Patient Medication Information: uses, side effects, how to take - Cortrosyn Inj 0.25mg
What is CORTROSYN® used for?
Your healthcare professional is using this medicine as part of a diagnostic medical test of the adrenal glands.
Because of the possibility of an allergic reaction CORTROSYN® should only be given under medical supervision.
How does CORTROSYN® work?
CORTROSYN® is a synthetic version of a hormone produced by the pituitary gland that stimulates the adrenal glands to release a hormone called cortisol. CORTROSYN® is used to see how well the adrenal glands are working.
What are the ingredients in CORTROSYN®?
Medicinal ingredients: Cosyntropin
Non-medicinal ingredients: mannitol and water for injection. May contain glacial acetic acid and sodium hydroxide for pH adjustment.
CORTROSYN® comes in the following dosage forms:
Lyophilized powder for injection: 0.25 mg
Do not use CORTROSYN® if you are:
- allergic to corticotrophins
- hypersensitive to this drug or to any ingredient in the formulation
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take CORTROSYN®. Talk about any health conditions or problems you may have, including if you: are pregnant or breastfeeding.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with CORTROSYN®:
- Hydrocortisone
- Estrogen containing products
How to take CORTROSYN®:
A nurse or other healthcare professional will give you this medicine.
An intra-venous (IV) injection is given through an IV line that is put in one of your veins, usually in your arm, wrist, or hand.
An intra-muscular (IM) injection is a shot given in the muscle of your upper arm, thigh, or buttocks.
A blood sample will be taken before the dose of CORTROSYN® is given. Another blood sample will be taken 30 minutes after the dose of CORTROSYN®.
Usual Dose:
Adults
0.25 mg to 0.75 mg given by IV or IM injection.
Children ≤ 2 years of age: A dose of up to 0.125 mg, given by IM injection.
Overdose:
| If you think you have been given too much CORTROSYN®, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms. |
Missed Dose:
If you miss your scheduled administration of the drug, contact your healthcare professional as soon as possible to reschedule your appointment.
What are possible side effects from using CORTROSYN®?
These are not all the possible side effects you may feel when taking CORTROSYN®. If you experience any side effects not listed here, contact your healthcare professional. Please also see Warnings and Precautions.
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
| Only if severe | In all cases | ||
RARE Allergic reaction with symptoms such as redness and pain at the injection site, hives, itchiness, general lack of wellbeing, difficulty breathing | √ | ||
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.
Reporting Side Effects
You can help improve the safe use of health products for Canadians by reporting serious and unexpected side effects to Health Canada. Your report may help to identify new side effects and change the product safety information. 3 ways to report:
Postage paid labels and the Consumer Side Effect Reporting Form are available at MedEffect. NOTE: Contact your healthcare professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Store at 15-30○ C.
Keep out of reach and sight of children.
If you want more information about CORTROSYN®:
Talk to your healthcare professional.
Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website (www.hc-sc.gc.ca); the manufacturer’s website http://www.amphastar.com/, or by calling 1-800-423-4136.