Patient Medication Information: uses, side effects, how to take - Peridex Oral Rinse
What PERIDEX® ORAL RINSE is used for:
- Peridex (0.12% chlorhexidine gluconate) is indicated for use as part of a professional program for the treatment of moderate to severe gingivitis, and for management of associated gingival bleeding and inflammation between dental visits.
How PERIDEX® ORAL RINSE works:
Peridex Oral Rinse (0.12% Chlorhexidine Gluconate) provides antimicrobial activity during oral rinsing which is maintained between rinsings. Rinsing with Peridex inhibits the buildup and maturation of plaque by reducing certain microbes regarded as gingival pathogens, thereby reducing gingivitis. Peridex provided antimicrobial activity during rinsing and for several hours thereafter.
The ingredients in PERIDEX® ORAL RINSE are:
Medicinal ingredient(s): Chlorhexidine gluconate
Non-medicinal ingredients: alcohol, FD&C Blue #1 Dye, glycerine, flavour, PEG-40 sorbitan di-isostearate, saccharin sodium, water
PERIDEX® ORAL RINSE comes in the following dosage form(s):
Peridex oral rinse (0.12% chlorhexidine gluconate) is supplied as a blue liquid in 475 mL amber plastic bottles with child-resistant dispensing closures.
Do not use PERIDEX® ORAL RINSE if:
- persons has a sensitivity to chlorhexidine gluconate
- patients are hypersensitive to this drug or to any ingredient in the formulation, including any non-medicinal ingredient, or component of the container
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take PERIDEX® ORAL RINSE.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
How to take PERIDEX® ORAL RINSE:
- Recommended use is twice daily oral rinsing for 30 seconds, morning and evening after tooth brushing. Peridex is not intended for ingestion and should be expectorated after rinsing. Rinsing the mouth (with water or other mouthwashes), brushing teeth, or eating or drinking should be avoided for about 30 minutes after using Peridex.
Usual dose:
Usual dosage is 15 mL (marked in cap) of undiluted Peridex.
Overdose:
Ingestion of 30 or 60 mL of Peridex (0.12% chlorhexidine gluconate) by a small child (10 kg or less body weight) might result in gastric distress, including nausea, or signs of alcohol intoxication. Medical attention should be sought if more than 120 mL of Peridex is ingested by a small child or signs of alcohol intoxication develop.
| If you think you, or a person you are caring for, have taken too much PERIDEX® ORAL RINSE, contact a healthcare professional, hospital emergency department, regional poison control centre or Health Canada’s toll-free number, 1-844 POISON-X (1-844-764-7669) immediately, even if there are no signs or symptoms. |
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Missed dose:
An occasional missed dose can be ignored if the patient is generally compliant with the prescribed regimen. If you missed a dose of this medication, you do not need to make up the missed dose. Skip the missed dose and continue with your next scheduled dose. Do not take two doses at the same time.
Possible side effects from using PERIDEX® ORAL RINSE:
These are not all the possible side effects you may have when taking PERIDEX® ORAL RINSE. If you experience any side effects not listed here, tell your healthcare professional.
Peridex may cause some tooth discolouration or increases in tartar (calculus) formation, particularly in areas where plaque is more difficult to remove with normal brushing alone. It is important to do a thorough job of cleaning your teeth and to see your dentist at least every six months, or more frequently if your dentist advises.
- Both stain and tartar can be removed by your dentist or hygienist. Peridex may cause permanent discolouration of some front-tooth fillings. To minimize discolouration, you should brush and floss daily, emphasizing areas which begin to discolour. In some cases discolouration may be permanent.
Peridex may taste bitter to some patients and may affect the taste of foods and beverages. This will become less noticeable in most cases with continued use of Peridex. To avoid taste interference, rinse with Peridex after meals. Do not rinse with water or other mouth rinses immediately after rinsing with Peridex.
- For maximum effectiveness avoid rinsing your mouth, brushing your teeth, eating or drinking for about 30 minutes after using Peridex.
Peridex oral rinse should not be used by persons who have a sensitivity to chlorhexidine gluconate. If you develop allergic symptoms such as skin rash, itch, generalized swelling, breathing difficulties, light headedness, rapid heart rate, upset stomach or diarrhea, seek medical attention immediately.
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.
Reporting side effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your healthcare professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Store above freezing (0°C).
If you want more information about PERIDEX® ORAL RINSE:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes the Patient Medication Information by visiting the Health Canada Drug Product Database website (Drug Product Database: Access the database); the manufacturer’s website [ https://www.solventum.com/en-ca/home]; or by calling 1-800-634-2249.
Date of Authorization: 2026-09-04
Solventum and Peridex are trademarks of Solventum. Used under license in Canada. © 2025, Solventum. All rights reserved.