Jascayd: Uses, Side Effects and Dosage

What JASCAYD is used for:

• to treat adults with a lung disease called Idiopathic Pulmonary Fibrosis (IPF).
• to treat adults with a lung disease called Progressive Pulmonary Fibrosis (PPF).

IPF and PPF are conditions in which the tissue in your lungs becomes thickened, stiff and scarred over time. As a result, scarring reduces the ability to transfer oxygen from the lungs into the bloodstream and it becomes difficult to breathe deeply.

How JASCAYD works:

JASCAYD belongs to a group of medicines called phosphodiesterase 4B inhibitors. It regulates the activity of your immune system and reduces tissue scarring in your lungs. This slows the loss of lung function and helps maintain your ability to breathe.

The ingredients in JASCAYD are:

Medicinal ingredient(s): nerandomilast

Non-medicinal ingredients: Croscarmellose sodium, hydroxypropylcellulose, hypromellose 2910, iron oxide black (18 mg tablets only), iron oxide red (18 mg tablets only), iron oxide yellow (9 mg tablets only), lactose monohydrate, macrogol 8000, magnesium stearate, mannitol, microcrystalline cellulose, talc

JASCAYD comes in the following dosage form(s):

Tablets; 9 mg and 18 mg

Do not use JASCAYD if:

• you are allergic to nerandomilast or any of the other ingredients of this medicine

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take JASCAYD. Talk about any health conditions or problems you may have, including if you:

• have one of the following rare genetic conditions because JASCAYD contains lactose:

  • Galactose intolerance
  • Lapp lactase deficiency
  • Glucose-galactose malabsorption

• are pregnant or plan to become pregnant. JASCAYD may cause loss of your pregnancy (miscarriage). It is not known if JASCAYD can harm your unborn baby. Tell your healthcare professional right away if you become pregnant or think you are pregnant while taking JASCAYD.

• are breastfeeding or plan to breastfeed. It is not known if JASCAYD passes into breastmilk. You and your healthcare professional should decide if you will take JASCAYD or breastfeed.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

The following may interact with JASCAYD:

• Clarithromycin, an antibiotic medicine to treat bacterial infections
• Itraconazole, a medicine to treat fungal infections
• Pirfenidone, another medicine used to treat Idiopathic Pulmonary Fibrosis
• Ritonavir, a medicine to treat HIV infections

How to take JASCAYD:

• Always take this medicine exactly as your healthcare professional has told you. Check with your healthcare professional if you are not sure.

• JASCAYD can be taken with or without food.

• Swallow the tablets whole, with water.

• If you cannot swallow tablets whole, the tablet can be dissolved in water:

  • Place about 100 mL of non-carbonated, room temperature water in a glass. Only use water.
  • Drop the tablet in the water without crushing it.
  • Stir regularly for approximately 15 to 20 minutes, until the tablet is in very small pieces (the tablet will not completely dissolve in the water).
  • Drink the JASCAYD and water mixture within 2 hours of mixing.
  • If you do not drink the mixture right away, stir the mixture again before drinking.
  • Rinse the glass with about 100 mL of water and drink it, this ensures you get the full dose.

Usual dose:

The usual dose of JASCAYD is 18 mg twice daily, taken approximately 12 hours apart.

Your healthcare professional will tell you how much JASCAYD to take and when to take it. They will look at how well you tolerate JASCAYD and whether you take other medications and take these into consideration when deciding your dose.

Overdose:

Missed dose:

If you forget a dose, skip the missed dose and take your next dose at your regular time. Do not take more than two tablets of 18 mg JASCAYD in one day.

Possible side effects from using JASCAYD:

These are not all the possible side effects you may have when taking JASCAYD. If you experience any side effects not listed here, tell your healthcare professional.

• Dizziness
• Headache
• Fatigue
• Feeling weak
• Diarrhea
• Nausea
• Weight loss
• Decreased appetite
• Back pain

Serious side effects and what to do about them

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

Reporting side effects

Storage:

Store at room temperature (15 to 30°C), in the original package to protect from light.

Keep this medicine out of the reach and sight of children.

Do not use this medicine after the expiry date which is stated on the blister and on the carton after EXP. The expiry date refers to the last day of that month.

Do not throw away any medicines via wastewater. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

If you want more information about JASCAYD:

• Talk to your healthcare professional
• Find the full product monograph that is prepared for healthcare professionals and includes the Patient Medication Information by visiting the Health Canada Drug Product Database website (https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database.html); the manufacturer’s website (www.boehringer-ingelheim.ca); or by calling 1-800-263-5103, extension 84633.

The information in this leaflet is current up to the time of the last authorization date shown below, but more current information may be available from the manufacturer.

Date of Authorization: 2026-10-08

JASCAYD™ is a trademark of Boehringer Ingelheim International GmbH, used under license.