Teva-Zolmitriptan Od (Teva Canada, 2.5 mg): Uses, Side Effects and Dosage

Serious Warnings and Precautions

• Risk of Heart Attack: Serious heart events including heart attack have been reported within a few hours of starting treatment with TEVA-ZOLMITRIPTAN or TEVA-ZOLMITRIPTAN OD. Do NOT use this medication if you have any form of coronary artery disease.
• Heart Rhythm Problems: Life-threatening instances of heart rhythm disturbances have been reported within a few hours of starting treatment with TEVA-ZOLMITRIPTAN or TEVA-ZOLMITRIPTAN OD. This can be fatal.
• Chest Pain: TEVA-ZOLMITRIPTAN or TEVA-ZOLMITRIPTAN OD may cause chest pain, even in patients without a history of coronary artery disease.
• Risk of Stroke: Bleeding in the brain and stroke have been reported in patients taking medications like TEVA-ZOLMITRIPTAN or TEVA-ZOLMITRIPTAN OD. These conditions can be fatal.

If you think you are experiencing any of the above, contact your healthcare professional or get immediate medical help.

What are TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD used for?

TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD are used in adults to relieve migraine headache and other associated symptoms of a migraine attack.

TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD should not be used to prevent or reduce the number of attacks you experience. Only use TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD to treat an actual migraine headache attack.

How do TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD work?

Migraine headache is believed to be caused by a widening of the blood vessels in the head. TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD narrows these vessels and relieves the pain and other symptoms of migraine headache.

What are the ingredients in TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD?

TEVA-ZOLMITRIPTAN:

Medicinal ingredients: zolmitriptan.

Non-medicinal ingredients: Lactose spray dried, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, and the film coating ingredients are as follows: Iron oxide yellow, macrogol/polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide.

TEVA-ZOLMITRIPTAN OD:

Medicinal ingredients: zolmitriptan.

Non-medicinal ingredients: aspartame, citric acid, colloidal silicon dioxide, corn starch, croscarmellose sodium, lactose monohydrate, mannitol, magnesium stearate, orange flavour, sodium bicarbonate.

TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD come in the following dosage forms:

TEVA-ZOLMITRIPTAN: tablets, 2.5 mg.

TEVA-ZOLMITRIPTAN OD: orally disintegrating tablets, 2.5 mg.

Do not use TEVA-ZOLMITRIPTAN or TEVA-ZOLMITRIPTAN OD if:

• you are allergic to zolmitriptan or any of the other ingredients in TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD (see “What are the ingredients in TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD?”)
• you have a history, or any signs or symptoms of a heart problem or condition
• you have ever had a heart attack or stroke
• you suffer from chest pain, occurring either on exertion or at rest
• you have severe or uncontrolled hypertension
• you are taking or have recently taken (within the last 24 hours) an ergotamine containing or ergot-like drug, or another triptan used to treat migraines
• you are taking or have recently taken (within 2 weeks) a monoamine oxidase inhibitor (MAOI)

• you have another type of headache, that is different from a migraine attack (if you are not sure, ask your healthcare professional). These include:

  • Hemiplegic migraines: these are migraine headaches where you have weakness on one side of your body.
  • Basilar migraines: these are migraine headaches that start in the lower part of the brain.
  • Ophthalmoplegic migraines: these are migraine headaches where you have pain around the eyes.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take TEVA-ZOLMITRIPTAN or TEVA-ZOLMITRIPTAN OD. Talk about any health conditions or problems you may have, including if you:

• have any liver problems

• are at risk of developing heart disease, risk factors include if you:

  • have high blood pressure
  • have high cholesterol
  • are obese
  • have diabetes
  • have a family history of heart disease
  • are a smoker
  • are a postmenopausal female
  • are a male over 40 years of age
• have a condition called Wolff-Parkinson-White syndrome
• have any other allergies or sensitivities
• have a history of epilepsy or structural brain lesions
• have a history of drug use

• are pregnant, think you are pregnant or are planning to become pregnant

• are breastfeeding, or plan to breastfeed
• are over 65 years of age
• have a rare hereditary galactose intolerance such as Lapp lactase deficiency or glucose-galactose malabsorption, because TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD contain lactose.
• have phenylketonuria, because TEVA-ZOLMITRIPTAN OD contains 2.81 mg of phenyl alanine (for TEVA-ZOLMITRIPTAN OD only)

Other warnings you should know about:

Driving and Using Machines: TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD can cause sedation. Avoid driving or using machines until you know how the medication affects you.

Overuse of TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD: As with other migraine treatments, using too much TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD can cause daily headaches or make your migraine headaches worse. Ask your healthcare professional if you think this is the case for you. You may need to stop using TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD to correct the problem.

Risk of Eye Problems: Long-term use of TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD may cause eye problems. If you develop any problems with your eyes, tell your healthcare professional right away.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

The following may interact with TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD:

• medicines used to treat upset stomach or stomach ulcers (such as cimetidine)
• antibiotics from the quinolone family (such as ciprofloxacin)
• oral contraceptives
• propranolol, a beta blocker used to treat heart rhythm problems
• smoking or tobacco
• alcohol
• excessive amounts of green tea or green tea extract
• herbal remedies containing St John’s wort

How to take TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD:

• Take TEVA-ZOLMITRIPTAN / TEVA-ZOLMITRIPTAN OD exactly as your healthcare professional has told you to.

Usual dose:

TEVA-ZOLMITRIPTAN Tablets:

• The usual starting dose is 2.5 mg at the first sign of a migraine attack.
• Swallow the tablet with water.

TEVA-ZOLMITRIPTAN OD Tablets:

• The usual starting dose is 2.5 mg at the first sign of a migraine attack.
• Place the tablet on your tongue and let it dissolve, then swallow.
• Do NOT break the orally disintegrating tablet in half.

If your headache returns and it has been at least 2 hours since you took your first dose, you may take a second dose. The maximum dose is 10 mg in any 24-hour period. If your first dose did not relieve your migraine headache, do not take a second dose without talking to your healthcare professional first.

Overdose:

What are possible side effects from using TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD?

These are not all the possible side effects you may have when taking TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD. If you experience any side effects not listed here, tell your healthcare professional.

• feeling sick
• vomiting
• dizziness
• tiredness
• weakness
• muscle aches and pains
• difficulty swallowing
• dry mouth
• headache
• stomach pain
• increase in the production of urine or in the frequency of urination

Serious side effects and what to do about them

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Reporting Side Effects

Storage:

TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD should be stored at room temperature between 15°C and 30°C.

Do not take your medication after the expiry date on the package and blister foil. If you have any leftover medication that you do not need or is expired, return the tablets to your pharmacist for disposal.

Keep out of reach and sight of children.

If you want more information about TEVA-ZOLMITRIPTAN and TEVA-ZOLMITRIPTAN OD:

• Talk to your healthcare professional.
• Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); the manufacturer’s website http://www.tevacanada.com; or by calling 1-800-268-4127 ext. 3; or email druginfo@tevacanada.com.

Last Revised: JAN 2, 2025