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Travasol: Uses, Side Effects and Dosage

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Source: Health Canada – Drug Product Database (DPD) and product monographs · About this document

Patient Medication Information: uses, side effects, how to take - Travasol

ABOUT THIS MEDICATION

What the medication is used for:

TRAVASOL E (amino acids WITH electrolytes injection) and TRAVASOL (amino acids injection) are intravenous nutritive supplements used to provide nutrition through a tube into a vein when normal feeding by mouth is not possible or suitable.

TRAVASOL E / TRAVASOL product must only be used under medical supervision.

What it does:

The use of TRAVASOL E / TRAVASOL product is a way to ensure that patients who are unable to eat get an adequate intake of energy, nitrogen and other nutrients, and helps to treat or prevent malnutrition.

When it should not be used:

TRAVASOL E and TRAVASOL products should not be used if:

  • You are allergic to any ingredients (See What the medicinal ingredients are and What the nonmedicinal ingredients are).

  • Your body has problems processing certain amino acids and these amino acids are included in TRAVASOL E / TRAVASOL product.

    • You have liver failure or coma resulting from liver failure.

Also, TRAVASOL E product should not be used if:

  • You have a disorder resulting in high blood levels of substances such as potassium (hyperkalemia), calcium ( hypercalcemia), phosphorus (hyperphosphatemia), sodium (hypernatremia) and magnesium (hypermagnesemia).
  • You are receiving calcium-containing intravenous solutions.
  • You have kidney failure and are not on dialysis.

What the medicinal ingredients are in 1000 mL):

Ingredients (g)Travasol ETravasol (Blend B)Travasol (Blend C)
L alanine L-arginine Glycine L-histidine L-isoleucine L leucine L lysine hydrochloride L-methionine L-phenylalanine L-proline L-Serine L-threonine L tryptophan L-tyrosine L-valine Electrolytes Sodium chloride Sodium acetate trihydrate Dibasic potassium phosphate Magnesium chloride hexahydrate20.8 10.4 20.8 4.4 4.8 6.2 5.8 5.8 6.2 4.2 - 4.2 1.8 0.4 4.6 1.17 6.8 5.22 1.0220.8 10.4 20.8 4.4 4.8 6.2 5.8 5.8 6.2 4.2 - 4.2 1.8 0.4 4.6 - - - -20.7 11.5 10.3 4.8 6 7.3 5.8 4 5.6 6.8 5 4.2 1.8 0.4 5.8 - - - -

What the nonmedicinal ingredients are:

Glacial acetic acid (for pH adjustment), Nitrogen and Water for injection.

What dosage forms it comes in:

TRAVASOL E / TRAVASOL product is a solution for infusion (into the vein). It is supplied in a bag.

The 10% amino acids solution provides a different amount of amino acids and, with some formulations, electrolytes so that your healthcare professional can tailor the infusion to your particular needs.

WARNINGS AND PRECAUTIONS

BEFORE you use TRAVASOL E (amino acids WITH electrolytes injection) or TRAVASOL (amino acids injection), talk to your healthcare professional if:

  • You are allergic to any ingredients. (See What the medicinal ingredients are and What the nonmedicinal ingredients are).
  • You suffer from metabolic acidosis (when the blood is excessively acid)
  • You have kidney or liver problems
  • You are taking any other medicines on a regular basis.

  • You are pregnant or intend to become pregnant

  • You are breastfeeding or intend to breastfeed
  • You have pulmonary edema (collection of fluid into the lung tissue)
  • You have heart failure
  • You have fluid overload (too much water in your body)

In all cases, your healthcare professional will base his/her decision to treat you or your child on factors such as age, weight and clinical condition, together with the results of any tests. Always be sure to check with your healthcare professional if anything about your condition changes.

In newborns and infants, your healthcare professional will measure blood ammonia frequently to check for the presence of a congenital abnormality of amino acid metabolism.

Your healthcare professional will need to monitor how you are doing while you are on this intravenous nutritive supplement. This means that you will need to have laboratory tests done on a routine basis.

INTERACTIONS WITH THIS MEDICATION

No drug interaction studies have been done with TRAVASOL E (amino acids WITH electrolytes injection) or TRAVASOL (amino acids injection).

TRAVASOL E / TRAVASOL product must NOT be administered simultaneously with blood through the same infusion tubing.

Let your healthcare professional know if you are receiving corticosteroids or corticotropin.

There may be interactions between the nutrients in TRAVASOL E / TRAVASOL product and one or more of your medications, for example diuretics, blood pressure drugs, or drugs used to suppress your immune system. You should review your medications with your healthcare professional.

PROPER USE OF THIS MEDICATION

Usual dose:

TRAVASOL E / TRAVASOL products are in pharmacy bulk package and are not for direct infusion. Your healthcare professional will reconstitute the products so they can be administered safely.

Your healthcare professional will select the best TRAVASOL E (amino acids WITH electrolytes injection) or TRAVASOL (amino acids injection) product for you, based on your age and body weight. Your healthcare professional will ensure that you are getting sufficient calories so that the amino acids from TRAVASOL E / TRAVASOL product will be absorbed. Your healthcare professional will also specify a flow rate corresponding to your needs and medical condition.

Overdose:

If your dose is too high or is infused too quickly, the amino acid content may make your blood too acidic. Giving too high a volume may cause fluid overload.

To prevent these events occurring, your healthcare professional will regularly monitor your condition and test your blood and urine parameters.

In case you feel you have been administered too much TRAVASOL E / TRAVASOL product, contact your healthcare practitioner (e.g. healthcare professional), hospital emergency department or the regional poison control centre, even if there are no symptoms.

Missed Dose:

If you feel a dose has been missed contact your attending healthcare professional.

SIDE EFFECTS AND WHAT TO DO

ABOUT THEM

If you notice any changes in the way you feel during or after the treatment, tell your healthcare professional or another member of your medical team immediately.

The tests your healthcare professional will perform while you are taking the intravenous nutritive supplement should reduce the risk of side effects.

If any symptoms of an allergic reaction develop, such as fever or chills, shivering, skin rashes, severe headache or breathing difficulties, contact your attending healthcare professional immediately.

Other side effects may include rapid heart beat, sweating, nausea, vomiting, abdominal swelling, pain on the right side of your belly area (liver).

If any side effect gets serious, or if you notice any side effect not listed in this leaflet, please tell your healthcare professional or a member of your medical team right away.

Occasional reddening and stinging may occur at the point where the tubing enters the body. If this occurs, tell your healthcare professional or nurse immediately.

SERIOUS SIDE EFFECTS, HOW OFTEN THEY HAPPEN AND WHAT TO DO ABOUT THEM
Symptom / effectTalk with your healthcare professionalStop the infusion and contact your doctor (or healthcare professional)
Only if severeIn all cases
UncommonAllergic reactions with symptoms such as fever or chills, shivering, skin rashes, breathing difficulties, severe headache√

This is not a complete list of side effects. For any unexpected effects while taking TRAVASOL E (amino acids WITH electrolytes injection) or TRAVASOL (amino acids injection), contact your healthcare professional.

HOW TO STORE IT

The heatlhcare professional will store the TRAVASOL E / TRAVASOL product at temperatures between 15°C and 25°C, protected from light and kept from freezing.

MORE INFORMATION

This document plus the full product monograph, prepared for health professionals can be obtained by contacting the sponsor, Baxter Corporation, at 1-888-719-9955.

Baxter, Travasol and Viaflex are registered trademarks of Baxter International Inc.

Last revised: April 1, 2020

Reporting Side Effects

You can report any suspected side effects associated with the use of health products to Health Canada by:

  • Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada/adverse-reaction-reporting.html) for information on how to report online, by mail or by fax; or
  • Calling toll-free at 1-866-234-2345

NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.

N N O T E : S h o u l d y o u r e q u i r e i n f o r m a t i o n r e l a t e d t o

About this document

Source: Health Canada – Drug Product Database (DPD) and product monographs · DIN (Drug Identification Number): 00872296

Revision date stated in the text: April 1, 2020

Found a mistake? Write to us via the contact page.

The information on this site does not replace the advice of a doctor or pharmacist.

Drug information for Travasol

DIN 00872296, 00285528, 00388769
Schedule(s) ETHICAL
Active ingredient(s) Leucine, Phenylalanine, Methionine, L-lysine (L-lysine hydrochloride), Isoleucine, Valine, Histidine, Threonine, Tryptophan, L-alanine, Glycine, Arginine, Proline, Tyrosine, Serine
Dosage form(s) Solution
Route(s) of administration Intravenous
Drug class (WHO ATC)
  1. B Blood and blood forming organ drugs
    1. B05 Blood substitutes and perfusion solutions
      1. B05B IV solutions used in parenteral administration of fluids, electrolytes and nutrients
        1. B05BA Solutions for parenteral nutrition
          1. B05BA01 Amino acids
Company BAXTER CORPORATION
Strengths and forms
DIN Strength Dosage form(s) Current status
00872296 730 MG / 560 MG / 400 MG / 580 MG / 600 MG / 580 MG / 480 MG / 420 MG / 180 MG / 2.07 G / 1.03 G / 1.15 G / 680 MG / 40 MG / 500 MG Solution Marketed October 16, 2013
00285528 620 MG / 620 MG / 580 MG / 580 MG / 480 MG / 460 MG / 440 MG / 420 MG / 180 MG / 2.08 G / 2.08 G / 1.04 G / 420 MG / 40 MG / 680 MG / 522 MG / 117 MG / 102 MG Solution Cancelled Post Market October 19, 2017
00388769 620 MG / 620 MG / 580 MG / 580 MG / 480 MG / 460 MG / 440 MG / 420 MG / 180 MG / 2.08 G / 2.08 G / 1.04 G / 420 MG / 40 MG Solution Cancelled Post Market August 11, 2016

Source: Health Canada – Drug Product Database (DPD) and product monographs, data as of November 1, 2026. Data from the Health Canada Drug Product Database, as published there. Not a substitute for the advice of a doctor or pharmacist.