Patient Medication Information: uses, side effects, how to take - Allegra-D
What is ALLEGRA-D used for?
ALLEGRA-D sustained-release caplets (capsule-shaped tablets) are indicated for adults and children 12 years of age and older for the effective relief of seasonal allergy symptoms:
- sneezing
- runny nose
- itchy nose / palate / throat
- itchy / watery / red eyes
- and temporary relief of nasal congestion
How does ALLEGRA-D work?
It contains 2 medications: fexofenadine and pseudoephedrine.
Fexofenadine is an antihistamine that helps relieve watery eyes, itchy eyes / nose / throat, runny nose and sneezing.
Pseudoephedrine is a decongestant that helps relieve stuffy nose and nasal or sinus congestion symptoms.
What are the ingredients in ALLEGRA-D?
Medicinal ingredients: fexofenadine hydrochloride and pseudoephedrine hydrochloride
Non-medicinal ingredients: carnauba wax, corn starch, croscarmellose sodium, hydroxypropyl methyl cellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, silicon dioxide and stearic acid.
ALLEGRA-D comes in the following dosage forms:
Sustained-Release Caplets, 60 mg fexofenadine hydrochloride and 120 mg pseudoephedrine hydrochloride
Do not use ALLEGRA-D if:
- you are allergic to fexofenadine hydrochloride, pseudoephedrine or any other ingredients in ALLEGRA-D
- you have severe or uncontrolled high blood pressure
- you have any heart problem
- you at risk of angle closure glaucoma
- you are at risk of urinary retention due to bladder or prostate disorders.
- you are taking or have taken within the past 2 weeks a Monoamine Oxidase inhibitor (MAOI) (such as drugs for depression or Parkinson’s disease)
- you have difficulty in swallowing
- you have a history of seizures
- you use any other vasoconstrictor agents such as nasal decongestants, whether administered orally or nasally
- you have moderate to severe renal impairment (glomerular filtration rate less than 60 mL/min)
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take ALLEGRA-D. Talk about any health conditions or problems you may have, including if you have/are:
- Kidney disease (your doctor should determine if you need a different dose)
- heart disease
- hypertension
- thyroid disease or hyperthyroidism
- increased eye pressure
- prostate problems
- diabetes
pregnant or nursing
- elderly (>65 years)
- history of stroke
- psychosis
Other warnings you should know about:
If nervousness, dizziness, increase in blood pressure, heart palpitations, rapid or irregular heartbeat, neurological symptoms such as onset or worsening of headache or sleeplessness occur, discontinue use and consult the doctor.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with ALLEGRA-D:
- antacid that contains aluminum hydroxide or magnesium hydroxide (e.g. Maalox)
- do not take ALLEGRA-D within 2 hours of taking an antacid that contains aluminum hydroxide or magnesium hydroxide (e.g. Maalox), as these antacids may alter the effectiveness of ALLEGRA-D.
- do not take with fruit juices.
- medicines to treat high blood pressure
- Antimigraine medication
- Methylphenidate
- Tricyclic antidepressants
- P-gp inducers (such as apalutamide)
- do not use ALLEGRA-D caplets with other antihistamines and decongestants.
Usual Dose:
ALLEGRA-D caplets should be swallowed whole with a glass of water on an empty stomach. Do not break or chew the caplet.
Never exceed the recommended dose.
Adults and children 12 years of age and over: Swallow 1 caplet every 12 hours.
Do not give to children under 12 years of age. Patients of 65 years or older should ask a doctor before use of ALLEGRA D.
Avoid prolonged use unless advised by a physician.
The non-medicinal ingredients of ALLEGRA-D may be eliminated in the feces in a form that may resemble the original caplet
Overdose:
| If you think you, or a person you are caring for, have taken too much ALLEGRA-D, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms. |
|---|
Signs of overdose with ALLEGRA-D may include: • dizziness, drowsiness • dry mouth • feeling restless or nervous • vomiting • warmth or tingly feeling, or • seizure (convulsions) • difficulty in breathing • heart palpitations
Missed Dose:
If you missed one or more doses, take the next dose at the next scheduled time and in the normal amount. Do not take two doses at the same time.
What are possible side effects from using ALLEGRA-D?
These are not all the possible side effects you may have when taking ALLEGRA-D. If you experience any side effects not listed here, tell your healthcare professional.
Side effects may include:
- headache
- sleeplessness
- nausea
- dry mouth
- dizziness
- urinating less than usual or not at all.
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
|---|---|---|---|
| Only if severe | In all cases | ||
| RARE | |||
| Overdose: confusion, dizziness, drowsiness, diminished mental alertness, hallucination, tremors or convulsions, coma | ✓ | ||
| Respiratory Difficulty: unusually slow or weak breathing | ✓ | ||
| Allergic Reaction: rash, hypersensitivity reactions with symptoms such as swelling, systemic anaphylaxis | ✓ | ||
| High Blood Pressure: severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure | ✓ | ||
| Fast, Slow or Irregular Heartbeat: heart palpitations. | ✓ | ||
| UNCOMMON | |||
| Sudden severe headaches accompanied by confusion, seizures, vomiting sensation, or changes in vision. These may be signs of a serious condition. | ✓ | ||
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Store caplets at 15-30°C.
Store medication in tightly closed container in a cool, dry place.
Protect from light and moisture.
Keep out of reach and sight of children.
If you want more information about ALLEGRA-D:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html; the manufacturer’s website www.opella.com, or by calling 1-800-636-3664.
Date of Authorization: October 15, 2026