Patient Medication Information: uses, side effects, how to take - Periogard (Colgate-Palmolive Canada, PM 00040779)
What is chlorhexidine gluconate 0.12% oral rinse used for?
- Treatment of moderate to severe gingivitis and management of associated gingival bleeding and inflammation between dental visits.
How does chlorhexidine gluconate 0.12% oral rinse work?
Chlorhexidine gluconate 0.12% oral rinse provides antimicrobial activity during oral rinsing which is maintained between rinsings. Microbiologic sampling of plaque has shown a general reduction of both aerobic and anaerobic bacterial counts ranging from 54-97% through six months’ clinical use. Rinsing with chlorhexidine gluconate 0.12% oral rinse inhibits the buildup and maturation of plaque by reducing certain microbes regarded as gingival pathogens, thereby reducing gingivitis.
What are the ingredients in chlorhexidine gluconate 0.12% oral rinse?
Medicinal ingredients: Chlorhexidine gluconate
Non-medicinal ingredients: Alcohol, FD&C Blue # 1, flavour, glycerine, PEG-40 sorbitan diisostearate, saccharin sodium, USP purified water.
Chlorhexidine gluconate 0.12% oral rinse comes in the following dosage forms: Chlorhexidine gluconate 0.12% oral rinse is supplied as a blue liquid in 1-oz (15-mL) and 16- ounce (473-mL) amber bottles.
Do not use chlorhexidine gluconate 0.12% oral rinse if:
- You have any allergies to this drug or its ingredients or components of the container (Contraindications).
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take chlorhexidine gluconate 0.12% oral rinse. Talk about any health conditions or problems you may have, including if you:
- Have allergies to this drug or its ingredients or components of the container
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
Usual dose:
Usual dose is 15-mL of undiluted chlorhexidine gluconate 0.12% oral rinse used twice daily for oral rinsing for 30 seconds. Chlorhexidine gluconate 0.12% oral rinse is not intended for ingestion and should be expectorated after rinsing.
Overdose:
Ingestion of 30 or 60 mL of chlorhexidine gluconate 0.12% oral rinse by a small child (10 kg or less in body weight) might result in gastric distress, including nausea, or signs of alcohol intoxication. Medical attention should be sought if more than 120 mL of chlorhexidine gluconate 0.12% oral rinse is ingested by a small child or if signs of alcohol intoxication develop.

If you think you have taken too much chlorhexidine gluconate oral rinse, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
Missed Dose:
An occasional missed dose can be ignored if the patient is generally compliant with the prescribed regimen.
What are possible side effects from using chlorhexidine gluconate 0.12%
oral rinse?
The most common side effects associated with chlorhexidine gluconate 0.12% oral rinse are (1) an increase in staining of oral surfaces, (2) an increase in supragingival tartar (3) an alteration in taste perception to which most patients accommodate.
These are not all the possible side effects you may feel when taking chlorhexidine gluconate 0.12% oral rinse. If you experience any side effects not listed here, contact your healthcare professional. Please also see Warnings and Precautions.
If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, talk to your healthcare professional
Reporting Side Effects
You can help improve the safe use of health products for Canadians by reporting serious and unexpected side effects to Health Canada. Your report may help to identify new side effects and change the product safety information. 3 ways to report:
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. |
Storage:
Preserve in tight containers, protected from light, at controlled room temperature (15°C to 30°C).
Keep out of reach and sight of children.

If you want more information about chlorhexidine gluconate 0.12% oral rinse:
- Talk to your healthcare professional
- Find the full product monograph that is prepared for healthcare professionals and includes this Patient Medication Information by calling 1-800-268-6757.
Colgate-Palmolive Canada Inc . Two Morneau Shepell Centre, 5th Floor, 895 Don Mills Road, Toronto, Ontario M2N 1G5
Last Prepared: August 17, 2017

