Patient Medication Information: uses, side effects, how to take - Selexid
What is SELEXID® used for?
SELEXID® is used in adults and children above 6 years to treat infection of any part of:
- The bladder
- The kidneys
- The tubes that connect the kidneys to the bladder (ureters)
- The tube that allows the bladder to be emptied (urethra).
Antibacterial drugs like SELEXID® treat only bacterial infections. They do not treat viral infections such as common cold. Although you may feel better earlier in treatment, SELEXID® should be used exactly as directed. Misuse or overuse of SELEXID® could lead to the growth of bacteria that will not be killed by SELEXID® (resistance). This means that SELEXID® may not work for you in the future. Do not share your medicine.
How does SELEXID® work?
Serious Warnings and Precautions
Seek medical help immediately if you notice any of the following serious side effects – you may need urgent medical treatment:
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SELEXID® is a medicine that kills germs in your body.
SELEXID® is an antibiotic that belongs to the penicillin class.
What are the ingredients in SELEXID®?
Medicinal ingredients: pivmecillinam hydrochloride
Non-medicinal ingredients: hydroxypropylcellulose, hypromellose, magnesium stearate, microcrystalline cellulose, simethicone emulsion, synthetic paraffin
SELEXID® comes in the following dosage forms:
SELEXID® is available as tablets in two strengths: 200 mg and 400 mg.
- 200 mg tablets: white, circular film-coated convex tablets with a lion printed on one side and “137” on the other. The tablet is 9.5 mm in diameter.
- 400 mg tablets: A White, capsule-shaped, film-coated tablet, size 8 x 17 mm. There is no embossing on either side.
Do not use SELEXID® if:
- You are allergic to SELEXID® or any of its ingredients
- You are allergic to antibiotic of the penicillin class
- You have a condition that can narrow the tube that carries food and liquid to your stomach (esophagus)
- You have a condition which may reduce the amount of a substance called carnitine in your body. Such conditions include carnitine transporter defect, methylmalonic aciduria and propionic academia.
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take SELEXID®. Talk about any health conditions or problems you may have, including if you:
- Have used SELEXID® recently or for a long time already. SELEXID® may reduce the amount of carnitine in your body if you use it for a longer period.
- Have impaired kidneys.
- Have porphyria (a group of rare disease).
Are pregnant, trying to get pregnant, breast-feeding or planning to breastfeed.
Other warnings you should know about:
WHILE taking SELEXID® contact your doctor or pharmacist if you have:
- watery, bloody stool
- pus or mucus in your stool
- stomach cramps
- Fever
These may be the signs of colitis (an inflammation of the colon). See “Serious side effects and what to do about them” table, below.
Medical Tests:
- Your healthcare professional may order medical tests if you need to take SELEXID for longer periods.
- If you took pivmecillinam just before you gave birth, it may affect the neonatal screening for inherited metabolic disorders and give a false positive result. A ”false positive” means that the test wrongly indicates that your child has the disorder. There is no risk for the newborn, but you should tell your healthcare professional if you took SELEXID® shortly before delivery.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with SELEXID®:
- Probenecid (for gout)
- Methotrexate (for rheumatism, psoriasis or cancer)
- Valproate or valproic acid (for epilepsy)
- Other antibiotic such as erythromycin or tetracycline
How to take SELEXID®:
- Always use SELEXID® exactly as your doctor has told you. Check with your doctor, pharmacist or nurse if you are not sure.
You may take SELEXID® with food.
- Take SELEXID® with at least half a glass of liquid to prevent the tablets from getting stuck in your throat.
Usual dose:
Adults: Acute uncomplicated cystitis and urethritis: 400 mg by mouth 3 times a day for 3 to 7 days.
Children above 6 years and weighing more than 40 kg: The dose depends on the weight of the child. Your doctor will prescribe the right dose for you.
It is very important to take all the medicine that your doctor has told you to take. Finish this medicine even if you feel better. If you stop taking SELEXID® too early or skip doses you may feel ill again.
Overdose:
If you take more SELEXID® than you should, you may get:
- nausea
- vomiting
- stomach pain
- diarrhea
| If you think you, or a person you are caring for, have taken too much SELEXID®, contact a healthcare professional, hospital emergency department, or regional poison control centre immediately, even if there are no symptoms. |
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Missed Dose:
If you forget to take your medicine, take it as soon as you remember. Always take it with at least half a glass of water or other liquid. Then take the next dose at the usual time.
What are possible side effects from using SELEXID®?
These are not all the possible side effects you may have when taking SELEXID®. If you experience any side effects not listed here, tell your healthcare professional.
The most common side effects with use of SELEXID® are:
- fungal infections of the vagina
- diarrhea
- nausea (feeling sick)
Uncommon side effects of SELEXID® are:
- Headache
- Dizziness
- Vomiting
- Stomach pain
- Sore mouth
- Sore or swelling in your food pipe
- Liver problems
- Skin rash, hives
- Itching
- Fatigue
- Low amount of carnitine in your body. This may cause muscle pain, tiredness and confusion
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help | |
|---|---|---|---|
| Only if severe | In all cases | ||
| RARE | |||
| Allergic reactions: difficulty breathing, swelling of the face or throat, severe skin rash, sudden swelling | X | ||
| Pseudomembranous colitis: watery, bloody stool, pus or mucus in your stool, stomach cramps, fever | X | ||
| UNKNOWN | |||
Severe Cutaneous Adverse Reactions (SCAR) (severe skin reactions that may also affect other organs): skin peeling, scaling, or blistering (with or without pus) which may also affect your eyes, mouth, nose or genitals; itching; severe rash; bumps under the skin; skin pain; skin color changes (redness, yellowing, purplish); swelling and redness of eye or face; flu-like feeling, fever, chills, body aches, swollen glands, cough; shortness of breath, chest pain or discomfort | X | ||
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Store at 15-30 °C.
Do not use SELEXID® after the expiry date on the label (EXP).
Keep out of reach and sight of children.
If you want more information about SELEXID®:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website: (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html; or by contacting the sponsor, Karo Healthcare AB, at medinfoca@karo.com, or by calling 1-800-780-6649.