Patient Medication Information: uses, side effects, how to take - Taro-Rabeprazole EC (Sun Pharma Canada, 10 mg)
What is RAN-RABEPRAZOLE EC used for?
RAN-RABEPRAZOLE EC is used in adults to:
- relieve symptoms and heal duodenal ulcers.
- relieve symptoms and heal stomach ulcers.
heal gastroesophageal reflux disease (GERD) and relieve its symptoms such as:
- the burning feeling that rises from the chest to the throat (heartburn).
- the flow of bitter/sour juice into the mouth (regurgitation).
- treat symptoms of non-erosive reflux disease (NERD) such as heartburn and regurgitation.
- maintain longer term healing of gastroesophageal reflux disease (GERD).
- treat rare conditions where excess acid is produced in the stomach (e.g., Zollinger-Ellison syndrome).
treat ulcers caused by infection with the bacterium, Helicobacter pylori (H. pylori), and prevent these ulcers from coming back by:
- taking RAN-RABEPRAZOLE EC with antibiotics such as amoxicillin and clarithromycin, as directed by your doctor.
- following the information on the antibiotics provided to you by the pharmacist.
How does RAN-RABEPRAZOLE EC work?
RAN-RABEPRAZOLE EC is a medicine called a proton pump inhibitor (PPI). RAN-RABEPRAZOLE EC works by reducing the amount of acid made in your stomach.
What are the ingredients in RAN-RABEPRAZOLE EC?
Medicinal ingredients: rabeprazole sodium
Non-medicinal ingredients: diacetylated monoglycerides, ethylcellulose, FD&C Red #40 aluminum lake, heavy magnesium oxide, hydroxypropyl cellulose, hypromellose phthalate, iron oxide yellow, light magnesium oxide, low-substituted hydroxypropyl cellulose, magnesium stearate, mannitol, propylene glycol, shellac glaze, talc, and titanium dioxide.
RAN-RABEPRAZOLE EC comes in the following dosage forms:
Tablets of 10 mg and 20 mg
Do not use RAN-RABEPRAZOLE EC if you are allergic to:
- rabeprazole or other medications in this class.
- the “nonmedicinal” ingredients in RAN-RABEPRAZOLE EC tablets (see What are the ingredients in RAN-RABEPRAZOLE EC?).
- the antibiotics amoxicillin or clarithromycin if these are used with RAN-RABEPRAZOLE EC to treat ulcers caused by H. pylori.
Do not use RAN-RABEPRAZOLE EC if you are:
- taking rilpivirine
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take RAN-RABEPRAZOLE EC. Talk about any health conditions or problems you may have, including:
- all health problems you have now or have had in the past
- any liver problems
- if you experience symptoms including palpitations (rapid heartbeat), dizziness, seizures, twitching, spasms, muscle weakness, cramps and convulsions. These may be signs of low magnesium levels in your blood
- if you are taking methotrexate
if you are pregnant or planning to become pregnant
- if you are breast-feeding or planning to breast-feed
- if you are due to have a specific blood test (Chromogranin A)
Other warnings you should know about:
Long-term use of RAN-RABEPRAZOLE EC may prevent normal absorption of vitamin B12 from the diet and could lead to vitamin B12 deficiency. Talk to your doctor.
Using RAN-RABEPRAZOLE EC for a long period of time (a year or longer) may increase the risk of fractures of the hip, wrist or spine. Talk to your doctor about your risk.
Using medicines like RAN-RABEPRAZOLE EC for a long period of time may cause a growth in your stomach (polyp). This can lead to intestinal blockage or bleeding. Talk to your doctor if you experience nausea or stomach pain while you are taking RAN-RABEPRAZOLE EC.
Tell your healthcare professional about all the medicines you take, including any drugs (prescription and non-prescription), vitamins, minerals, natural supplements or alternative medicines.
The following may interact with RAN-RABEPRAZOLE EC:
- ketoconazole
- digoxin
- warfarin
- antiretroviral drugs such as atazanavir, nelfinavir, saquinavir
- methotrexate
How to take RAN-RABEPRAZOLE EC:
- Take RAN-RABEPRAZOLE EC exactly as prescribed by your doctor, usually for a specific number of weeks.
- Use the lowest dose and shortest time as determined by your doctor.
- Do not stop taking RAN-RABEPRAZOLE EC even when you start to feel better. If you stop taking RAN-RABEPRAZOLE EC too soon, your symptoms may return.
- Take RAN-RABEPRAZOLE EC with or without meals.
- Swallow tablets whole with a liquid. Do not chew or crush the tablets.
- Talk to your doctor if you have any concerns.
Usual dose:
| Condition | Adult Dose | How often | How long |
| reflux symptoms with esophagitis | 20 mg | once daily | four weeks |
| reflux symptoms without esophagitis, such as heartburn and regurgitation | 10 mg to a maximum of 20 mg | once daily | four weeks |
| duodenal ulcer | 20 mg | once daily | Up to four weeks |
| stomach ulcer | 20 mg | once daily | Up to six weeks |
| ulcer caused by H. pylori infection† | 20 mg | twice daily in combination with antibiotic drugs (clarithromycin and amoxicillin) preferably with the morning and evening meals | one week |
†If you are given RAN-RABEPRAZOLE EC in combination with antibiotic drugs, it is important that you take all medications at the correct time of day and for the entire treatment period to ensure they will work properly. Studies have shown that patients who take their medications as prescribed have better ulcer healing rates and greater success in getting rid of their H. pylori infection.
Overdose:
If you think you have taken too much RAN-RABEPRAZOLE EC, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
Missed Dose:
If you forget to take one dose of RAN-RABEPRAZOLE EC medication, take a tablet as soon as you remember, unless it is almost time for your next dose. If it is, do not take the missed tablet at all. Never double-up on a dose to make up for the one you have missed; just go back to your regular schedule.
What are possible side effects from using RAN-RABEPRAZOLE EC?
Like all medicines, RAN-RABEPRAZOLE EC can cause side effects.
Headache and diarrhea are the most common side effects experienced with RAN-RABEPRAZOLE EC. Less common side effects are rash, itchiness and dizziness. If any of these become troublesome, consult your doctor.
Treatment in combination with antibiotics: If you experience symptoms such as severe diarrhea (bloody or watery) with or without fever, abdominal pain, or tenderness, you may have Clostridium difficile colitis (bowel inflammation). If this occurs, stop taking RAN-RABEPRAZOLE EC and contact your healthcare professional immediately.
If you experience symptoms of low magnesium levels in your body, your doctor may stop RAN-RABEPRAZOLE EC.
Tell your doctor right away if you have any of these symptoms:
- seizures.
- dizziness.
- abnormal or fast heart beat.
- jitteriness.
- jerking movements or shaking (tremors).
- muscle weakness.
- spasms of the hands and feet.
- cramps or muscle aches.
- spasm of the voice box.
- fracture (broken bone).
- New or worsening joint pain.
- Rash on your cheeks or arms that gets worse in the sun.
- Blood in stool.
Stopping your PPI therapy after taking it for a long time, may cause your symptoms to get worse and your stomach may increase acid production. Carefully follow your doctor’s instructions when discontinuing your PPI therapy.
Storage:
Store at room temperature (15º to 25º C) protected from moisture.
Keep out of the sight and reach of children.
If you want more information about RAN-RABEPRAZOLE EC:
- Talk to your healthcare professional.
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website; or by calling 1-866-840-1340.
Ranbaxy Pharmaceuticals Canada Inc.
Brampton, ON
L6T 1C1
Last revised: February 8, 2019
All brands are the property of their respective owners.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |