Patient Medication Information: uses, side effects, how to take - Ceftriaxone for Injection (Fresenius Kabi Canada, 500 mg, ..., 100 G)
What is Ceftriaxone for Injection used for?
Ceftriaxone for Injection is used to treat infections of the:
- brain (meningitis)
- lungs
- abdomen and abdominal wall (peritonitis)
- urinary tract including kidneys
- bones and joints
- skin or soft tissues
- blood
- heart
It is also used:
- to treat gonorrhoea which is a sexually transmitted infection
- to treat bronchitis which is an infection of the chest
- to prevent infections during surgery
Antibacterial drugs like Ceftriaxone for Injection treat only bacterial infections. They do not treat viral infections such as the common cold.
How does Ceftriaxone for Injection work?
Ceftriaxone for Injection is an antibiotic. It belongs to a group of antibiotics called cephalosporins. It works by killing bacteria that cause infections. It does this by preventing them from making their cell walls.
What are the ingredients in Ceftriaxone for Injection?
Medicinal ingredients: ceftriaxone sodium
Non-medicinal ingredients: none
Ceftriaxone for Injection comes in the following dosage forms:
- 10 mL or 15 mL vials containing sterile powder ceftriaxone sodium equivalent to 0.5 g of ceftriaxone, packaged in 25 vials per carton or 10 vials per carton, respectively.
- 10 mL or 15 mL vials containing sterile powder ceftriaxone sodium equivalent to 1 g of ceftriaxone, packaged in 25 vials per carton or 10 vials per carton, respectively.
- 20 mL vials containing sterile powder ceftriaxone sodium equivalent to 2 g of ceftriaxone, packaged in 10 vials per carton.
- 100 mL Pharmacy Bulk Package vials containing ceftriaxone sodium equivalent to 10 grams of ceftriaxone packaged individually.
- 100 grams SmartPak® “Pharmacy Bulk Package” containing sterile powder ceftriaxone sodium equivalent to 100 grams of ceftriaxone.
Do not use Ceftriaxone for Injection if:
- You are allergic to ceftriaxone sodium or any component of the container, other cephalosporins, or penicillins.
- Ceftriaxone for Injection should not be given to newborn babies with certain health conditions.
- Ceftriaxone for Injection should not be given along with intravenous (into a vein) solutions that contain calcium.
Talk to your doctor or nurse before you are given Ceftriaxone for Injection if you:
- have had an allergic reaction in the past, including to a medicine
- have or have had asthma
- have had a condition called hemolytic anemia (loss of red blood cells) after taking an antibiotic
- have kidney problems
- have liver problems
- have or have had gastrointestinal disease (diseases of the stomach or bowels) including colitis (inflammation of the bowels)
- are on a low sodium diet
are pregnant
- are breastfeeding
Other warnings you should know about:
Secondary infections
If you develop new symptoms while you are receiving Ceftriaxone for Injection, talk to your healthcare professional since you may have a second infection.
Other medicines and your kidneys
Tell your healthcare professional if you are taking any other medicines before you receive Ceftriaxone for Injection. It can interact with other medicines that have an effect on your kidneys.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
How to take Ceftriaxone for Injection:
- Ceftriaxone for Injection will be given to you by a healthcare professional
It will be given in one of the following ways:
- as a slow injection into a vein
- as an infusion through a small tube into one of your veins
- as an injection into a large muscle (such as the muscle in your arm)
- Although you may feel better early in treatment, Ceftriaxone for Injection should be used exactly as directed.
- Misuse or overuse of Ceftriaxone for Injection could lead to the growth of bacteria that will not be killed by Ceftriaxone for Injection (resistance). This means that Ceftriaxone for Injection may not work for you in the future.
- Do not share your medicine.
Usual dose:
- Your healthcare professional will decide how much Ceftriaxone for Injection you will receive and for how long you will receive it.
Overdose:
| If you think you, or a person you are caring for, have taken too much Ceftriaxone for Injection, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms |
|---|
What are possible side effects from using Ceftriaxone for Injection?
These are not all the possible side effects you may feel when taking Ceftriaxone for Injection. If you experience any side effects not listed here, contact your healthcare professional.
Side effects may include:
Common:
- diarrhea
- pain or tenderness at the injection site
Uncommon:
- nausea
- vomiting
- altered sense of taste
- dizziness
- headache
- sweating
- malaise
- hot flashes
- swelling of the hands or feet
- tingling, prickling or numbness of the hands or feet
- impaired coordination
Rare:
- stomach pain and cramps
- passing gas
- heartburn
- burning tongue
- nose bleed
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
|---|---|---|---|
| Only if severe | In all cases | ||
| UNCOMMON | |||
| Anaphylactic reactions (allergic reactions): difficulty breathing, fever, hives, itching, rash, swelling of your tongue or throat | ✓ | ||
| Anemia (decreased red blood cells): dizziness, fatigue, loss of energy, shortness of breath, weakness | ✓ | ||
| Oral candidiasis (yeast infection of the mouth): bad taste in the mouth, creamy white bumps on the tongue, cheeks, gums or throat that bleed when scraped, pain, trouble swallowing | ✓ | ||
| Fever or chills | ✓ | ||
| Phlebitis (swelling of a vein): pain, tenderness, redness or swelling of a body area | ✓ | ||
| Skin reaction: Severe skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis and erythema multiforma: blistering, hives, itching blistering, inflamed, peeling, red and dying skin and severe rash | ✓ | ||
| Infection of the vagina, including yeast infection: burning during intercourse or urination, discharge, pain, redness, swelling, vaginal itching | ✓ | ||
| RARE | |||
| Neutropenia (decreased white blood cells): aches, bleeding gums, feeling tired, fever, flu-like symptoms, infections, sore mouth and gums, mouth ulcer, rash | ✓ | ||
| Clostridium difficile colitis (bowel inflammation): severe diarrhea (bloody or watery) with or without fever, abdominal pain, or tenderness | ✓ | ||
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
|---|---|---|---|
| Only if severe | In all cases | ||
| Kidney problems: abdominal or back pain, changes in your urine, confusion, fatigue, irregular heartbeat, nausea, shortness of breath, swelling, weakness. | ✓ | ||
| Liver problems: abdominal pain, dark urine, fatigue, loss of appetite, nausea, vomiting, yellowing of the skin or eyes (jaundice). | ✓ | ||
| Palpitations | ✓ | ||
| Mouth sores | ✓ | ||
| Thrombocytopenia (decreased platelets in the blood); bleeding, bruising, fatigue, weakness. | ✓ | ||
Severe Cutaneous Adverse Reactions (SCAR) (severe skin reactions that may also affect other organs):
| ✓ | ||
| Encephalopathy (brain dysfunction): agitation, change in mental state, confusion, difficulty thinking, disorientation, going in and out of consciousness, hallucinations, sudden involuntary muscle jerks, tremors or twitches | ✓ | ||
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
|---|
Storage:
Store at room temperature (between 15 °C and 30 °C) and protect from light.
Keep out of reach and sight of children.
If you want more information about Ceftriaxone for Injection:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); Fresenius Kabi Canada’s website (http://www.fresenius-kabi.com/en-ca/), or by calling 1-877-821-7724.
Fresenius Kabi Canada Ltd.
165 Galaxy Blvd, Suite 100
Toronto, ON M9W 0C8