Jamp Tobramycin / Dexamethasone: Uses, Side Effects and Dosage

What is JAMP Tobramycin / Dexamethasone used for?

JAMP Tobramycin / Dexamethasone is used to treat inflammatory conditions of the eye where there is or may also be an eye infection.

Some of the conditions JAMP Tobramycin / Dexamethasone may be used to treat include:

• Chronic inflammation of the uvea (a structure of the eye, including the iris i.e. the coloured part of the eye).
• Eye injuries caused by chemicals, radiation or heat burns.
• Eye injuries caused by foreign objects.

Antibacterial drugs like JAMP Tobramycin / Dexamethasone treat only bacterial infections. They do not treat viral infections. Although you may feel better early in treatment, JAMP Tobramycin / Dexamethasone should be used exactly as directed. Misuse or overuse of JAMP Tobramycin / Dexamethasone could lead to the growth of bacteria that will not be killed by JAMP Tobramycin / Dexamethasone (resistance). This means that JAMP Tobramycin / Dexamethasone may not work for you in the future. Do not share your medicine.

How does JAMP Tobramycin / Dexamethasone work?

JAMP Tobramycin / Dexamethasone contains:

• Dexamethasone, a corticosteroid.
• Tobramycin, an aminoglycoside antibiotic.

Dexamethasone blocks some substances that inflame the body. Tobramycin blocks bacterial growth and reduces infections. Together, they treat the eye.

What are the ingredients in JAMP Tobramycin / Dexamethasone?

Medicinal ingredients: Tobramycin 0.3% w / v and dexamethasone 0.1% w / v

Non-medicinal ingredients:

Preservative: Benzalkonium chloride 0.01% w / v

Others: Edetate disodium dihydrate, hydroxyethyl cellulose, sodium chloride, sodium hydroxide (to adjust pH), sodium sulfate, sulfuric acid (to adjust pH), tyloxapol and water for injection.

JAMP Tobramycin / Dexamethasone comes in the following dosage forms:

Eye drop suspension

Do not use JAMP Tobramycin / Dexamethasone if you:

• Are allergic (hypersensitive) to tobramycin, dexamethasone or any of the other ingredients in JAMP Tobramycin / Dexamethasone (see What are the ingredients in JAMP Tobramycin / Dexamethasone?).
• Are allergic to other aminoglycoside antibiotics.
• Have herpes simplex keratitis (inflamed cornea of the eye caused by the herpes simplex virus).
• Have smallpox, chickenpox or any other viral infection of the eye.
• Have a fungal infection of the eye.
• Have a parasitic infection of the eye.
• Have a mycobacterial infection of the eye, including tuberculosis.
• Have an active untreated eye infection.
• Recently had a simple removal of an object from the eye.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take JAMP Tobramycin / Dexamethasone. Talk about any health conditions or problems you may have, including if you:

• Have used other corticosteroids before in the past.
• Develop an allergic reaction. Signs may include skin redness, itching and rash. You should stop taking JAMP Tobramycin / Dexamethasone.
• Are taking another aminoglycoside antibiotic.
• Have or if you have ever had conditions such as myasthenia gravis or Parkinson’s disease. Antibiotics of this kind may worsen muscle weakness.
• Develop an eye infection or your infection gets worse. You should stop taking JAMP Tobramycin / Dexamethasone.
• Have problems with your metabolism. Talk to your doctor if you experience swelling and weight gain around the trunk and in the face as these are usually the first signs of problems with your metabolism. This risk is especially important in patients treated with medicines containing ritonavir or cobicistat, medicines used in the treatment of HIV.
• Are taking a nonsteroidal anti-inflammatory drug (NSAID). Taking JAMP Tobramycin / Dexamethasone and an NSAID at the same time may slow healing of the eye.
• Have diabetes. You may be at a higher risk of developing increased pressure in the eyes, vision problems or cataracts.
• Have a disease causing thinning of the eye. Small tears (perforations) have occurred.
• Wear contact lenses. Contact lens wear is not recommended during treatment of eye inflammation or an eye infection.

• Are pregnant, may be pregnant or planning to become pregnant.

• Are breastfeeding or planning to breastfeed.

• Are under 18 years of age. JAMP Tobramycin / Dexamethasone has not been tested in children under 18 years of age.

Other warnings you should know about:

Taking JAMP Tobramycin / Dexamethasone for a long time increases the risk of developing:

• High eye pressure.
• Glaucoma.
• Vision problems.
• Cataracts.
• An eye infection.
• Problems with your metabolism. Talk to your doctor if you experience swelling and weight gain around the trunk and in the face as these are usually the first manifestations of the syndrome. These risks are especially important in patients treated with medicines containing ritonavir or cobicistat.

Your doctor should check your eye pressure regularly.

JAMP Tobramycin / Dexamethasone contains the preservative benzalkonium chloride. This can cause eye inflammation, including inflammation and damage to the cornea. Benzalkonium chloride discolours soft contact lenses. It is best not to wear contact lenses while you are using JAMP Tobramycin / Dexamethasone. If you must wear contact lenses, remove them before applying JAMP Tobramycin / Dexamethasone and wait at least 15 minutes before putting your lenses back in.

Your vision may become blurry right after using JAMP Tobramycin / Dexamethasone. Do not drive or use machines until your vision clears.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

Drug interaction studies have not been done with JAMP Tobramycin / Dexamethasone.

The following may interact with JAMP Tobramycin / Dexamethasone:

• Nonsteroidal anti-inflammatory drugs (NSAIDs).
• Ritonavir or cobicistat (medicines used in the treatment of HIV).

How to take JAMP Tobramycin / Dexamethasone:

SHAKE WELL BEFORE USE.

After removing the cap: if the security snap collar is loose, remove it before using

JAMP Tobramycin / Dexamethasone.

Usual adult dose:

1 to 2 drops in the conjunctival sac of the affected eye(s) every 4 hours. During the first 24 to 48 hours, 1 to 2 drops can be applied every 2 hours. As your condition improves, you may reduce the frequency as directed by your doctor or pharmacist.

How to use:

1 2

1. 1. Wash your hands.
2. 2. Get the JAMP Tobramycin / Dexamethasone bottle and a mirror.
3. 3. Shake well before use.
4. 4. Hold the bottle, pointing down, between your thumb and fingers.
5. 5. Tilt your head back.
6. 6. Pull down your lower eyelid with a clean finger until there is a “v” pocket between your eyelid and your eye. The drop will go in here (picture 1).
7. 7. Bring the bottle tip close to the eye. Do this in front of a mirror if it helps.
8. 8. Do not touch your eye, eyelid, surrounding areas or other surfaces with the dropper, to avoid contaminating the suspension.
9. 9. Gently press on the base of the bottle to release one drop at a time. Do not squeeze the bottle. It is designed so that a gentle press on the bottom is all that it needs (picture 2).
10. 10. If you miss, wipe up and try again.
11. 11. Close the bottle immediately after use.

If your doctor has prescribed other eye drop or ointment medicines to be used along with JAMP Tobramycin / Dexamethasone, apply each medicine at least 5 minutes apart.

Eye ointments should be administered last.

Overdose:

If you apply too much JAMP Tobramycin / Dexamethasone, rinse it out with warm water. Do not apply more JAMP Tobramycin / Dexamethasone until it is time for your next regular dose.

Missed Dose:

If you forget to take JAMP Tobramycin / Dexamethasone, take it as soon as you remember. However, if it is close to your next regular dose, skip your missed dose and follow your regular schedule. Do not use a double dose to make up the missed dose.

What are possible side effects from using JAMP Tobramycin / Dexamethasone?

These are not all the possible side effects you may feel when taking JAMP Tobramycin / Dexamethasone. If you experience any side effects not listed here, contact your healthcare professional. Please also see WARNINGS AND PRECAUTIONS in the Product Monograph.

Possible side effects include:

• Eyelid redness or swelling
• Increased tearing
• Pupil dilation
• Dry eye
• Eye allergy
• Eye irritation, pain, itching, inflammation, discomfort or redness
• Blurred vision
• Upset stomach, nausea or metallic taste in the mouth
• Dizziness
• Headache
• Abdominal discomfort
• Skin itching or rash
• Eyelid drooping

Serious side effects and what to do about them

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional.

Reporting side effects

Storage:

Store in an upright position at room temperature (between 15-30°C).

Discard unused portion at end of treatment or 28 days after opening the bottle.

Keep out of reach and sight of children.

If you want more information about JAMP Tobramycin / Dexamethasone:

• Talk to your healthcare professional
• Find the full Product Monograph that is prepared for healthcare professionals and includes the Patient Medication Information by visiting the Health Canada Drug Product Database website (https://www.canada.ca/en/health- canada/services/drugs-health-products/drug-products/drug-product-database.html); or by calling 1-866-399-9091.

1310 rue Nobel

Boucherville, Québec

J4B 5H3, Canada

Last Revised: Sept. 1, 2026