Patient Medication Information: uses, side effects, how to take - Cuvposa
What is CUVPOSA used for?
CUVPOSA is used for reducing drooling caused by certain health problems. It is for patients that are 3-18 years old.
How does CUVPOSA work?
CUVPOSA reduces the rate of drooling. This is done by blocking receptors on the glands that make saliva.
What are the ingredients in CUVPOSA?
Medicinal ingredients: Glycopyrrolate
Non-medicinal ingredients: Citric acid, glycerin, methylparaben, natural and artificial cherry flavour, propylene glycol, propylparaben, purified water, saccharin sodium, sodium citrate, and sorbitol solution.
CUVPOSA comes in the following dosage form:
Oral solution, 1 mg/5 mL.
Do not use CUVPOSA if your child:
- is allergic to glycopyrrolate or any of the other ingredients.
- has an eye problem where the pressure inside the eye is too high (glaucoma).
- has a blockage or backward flow of urine drainage from the kidney, ureter, or bladder.
- has a blockage that keeps food or liquid from passing through the small or large intestine.
- has a blockage in the intestine due to either paralysis or weakening of the intestinal muscles.
- has unstable cardiovascular status.
- has severe ulcerative colitis with or without other serious bowel problems.
- has a disease that makes the voluntary muscles more weak and tired.
- is taking a solid oral form (e.g. a tablet) of potassium chloride.
To help avoid side effects and ensure proper use, talk to your healthcare professional before you give your child CUVPOSA. Talk about any health conditions or problems you may have, including if your child:
- has any stomach or bowel problems, including ulcerative colitis.
- has any problems with constipation.
- has any problems with diarrhea.
- has thyroid problems.
- has high blood pressure.
- has heart problems or abnormal heart beats.
- has a hiatal hernia with gastroesophageal reflux disease (GERD).
- has any problems urinating.
- has any other medical conditions.
is pregnant or plans to become pregnant. It is not known if CUVPOSA can harm an unborn baby.
- is breastfeeding or plans to breastfeed. It is not known if CUVPOSA passes into breast milk and if it can harm the baby.
- has kidney problems.
- has poorly controlled mental conditions and/or seizures.
Other warnings you should know about:
CUVPOSA can cause your child to sweat less. Your child can become overheated. If your child is in an area that is very hot, they may develop heat stroke.
CUVPOSA may cause sleepiness or blurred vision. Your child should not drive a car or operate heavy machinery. Your child should not do other risky activities while taking CUVPOSA.
Tell your healthcare professional about all the medicines your child takes, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with CUVPOSA:
- anticholinergic agents (diphenhydramine, phenothiazines, tricyclic antidepressants)
- amatandine
- atenolol
- cannabinoids (dronabinol, nabilone)
- digoxin
- haloperidol
- levodopa
- metformin
- monoamine oxidase inhibitors (e.g. moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine)
solid oral dosage forms of potassium chloride
If you think you have given your child too much CUVPOSA, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
Ask your healthcare provider or pharmacist if you are not sure if a medicine your child takes is one that is listed above.
How to give CUVPOSA:
Give 1 hour before or 2 hours after meals.
- Give exactly as prescribed by your child’s doctor. Do not change the dose of CUVPOSA unless your doctor tells you to.
- Pour the approximate dose into a specially marked dose measuring cup, then use an oral syringe to accurately measure the correct amount of CUVPOSA. Dosing cups and oral syringes are available at most pharmacies. DO NOT insert the oral syringes into the bottle.
- For questions on how to measure the dose or use an oral syringe, ask your pharmacist or doctor.
- Administer the dose using the oral syringe. Make sure that your child swallows the dose.
- Thoroughly wash the syringe and dose cup with warm water after each use.
- Any unused solution remaining in the dose cup should be discarded after each use.
- The syringe and dose cup should be clean and dry prior to each use.
- Discard 60 days after opening the bottle.
Usual dose:
Your doctor will tell you how much CUVPOSA (millilitres or mLs) to give your child. The usual starting dose is 0.02 mg/kg orally three times daily. Your doctor will adjust the dose over time based on your child’s response and side effects. The maximum recommended dose is 0.1 mg/kg three times daily and should not be greater than 1.5 – 3 mg (7.5 mL – 15 mL) per dose based upon weight.
Overdose:
Missed Dose:
If you miss giving a dose of CUVPOSA to your child and it is:
- within 2 hours of the usual dose time, give your child the missed dose immediately, unless a meal has been eaten within the last 2 hours. Do not feed your child a meal for 1 hour after giving them CUVPOSA.
- more than 2 hours since the usual dose time, do not give your child the missed dose. Give the next dose at the regular dose time.
Do not give your child a double dose to make up for a forgotten dose.
What are possible side effects from using CUVPOSA?
These are not all the possible side effects you may feel when taking CUVPOSA. If you experience any side effects not listed here, contact your healthcare professional. Please also see Other warnings you should know about.
The most common side effects of CUVPOSA include:
- dry mouth.
- vomiting.
- constipation.
- flushing of the face or skin.
- headache.
- problem urinating, difficulty starting urination.
- rapid heart beat.
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
| Only if severe | In all cases | ||
VERY COMMON Constipation:
| X | ||
COMMON Diarrhea:
| X | ||
UNKNOWN Problems with control of body temperature:
| X | ||
Reporting Side Effects
You can help improve the safe use of health products for Canadians by reporting serious and unexpected side effects to Health Canada. Your report may help to identify new side effects and change the product safety information.
3 ways to report:
- Online at MedEffect;
- By calling 1-866-234-2345 (toll-free);
By completing a Consumer Side Effect Reporting Form and sending it by:
- Fax to 1-866-678-6789 (toll-free), or
Mail to: Canada Vigilance Program
Health Canada, Postal Locator 1908C Ottawa, ON
K1A 0K9
Postage paid labels and the Consumer Side Effect Reporting Form are available at MedEffect.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
If your child has a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your child’s daily activities, talk to your healthcare professional.
Storage:
Store at 15°C - 25°C.
Keep CUVPOSA out of reach and sight of children.
If you want more information about CUVPOSA:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website; the manufacturer’s website www.medexus.com or by calling 1-877-633-3987.