pain at the injection site
  • Too much fluid in the blood
  • High levels of potassium (hyperkalemia)
  • Vein irritation
  • Confusion
  • Restlessness
  • Weakness
  • Tingling or prickling sensation (paresthesias) or an inability to move your hands or feet (paralysis)
  • Irregular heart beat
  • Low blood pressure

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Reporting Side Effects

You can report any suspected side effects associated with the use of health products to Health Canada by:

  • Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health products/medeffect-canada/adverse-reaction-reporting.html) for information on how to report online, by mail or by fax; or
  • Calling toll-free at 1-866-234-2345.

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.

If you want more information about Potassium Chloride for Injection Concentrate USP:

  • Talk to your healthcare professional
  • Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html), or by calling 1-800-227-2862.

B. Braun Medical Inc.

824 Twelfth Avenue

Bethlehem, PA 18018-3524 USA

Last Revised: March 21, 2023

Y36-003-065 LD-707-2

About this document

Source: Health Canada – Drug Product Database (DPD) and product monographs · DIN (Drug Identification Number): 02485699

Revision date stated in the text: March 21, 2023

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Potassium Chloride for Injection Concentrate USP

DIN 02485699
Schedule(s) ETHICAL
Active ingredient(s) Potassium chloride 149 MG
Dosage form(s) Solution
Route(s) of administration Intravenous
Drug class (WHO ATC)
  1. B Blood and blood forming organ drugs
    1. B05 Blood substitutes and perfusion solutions
      1. B05X I.V. solution additives
        1. B05XA Electrolyte solutions
          1. B05XA01 Potassium chloride
Company B. BRAUN MEDICAL INC
Current status Marketed
Current status date March 25, 2020

Source: Health Canada – Drug Product Database (DPD) and product monographs, data as of November 1, 2026. Data from the Health Canada Drug Product Database, as published there. Not a substitute for the advice of a doctor or pharmacist.