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Zinda-Anastrozole: Uses, Side Effects and Dosage

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Facts
Status:
Prescription (Rx) Current status: Dormant
Strength:
1 mg
Active ingredient:
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Source: Health Canada – Drug Product Database (DPD) and product monographs · About this document

Patient Medication Information: uses, side effects, how to take - Zinda-Anastrozole

ABOUT THIS MEDICATION

What Zinda-ANASTRAZOLE is used for:

Zinda-ANASTROZOLE is used for the treatment of postmenopausal women with hormone receptor positive breast cancer in the following conditions:

  • adjuvant treatment for early breast cancer
  • advanced breast cancer

What Zinda-ANASTROZOLE does:

In hormone sensitive breast cancer, estrogens fuel tumour growth. Following menopause, estrogens are still produced in small amounts in other tissues of the body such as the breasts, muscle and fat. These estrogens are produced when androgens (hormones produced by the adrenal glands) interact with aromatase, a naturally occurring enzyme in the body.

Zinda-ANASTROZOLE belongs to a group of medicines called aromatase inhibitors and works by inhibiting the aromatase enzyme, thereby, suppressing the production of estrogens that can stimulate tumour growth. Suppressing the production of estrogens may help reduce the growth of breast cancer and delay the breast cancer from recurring.

Adjuvant means "in addition to." In early breast cancer, this means that additional treatment is required after primary treatment. The reason for this is that after surgery, a small number of cancer cells may remain in the body. These cells can continue to multiply and spread. Adjuvant therapy is given to prevent or delay these cells from multiplying and spreading. The purpose of adjuvant therapy with Zinda-ANASTROZOLE is to help to delay the breast cancer from recurring. Cytotoxic chemotherapy, radiation, and hormonal treatment are three common forms of adjuvant treatment.

When Zinda-ANASTROZOLE should not be used:

  • If you are allergic to the active ingredient anastrozole or any nonmedicinal ingredients of Zinda-ANASTROZOLE. If you think you may be allergic, ask your doctor for advice.

  • If you are pregnant or breast-feeding.

What the medicinal ingredient is:

Anastrozole

What the nonmedicinal ingredients are:

Croscarmellose sodium, hypromellose, lactose monohydrate, macrogol, magnesium stearate, maltodextrin, and povidone

What dosage forms Zinda-ANASTROZOLE comes in:

Each Zinda-ANASTROZOLE tablet contains 1 milligram of anastrozole.

WARNINGS AND PRECAUTIONS

Serious Warnings and Precautions

  • Zinda-ANASTROZOLE should not be given to premenopausal women.
  • Zinda-ANASTROZOLE should not be given to children.
  • Patients with liver and/or kidney problems, and patients with osteoporosis or at risk for osteoporosis should be carefully monitored by the doctor.
  • Zinda-ANASTROZOLE should be prescribed by a doctor experienced in the use of anti-cancer drugs.

BEFORE you use Zinda-ANASTROZOLE talk to your doctor or pharmacist:

  • If you have any disorder or disease which affects your heart, liver or kidneys.
  • Zinda-ANASTROZOLE lowers the level of female hormones and this may lead to a loss of mineral content of bones, which might decrease their strength and lead to a broken bone. You should talk to your doctor about your osteoporosis risk before using Zinda-ANASTROZOLE.

Zinda-ANASTROZOLE tablets are unlikely to affect your ability to drive a car or to operate machinery. However, some patients may occasionally feel weak or sleepy. If this happens, you should not drive or operate machinery.

INTERACTIONS WITH THIS MEDICATION

BEFORE you use Zinda-ANASTROZOLE talk to your doctor or pharmacist:

  • If you take medicine containing estrogen (a female sex hormone). It may oppose the effect of Zinda-ANASTROZOLE. Some herbal products contain estrogen.
  • If you are currently taking tamoxifen.
  • If you are taking or have recently taken other medicines, even those not prescribed by a doctor.

Please note that these statements may also apply to medicine used some time ago.

PROPER USE OF THIS MEDICATION

Usual dose:

Follow your doctor’s instructions about when and how to take your Zinda-ANASTROZOLE tablets. The usual dose is one tablet once a day. Swallow the tablet with fluids. Try to take your tablet at the same time each day.

For adjuvant treatment of early breast cancer, currently it is recommended that Zinda-ANASTROZOLE be taken for 5 years.

Overdose:

In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

Missed Dose:

Take the last missed dose as soon as you remember, as long as it is at least 12 hours before the next dose is due. If it is less than 12 hours to the next dose, do not take the dose you have missed.

SIDE EFFECTS AND WHAT TO DO ABOUT THEM

Like all medicines, Zinda-ANASTROZOLE can have side effects.

Contact your doctor immediately if any of the following happens to you. You may need further examinations or treatment:

  • Severe skin reactions (Stevens-Johnson syndrome) with lesions, ulcers or blisters. This type of skin reaction is very rare.
  • Allergic reaction with swelling of the face, lips, tongue and/or throat which may cause difficulty in swallowing and/or breathing.
  • Chest pain or angina, as a result of ischemic heart disease (reduced blood flow in the vessels of the heart).
  • Inflammation of the liver (hepatitis). Symptoms may include a general feeling of being unwell, with or without jaundice (yellowing of the skin and eyes) and pain in the upper abdomen on the right side.
  • If you experience nausea, vomiting and thirst, you should tell your doctor. These symptoms may indicate possible increased blood calcium levels.
SERIOUS SIDE EFFECTS, HOW OFTEN THEY HAPPEN AND WHAT TO DO ABOUT THEM
Symptom / effect

Talk with your doctor or pharmacist

In all cases

Stop taking drug and seek immediate emergency medical attention
Very Common (greater than or equal to 10 of every 100 patients are likely to have these events)
Hot flushes✓
Joint pain, joint stiffness or broken bones✓
Common (greater than or equal to 1 of every 100 patients, but less than 10 of every 100 patients, are likely to have these events)
Weakness✓
Carpal tunnel syndrome (tingling, pain, coldness, weakness in parts of the hand)✓
Tickling, tingling or numbness of skin, loss/ lack of taste✓
Vaginal dryness✓
Hair thinning (alopecia)✓
Rash✓
Nausea✓
Diarrhea✓
Headache✓
Changes in blood tests of liver function✓

Bone pain

Muscle pain

✓

✓

Uncommon (greater than or equal to 1 of every 1000 patients, but less than 10 of every 1000 patients, are likely to have these events)
Vaginal bleeding✓
Loss of appetite✓
High blood cholesterol✓
Vomiting✓
Sleepiness/tiredness✓
Trigger finger✓
Hepatitis✓✓
Very Rare (less than 1 of every 10 000 patients are likely to have these events)
Sever skin reactions✓✓
Allergic reactions✓✓

This is not a complete list of side effects. For any unexpected effects while taking Zinda-ANASTROZOLE, contact your doctor or pharmacist.

HOW TO STORE IT

  • Keep out of reach and sight of children.

  • Store at room temperature, 15°C to 30°C. Keep

    container tightly closed.

  • Keep your Zinda-ANASTROZOLE tablets in the
  • original container.
  • Do not use Zinda-ANASTROZOLE after the expiry date on the packaging.

REPORTING SUSPECTED SIDE EFFECTS

You can report any suspected adverse reactions associated with the use of health products to the Canada Vigilance Program by one of the following 3 ways:

  • Report online at www.healthcanada.gc.ca/medeffect
  • Call toll-free at 1-866-234-2345

  • Complete a Canada Vigilance Reporting Form and:

    • Fax toll-free to 1-866-678-6789, or

    • Mail to: Canada Vigilance Program

      Health Canada

      Postal Locator 0701E

      Ottawa, ON K1A 0K9

Postage paid labels, Canada Vigilance Reporting Form and the adverse reactions reporting guidelines are available on the MedEffectTM Canada Website at www.healthcanada.gc.ca/medeffect.

NOTE: Should you require information related to the management of side effects, contact your health professional. The Canada Vigilance Program does not provide medical advice.

MORE INFORMATION

This document plus the full product monograph, prepared for health professionals can be found by contacting the distributor, Zinda Pharma Limited, at

8250 Decarie Suite 110

Montreal, QC H4P 2P5

Last revised: October 10, 2014

About this document

Source: Health Canada – Drug Product Database (DPD) and product monographs · DIN (Drug Identification Number): 02326035

Revision date stated in the text: October 10, 2014

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Zinda-Anastrozole

Rx or OTC
Prescription (Rx)?
DIN 02326035
Schedule(s) PRESCRIPTION
Active ingredient(s) Anastrozole 1 MG
Dosage form(s) Tablet
Route(s) of administration Oral
Drug class (WHO ATC)
  1. L Antineoplastic and immunomodulating agents
    1. L02 Endocrine therapy antineoplastic and immunomodulating agents
      1. L02B Hormone antagonists and related agents
        1. L02BG Aromatase inhibitors
          1. L02BG03 Anastrozole
Company STASON PHARMACEUTICALS INC
Current status Dormant
Current status date September 21, 2017

Source: Health Canada – Drug Product Database (DPD) and product monographs, data as of November 1, 2026. Data from the Health Canada Drug Product Database, as published there. Not a substitute for the advice of a doctor or pharmacist.