Fosfomycin Powder for Oral Solution: Uses, Side Effects and Dosage

What is Fosfomycin powder for oral solution used for?

Fosfomycin powder for oral solution is an antibiotic medicine used in adult women to treat urinary tract infections.

Antibacterial drugs like Fosfomycin powder for oral solution treat only bacterial infections. They do not treat viral infections. Fosfomycin powder for oral solution should be used exactly as directed. Misuse or overuse of Fosfomycin powder for oral solution could lead to the growth of bacteria that will not be killed by Fosfomycin powder for oral solution (resistance). This means that Fosfomycin powder for oral solution may not work for you in the future. Do not share your medicine.

How does Fosfomycin powder for oral solution work?

Fosfomycin powder for oral solution is an antibiotic that kills the bacteria causing the infection. Fosfomycin powder for oral solution starts working to kill bacteria within hours after taking it. The bladder irritation caused by the bacteria and the symptoms that you may be feeling can last for a short time even after the bacteria have been killed.

What are the ingredients in Fosfomycin powder for oral solution?

Medicinal ingredient: fosfomycin tromethamine (equivalent to 3g of fosfomycin)

Non-medicinal ingredients: mandarin and orange flavouring, saccharin, sucrose.

Fosfomycin powder for oral solution comes in the following dosage forms:

Single Dose Sachet: 3 g of powder

Do not use Fosfomycin powder for oral solution if:

• you are allergic (hypersensitive) to fosfomycin or to any ingredient in this formulation (see What are the ingredients in Fosfomycin powder for oral solution?).

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Fosfomycin powder for oral solution. Talk about any health conditions or problems you may have, including if you:

• have kidney problems or are undergoing hemodialysis;
• have an intolerance to some sugars as Fosfomycin powder for oral solution contains sucrose;

• are pregnant or planning to become pregnant;

• are breastfeeding or planning to breastfeed;

Other warnings you should know about:

Fosfomycin powder for oral solution is not related to penicillin or other antibiotics that commonly cause allergic reactions. If you have a history of allergy to antibiotics, inform your doctor before taking Fosfomycin powder for oral solution. Allergic reactions to Fosfomycin powder for oral solution have been reported. Do not take Fosfomycin powder for oral solution if you have previously had an allergic reaction to it.

Ability to Drive and Use Machine: Dizziness has been reported from some patients taking Fosfomycin powder for oral solution which may affect your ability to drive and operate machinery. Do not drive or operate machines until you know how you respond to Fosfomycin powder for oral solution.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

The following may interact with Fosfomycin powder for oral solution:

• probenecid used to treat gout
• metoclopramide hydrochloride used to treat digestive problems

How to take Fosfomycin powder for oral solution:

1. 1.

   It is recommended that Fosfomycin powder for oral solution be taken on an empty stomach or at least 2-3 hours after a meal.

2. 2. Empty entire contents of Fosfomycin powder for oral solution sachet into about 125 mL (½ cup) of cold water and stir to dissolve.
3. 3. Take immediately after dissolving in water, making sure to drink the complete contents of the glass.

One sachet of Fosfomycin powder for oral solution is a complete therapy for treating your bladder infection. Since Fosfomycin powder for oral solution is eliminated in urine over a period of three days, the bacteria in the bladder are killed by Fosfomycin powder for oral solution during this period of time. You should see complete relief or improvement in your symptoms within 2 to 3 days. If your symptoms do not improve by the fourth day, you should contact your healthcare professional.

Usual adult dose:

The usual dose of Fosfomycin powder for oral solution is one single dose sachet.

Overdose:

Missed Dose:

Fosfomycin powder for oral solution treatment consists of a single dose. If you did not take your dose at the prescribed time, take it on an empty stomach or at least 2-3 hours after your next meal.

What are possible side effects from using Fosfomycin powder for oral solution?

These are not all the possible side effects you may feel when taking Fosfomycin powder for oral solution. If you experience any side effects not listed here, contact your healthcare professional.

Side effects may include:

• abdominal pain, nausea, upset stomach
• back pain
• diarrhea
• dizziness
• headache
• runny nose
• rash
• vaginal infection
• weakness

Serious side effects and what to do about them

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.

Reporting Side Effects

Storage:

Store at 15°C -30°C.

Do not use after the expiration date printed on the box.

Keep out of reach and sight of children.

If you want more information about Fosfomycin powder for oral solution:

• Talk to your healthcare professional
• Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by visiting the Health Canada website (https://www.canada.ca/en/health-canada. html); the manufacturer’s website www.parlabscanada.com , or by calling 1-877-894-6532.

Last Revised June 13, 2019