Nyda: Uses, Side Effects and Dosage

What is NYDA used for?

• NYDA is used for the physical treatment of scalp hair in case of infestation with head lice (pediculosis capitis).
• If used as instructed, NYDA is also effective against nymphs and eggs (nits).

How does NYDA work?

NYDA solution creeps deeply into the breathing system of the lice, nymphs and eggs resulting in suffocation.

What are the ingredients in NYDA?

Medicinal ingredients: Dimethicone 100 cSt

Non-medicinal ingredients: Alpha-terpineol, boabo oil, jojoba wax, low viscosity dimethicone and medium chain triglycerides.

NYDA comes in the following dosage forms:

Solution, 50% w/w.

Do not use NYDA if:

• NYDA must not be used in people with known hypersensitivity (e.g. allergic reaction) to any of its ingredients

• NYDA should not be used in pregnant or breast-feeding mothers or children under the age of 2.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take NYDA. Talk about any health conditions or problems you may have, including if:

• You are allergic to dimethicones
• You are pregnant or breastfeeding
• You are allergic to any ingredients in NYDA

Other warnings you should know about:

CAUTION: FLAMMABLE:

• Keep away from any open flame or heat source which use an open flame.
• Keep away from sources of ignition and do not smoke while using this product.

When using this product: For external use only.

• You should make sure that NYDA does not come into contact with the eyes or mucous membranes (nose or mouth). If product accidentally gets into the eyes, rinse immediately for 10-15 minutes with water.
• Do not inhale or swallow NYDA.
• NYDA could react with certain hair care and hair tinting products.
• Keep out of reach of children.
• If the infestation recurs or persists after the second application, consult your doctor.
• If skin irritation occurs, discontinue use and contact your doctor.
• Care should be taken when applying this product since it will make hard surfaces such as floors and baths slippery.
• Spillages should be cleaned up immediately.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

The following may interact with NYDA:

There are no drugs that are known to interact with NYDA. Some hair products or hair tinting products may interact with NYDA.

No drug interaction studies have been conducted for NYDA.

How to take NYDA:

Usual dose:

Table 9: Appropriate dosage for adult and/or children (2 years or older).

Directions

Before NYDA is used for the first time, the enclosed dispensing pump must be screwed onto the glass bottle. Always hold the spray bottle upright or the pump will not be able to work properly. Please note that the pump will need to be primed, by pumping, when used for the first time and when it has been unused for a long period.

Before treatment with NYDA

Inspect all scalp hair of each family member or close contacts, with a comb. Treat everyone with lice on the same day to avoid re-infestation. A normal comb can be used before treatment to remove any tangles. This comb should be cleaned thoroughly after use.

According to various Canadian guidelines, additional measures recommended are as follows.

Most household articles in contact with the infested individual, which could harbor the lice and nits, should be examined and appropriately treated. Clothes worn 48 hours prior to treatment, hats, towels and bed linens should be washed in hot water, or dry cleaned, and put in a dry hot setting for 20 minutes or sealed in a plastic bag for 2 weeks, then washed normally.

Items that cannot be washed or dry cleaned, such as mattresses, upholstery, or car seats should be thoroughly vacuumed.

Combs, brushes and other hair care articles can be disinfected by soaking in hot water (above 54°C or 130°F) for 5 to 10 minutes. It is advisable that all members of a family be treated at the same time.

All family members should avoid borrowing personal items (e.g. combs, brushes, hairstyling tools, hats, towels, clothing, etc.) from each other or from friends.

Do not use other topical scalp medications or hair care products while using NYDA.

Treatment with NYDA

NYDA should be applied to dry hair.

1. 1. Wet hair completely with NYDA and leave for 30 minutes.

Apply NYDA to the dry hair close to the scalp. To make sure that an adequate coverage is achieved divide the hair in sections. Pick up hair by sections and carefully spray the roots and scalp of each section. When all sections of the scalp and hair roots have been well coated with NYDA, massage the solution well into the rest of the hair until all the hair including the tips is completely covered.

The amount of NYDA needed depends on the thickness and length of the hair. Make sure that the hair near the scalp and behind the ears is particularly well covered with NYDA, as this is where most lice and nits are found. Leave NYDA on for at least 30 minutes.

1. 2. After 30 minutes, comb hair carefully using a lice comb.

After NYDA has been left on for at least 30 minutes, you may comb the hair carefully with the lice comb to remove the suffocated lice. NYDA makes combing easier because it contains special ingredients which make even long hair very easy to comb.

What is the correct way to use a lice comb for detection and removing of head lice?

Part the hair on the head into several sections and divide each section into fine strands. Comb each strand individually, starting as close to the scalp as possible; i.e. combing from the roots to the tips of the hair. In this way, you can stop the lice from creeping back. Pin back each strand of hair which has been treated with the comb and clean the comb with a paper tissue before continuing.

1. 3. Do not washout! Leave the hair to dry for at least 8 hours (e.g. overnight).

Lice eggs (nits) are very resilient and particularly difficult to remove. Lice stick nits to the hair like strings of tiny white beads. The glue is very resistant and similar in structure to the hair. Even careful combing is not enough to remove all nits from the hair.

You should leave NYDA on the hair for at least 8 hours (e.g. overnight) so that even the most tenacious nits will suffocate.

1. 4. Wash out with normal commercial shampoo.

After a total of at least 8 hours, NYDA can be washed out with your usual shampoo. Any residue of the solution still present after the first wash can be removed easily with a second hair wash.

1. 5. After 8 to 10 days, the treatment must be repeated.

For complete control of head lice and nits, the treatment must be repeated as described above after 8 to 10 days.

Overdose:

In case of oral ingestion, contact a healthcare practitioner (e.g. doctor), hospital emergency department or regional Poison Control Centre, even if there are no symptoms.

Missed Dose:

In case the second treatment (8 to 10 days after the first treatment) was missed, the hair must be checked for live lice. If live lice are found, the treatment as described in 3.2 must be repeated. In case no life lice are found, no further action is required.

What are possible side effects from using NYDA?

• Adverse reactions are not common with NYDA. If any irritation occurs, stop treatment with NYDA.
• Irritation of the eyes can occur with NYDA if they come into contact. Flush with water for 10 to 15 minutes if this occurs.

These are not all the possible side effects you may have when taking NYDA. If you experience any side effects not listed here, tell your healthcare professional.

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Reporting Side Effects

Storage:

Store between 15 °C – 30 °C.

Keep out of reach and sight of children.

If you want more information about NYDA:

• Talk to your healthcare professional

• Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html;

  Or: http://www.nyda.ca

  or by contacting the marketer, Medexus Pharmaceuticals Inc. at: 1-877-630-5674.

Distributed by: Medexus Pharmaceuticals Inc., Verdun, Québec, Canada, H3E 1A2

Last Revised: May 12, 2022