Patient Medication Information: uses, side effects, how to take - Ceftazidime for Injection, USP
What is Ceftazidime for Injection, USP used for?
Ceftazidime for Injection, USP is used to treat the following infections that are proven to be or strongly suspected to be cause by certain bacteria:
- pneumonia (lung infection)
- skin infections
- bladder (urinary tract) infections
- blood infections
- bone infections
- infections around the inner organs (peritonitis)
Antibacterial drugs like Ceftazidime for Injection, USP treat only bacterial infections. They do not treat viral infections such as the common cold. Although you may feel better early in treatment, Ceftazidime for Injection, USP should be taken exactly as directed. Misuse or overuse of Ceftazidime for Injection, USP could lead to the growth of bacteria that will not be killed by Ceftazidime for Injection, USP (resistance). This means that Ceftazidime for Injection, USP may not work for you in the future. Do not share your medicine.
How does Ceftazidime for Injection, USP work?
Ceftazidime for Injection, USP contains a medicine called ceftazidime. Ceftazidime is an antibiotic that kill the bacteria in your body.
What are the ingredients in Ceftazidime for Injection, USP?
Medicinal ingredient: ceftazidime
Non-medicinal ingredient: sodium carbonate
Ceftazidime for Injection, USP comes in the following dosage forms:
Powder for solution
- 1 g / vial
- 2 g / vial
- 6 g / vial
Do not use Ceftazidime for Injection, USP if:
- You are allergic to ceftazidime, cephalosporin antibiotics, or any of the other ingredients in Ceftazidime for Injection, USP. See What are the ingredients in Ceftazidime for Injection, USP?
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Ceftazidime for Injection, USP. Talk about any health conditions or problems you or your child may have, including if you:
- have a history of intestinal problems such as colitis (inflammation of the colon)
- have or develop severe diarrhea as this may be a sign of a more serious condition
- have or have had anemia (low blood iron) after taking antibiotics
- have kidney problems
- are 65 years of age or older
- have had allergic reactions to other medicines such as antibiotics
- are taking any diuretics such as furosemide
- have restrictions on how much sodium you can have
are pregnant, think you could be pregnant, or are planning to become pregnant
- are breastfeeding. Ceftazidime for Injection, USP is excreted into breastmilk.
Other warnings you should know about:
Monitoring and Laboratory Tests: Ceftazidime for Injection, USP may impact the results of blood and urine tests. It may also cause a false-positive reaction for sugar in the urine.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with Ceftazidime for Injection, USP:
- Other antibiotics (such as chloramphenicol)
- Diuretics such as furosemide
- Oral Contraceptives
How to take Ceftazidime for Injection, USP:
- Ceftazidime for Injection, USP will be first mixed into a solution.
- Your healthcare professional will check the solution to make sure it is not cloudy or leaking.
- Ceftazidime for Injection, USP will be given to you by a healthcare professional either as an injection into a vein, infusion (slow drip) through a vein, or as an injection into a muscle.
Usual dose:
The usual dose and how long you are given Ceftazidime for Injection, USP will be different for everyone. Your healthcare professional will decide on the dose that is right for you. Your dose and how often you take it will depend on:
- your age
- the type of infection you have
- how severe your infection is
- other conditions or illnesses you have, including if you have kidney problems
Ask your healthcare professional if you have any questions about how many doses of Ceftazidime for Injection, USP you will need or when you will receive them.
Overdose:
| If you think you have taken too much Ceftazidime for Injection, USP, contact your healthcare professional, hospital emergency department or regional poison control centre immediately, even if there are no symptoms. |
What are possible side effects from using Ceftazidime for Injection, USP?
These are not all the possible side effects you may have when taking Ceftazidime for Injection, USP. If you experience any side effects not listed here, tell you healthcare professional.
Side effects may include:
- swelling, redness, or pain near the injection site
- diarrhea, nausea, vomiting, stomach ache
- white spots in the mouth or throat (yeast infection, thrush)
- vaginal yeast infection (in women)
- headache, dizziness
- flushing (redness)
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
|---|---|---|---|
| Only if severe | In all cases | ||
| COMMON | |||
| Thrombocytopenia (low blood platelets): bruising or bleeding for longer than usual if you hurt yourself, fatigue and weakness. | X | ||
| Pseudomembranous colitis (inflammation of the large intestine): severe diarrhea, usually with blood and mucus, stomach pain and fever. | X | ||
| VERY RARE | |||
| Allergic Reaction: difficulty swallowing or breathing, wheezing, drop in blood pressure, feeling sick to your stomach and throwing up, hives or rash, swelling of the face, lips, tongue or throat. | X | ||
| Nervous System problems: tremors, twitching, seeing things that are not there, tingling. | X | ||
| Seizures (fit): uncontrollable shaking with or without loss of consciousness. | X | ||
| Liver problems: yellowing of the skin and eyes (jaundice), right upper stomach area pain or swelling, nausea or vomiting, unusual dark urine, unusual tiredness. | X | ||
| Hemolytic Anemia (breakdown of red blood cells): pale skin, feeling tired or weak, dizziness, fainting, thirst, rapid breathing. | X | ||
| Infection: fever, high heart rate, feeling unwell, or other signs of new or ongoing infection. | X | ||
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help |
|---|
| Only if severe | In all cases | ||
|---|---|---|---|
| UNKNOWN | |||
| Severe Cutaneous Adverse Reactions (SCAR) (severe skin reactions that may also affect other organs): skin peeling, scaling, or blistering (with or without pus) which may also affect your eyes, mouth, nose or genitals, itching, severe rash, bumps under the skin, skin pain, skin color changes (redness, yellowing, purplish); swelling and redness of eyes or face; flu-like feeling, fever, chills, body aches, swollen glands, cough; shortness of breath, chest pain or discomfort. | X | ||
| Clostridium difficile colitis (bowel inflammation): severe or persistent diarrhea, abdominal pain, nausea and vomiting, fever | X | ||
| Eosinophilia (increased numbers of certain white blood cells): abdominal pain, rash, weight loss, wheezing. | X | ||
| Decreased White Blood Cells: infections, fatigue, fever, aches, pains and flu-like symptoms | X | ||
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Store Ceftazidime for Injection, USP powder at 15 °C to 30 °C. Protect from light.
Keep out of reach and sight of children.
If you want more information about Ceftazidime for Injection, USP:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); the manufacturer's website (https://www.fresenius-kabi.com/en-ca), or by calling 1-877-821-7724.
Fresenius Kabi Canada Ltd.
165 Galaxy Blvd, Suite 100
Toronto, ON M9W 0C8