Patient Medication Information: uses, side effects, how to take - Spy Agent Green Kit for Spy Elite
What is SPY AGENT™ GREEN used for?
SPY AGENT GREEN is used with the SPY Elite or Pinpoint medical devices while you are having surgery to help your doctor to see:
- blood flow into your tissues and organs,
- bile ducts, found outside your liver, or
- lymph nodes and lymph vessels during the treatment of uterine or cervical cancer.
How does SPY AGENT™ GREEN work?
SPY AGENT GREEN is a fluorescent dye that lights up, when a certain light is shone on it. By giving you SPY AGENT GREEN, your doctor will be able to see inside your body using specialized imaging equipment.
What are the ingredients in SPY AGENT™ GREEN?
Medicinal ingredients: Indocyanine green
Non-medicinal ingredients: Sodium iodide
SPY AGENT™ GREEN comes in the following dosage forms:
SPY AGENT GREEN is supplied as a single use vial containing 25 mg of a freeze-dried powder. Each vial of SPY AGENT GREEN can only be used during one surgical procedure in one patient.
Do not use SPY AGENT GREEN if:
- you are allergic to indocyanine green or sodium iodide.
- you have a history of allergy to iodides because of the risk of a severe allergic reaction (anaphylaxis).
To help avoid side effects and ensure proper use, talk to your healthcare professional before you are given SPY AGENT GREEN. Talk about any health conditions or problems you may have, including if you:
are sensitive to iodides or iodinated imaging agents
are pregnant or planning to become pregnant
- are breastfeeding or planning to breastfeed
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with SPY AGENT™ GREEN:
- sodium bisufite, including some heparin products
How to take SPY AGENT™ GREEN:
Your healthcare professional will give the SPY AGENT GREEN to you in the operating room either before or during your surgery.
Usual dose:
Your doctor will determine how much SPY AGENT GREEN you will be given. Depending on your surgical procedure, you will be given the following amounts of SPY AGENT GREEN:
- For seeing blood flow to and within tissues and organs, an injection in your vein of 1.25 mg to 5.0 mg.
- For seeing bile ducts, an injection in your vein of 2.5 mg.
- For seeing lymph nodes, tan injection in your cervix of 4 mg.
Overdose:
| If you think you have been given too much SPY AGENT GREEN, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms. |
What are possible side effects from using SPY AGENT™ GREEN?
These are not all the possible side effects you may feel when given SPY AGENT GREEN. If you experience any side effects not listed here, contact your healthcare professional.
Serious side effects and what to do about them
| Symptom / effect | Talk to your healthcare professional | Stop taking drug and get immediate medical help |
| Only if severe | In all cases | |
RARE Allergic Reaction (hypersensitivity reaction): possibly life threatening dizziness, severe itching, hives, nausea, difficulty breathing, rash, low blood pressure | ||
| √ | √ | |
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Store at room temperature, 20° to 25°C.
Keep out of reach and sight of children.
If you want more information about SPY AGENT™ GREEN:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website (http://hc-sc.gc.ca/index-eng.php); the manufacturer’s website www.stryker.com, or by calling 1-800-324-4422.