Patient Medication Information: uses, side effects, how to take - Magnesium Sulfate Injection, BP 49.3%
What is Magnesium Sulfate Injection, BP 49.3% used for?
Magnesium Sulfate Injection, BP 49.3% is used in adults to:
- prevent seizures associated with pre-eclampsia and eclampsia during pregnancy.
- treat low levels of magnesium in the blood (hypomagnesemia).
How does Magnesium Sulfate Injection, BP 49.3% work?
Magnesium Sulfate Injection, BP 49.3% belongs to a group of medicines called electrolyte solutions. It works by replenishing magnesium in your body. It is a naturally occurring mineral (electrolyte) in your body and is important for many systems in the body, especially the muscles and nerves.
What are the ingredients in Magnesium Sulfate Injection, BP 49.3%?
Medicinal ingredients: Magnesium Sulfate heptahydrate
Non-medicinal ingredients: Water for Injection.
Magnesium Sulfate Injection, BP 49.3% comes in the following dosage forms:
Solution: 493 mg / mL of Magnesium Sulfate heptahydrate
Do not use Magnesium Sulfate Injection, BP 49.3% if:
- you have heart block, a condition where the heart beats more slowly or with an abnormal rhythm.
- you have had a heart attack, or any other conditions in which your heart has been damaged.
- you are allergic to magnesium sulfate or any other ingredients in Magnesium Sulfate Injection, BP 49.3% or its container.
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Magnesium Sulfate Injection, BP 49.3%. Talk about any health conditions or problems you may have, including if you:
are taking the following medicines:
- barbiturates (used to treat anxiety, seizures, and headaches)
- narcotics (used to treat moderate to severe pain)
- hypnotics (used to induce, extend, or improve the quality of sleep) or
- systemic anesthetics (used to make a person sleep throughout a surgery)
- have kidney problems.
- have been told you have high levels of magnesium in your blood.
- have any heart problems, such as an irregular heartbeat, heart failure or heart disease.
Other warnings you should know about:
Aluminum toxicity: Magnesium Sulfate Injection, BP 49.3% contains aluminum, which may reach toxic levels with long term use. This is more likely to happen in people who have kidney problems or in infants.
Pregnancy:
If you are pregnant, your healthcare professional:
- will give you Magnesium Sulfate Injection, BP 49.3%. for the shortest time needed to prevent harm to your unborn baby. Taking Magnesium Sulfate Injection, BP 49.3%.for more than 5 to 7 days may lead to low calcium levels and bone problems in the developing baby or fetus, including thin bones or bone breaks. Your healthcare professional will discuss the potential risks with you.
- will closely monitor your health and that of your baby during your treatment.
- may monitor your blood pressure after each injection.
- Tell your healthcare professional right away if you become pregnant, think you may be pregnant or want to get pregnant during your treatment with Magnesium Sulfate Injection, BP 49.3%.
Effects on newborns: In some cases, babies born to a mother taking Magnesium Sulfate Injection, BP 49.3% during pregnancy have experienced serious problems requiring hospitalization. Be prepared to seek immediate medical help for your newborn if they:
- have difficulty breathing,
- have floppy muscles (like a ragdoll),
- are overly sleepy.
Breastfeeding: Magnesium Sulfate Injection, BP 49.3% can pass into breast milk and may harm a breastfed baby. Talk to your healthcare professional about the best way to feed your baby while you are given Magnesium Sulfate Injection, BP 49.3%.
Check-ups and testing: Your healthcare professional will regularly monitor and assess your health before and while you are taking Magnesium Sulfate Injection, BP 49.3%. This includes blood tests to monitor the level of magnesium in your blood.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with Magnesium Sulfate Injection, BP 49.3%:
- barbiturates (used to treat anxiety, seizures, and headaches)
- narcotics (used to treat moderate to severe pain)
- hypnotics (used to induce, extend, or improve the quality of sleep)
- systemic anesthetics (used to make a person sleep throughout a surgery)
How to take Magnesium Sulfate Injection, BP 49.3%:
Magnesium Sulfate Injection, BP 49.3% will be given to you by a healthcare professional in a hospital or medical office. It will be injected into a muscle or vein.
Usual dose:
Your healthcare professional will decide what dose of medication you will receive and for how long. This will depend on your medical condition and the results of your blood tests.
Overdose:
The symptoms of an overdose with Magnesium Sulfate Injection, BP 49.3% include:
- muscle weakness, loss of tendon reflexes
- low blood pressure, fast, slow or irregular heart rate
- drowsiness, confusion
- respiratory depression (slow and ineffective breathing)
If you think you, or a person you are caring for, have taken too much Magnesium Sulfate Injection, BP 49.3% contact a healthcare professional, hospital emergency department, regional poison control centre or Health Canada’s toll-free number, 1-844 POISON-X (1-844-764-7669) immediately, even if there are no signs or symptoms.
What are possible side effects from using Magnesium Sulfate Injection, BP 49.3%?
These are not all the possible side effects you may have when taking Magnesium Sulfate Injection, BP 49.3%. If you experience any side effects not listed here, tell your healthcare professional.
| Serious side effects and what to do about them | |||
|---|---|---|---|
| Serious side effects and what to do about them | |||
| Symptom / effect | Talk to your healthcare professional | Stop taking this drug and get immediate medical help | |
| Symptom / effect | Talk to your healthcare professional | Stop taking this drug and get immediate medical help | |
| Only if severe | In all cases | ||
| Only if severe | In all cases | ||
| UNKNOWN FREQUENCY | |||
| Hypermagnesemia (high level of magnesium in the blood): flushing, sweating, feeling thirsty, low blood pressure, drowsiness, dizziness, headache, itchy skin, tingling sensation of the skin, nausea, vomiting, confusion, slurred speech, double vision, lack of energy, slow and ineffective breathing, electrolyte imbalances, dehydration, loss of tendon reflexes, muscle weakness, fast, slow or irregular heart rate, coma, heart suddenly stops beating | √ | ||
| Hypocalcemia (low level of calcium in the blood): involuntary contraction of muscles, numbness around the mouth, muscle cramps, burning or prickling sensation of the hands and feet | √ | ||
| Respiratory depression (slow and ineffective breathing): slow, | √ | ||
| shallow or weak breathing, tiredness, confusion, headache, blue lips, fingers, or toes | |||
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting (Canada.ca/drug-device-reporting) for information on how to report online, by mail or by fax; or
- Calling toll-free at 1-866-234-2345.
NOTE: Contact your healthcare professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
Storage:
Store between 15 ͦC and 25 ͦC. Do not freeze.
Keep out of reach and sight of children.
If you want more information about Magnesium Sulfate Injection, BP 49.3%?
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada Drug Product Database website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); the manufacturer’s website www.baxter.ca or by calling 1-888-719-9955.
Baxter and FLEXFLO are trademarks of Baxter International Inc.