Patient Medication Information: uses, side effects, how to take - Ssp+
What is SSP+ used for?
SSP+ is a solution designed to
- Be used by a healthcare professional to partially replace plasma in the preparation and storage of platelets concentrates obtained either by buffy coat pooling or by apheresis device.
- Enable platelets to be stored in a mix of SSP+ and plasma at 20°C - 24°C, under gentle agitation, for up to 7 days following collection and according to local regulations.
How does SSP+ work?
SSP+ provides the appropriate components to maintain the platelet function during storage. SSP+ alone is not intended for direct intravenous infusion and does not, by itself, have any therapeutic effects. SSP+ acts to provide the appropriate environment and nutrients to maintain platelets function and thus their storage.
What are the ingredients in SSP+?
Medicinal ingredients are:
Disodium phosphate anhydrous, Magnesium chloride hexahydrate, Potassium chloride, Sodium acetate trihydrate, Sodium chloride, Sodium citrate dihydrate, Sodium dihydrogen phosphate dihydrate, Water for injection.
Nonmedicinal ingredients are: none.
SSP+ comes in the following dosage forms:
SSP+ is supplied as a sterile solution containing:
- Disodium phosphate anhydrous 3.05g/L,
- Magnesium chloride hexahydrate 0.30 g/L,
- Potassium chloride 0.37 g/L,
- Sodium acetate trihydrate 4.42 g/L,
- Sodium chloride 4.05 g/L,
- Sodium citrate dihydrate 3.18 g/L,
- Sodium dihydrogen phosphate dihydrate 1.05 g/L,
- Water for injection, quantity sufficient to achieve 1000mL.
SSP+ is packaged in plastic bags designed for two collection methods of platelets:
- ❖ Buffy coat production method: 250 mL, 280 mL, 300 mL
- ❖ Apheresis method: 280 mL, 300 mL, 500 mL
Do not use SSP+ if:
You are allergic to one or more components.
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take SSP+. Talk about any health conditions or problems you may have, including if:
You are taking potassium-containing food or medications.
Other warnings you should know about:
SSP+ alone is NOT FOR DIRECT INTRAVENOUS INFUSION.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
How to take SSP+
SSP+ alone should not be infused directly.
SSP+ is used to replace a portion of the plasma to store platelets concentrates. It is used in the preparation and storage of platelets concentrates units by the methods of buffy coats (4 to 6 buffy coats bags will constitute a platelets concentrate unit) or apheresis device. The solution should be prescribed and administration of platelets should be established only by a healthcare professional qualified in the transfusion field.
Usual dose:
Platelets concentrates are stored in a mix of SSP+ and plasma at a ratio of up to 80%SSP+/20% plasma.
Overdose:
Your fluid balance, electrolyte and acid-base balance will be carefully monitored during transfusion.
Multiple transfusions of platelet additive solution E may lead to overdosage of potassium and magnesium.
If you have any further questions on the use of this product, please ask your doctor or pharmacist.
What are possible side effects from using SSP+?
There are no known side effects with the use of SSP+.
If you have a troublesome symptom or side effects that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.
REPORTING SIDE EFFECTS
You can report any suspected side effects associated with the use of health products to Health Canada by:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Keep out of reach and sight of children.
SSP+ should be stored between 15°C to 30°C.
SSP+ platelets concentrates units should be stored between 20°C and 24°C under gentle agitation up to 7 days after collection and according to local regulation.
If you want more information about SSP+:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website (http://hc-sc.gc.ca/index-eng.php); the manufacturer’s website https://www.macopharma.com/ or by calling 1-514-868-2222.