L01B Antimetabolites: drugs and active ingredients

Place in the ATC system

L Antineoplastic and immunomodulating agents 1,069 drugs
1. L01 Antineoplastic agents 616 drugs
  1. L01B Antimetabolites 118 drugs
    1. L01BA Folic acid analogs, antimetabolites 43 drugs
    2. L01BB Purine analogs, antimetabolites antineoplastic 15 drugs
    3. L01BC Pyrimidine analogues, antineoplastic antimetabolites 60 drugs

Active ingredients of the class

Azacitidine 12 drugs
Capecitabine 10 drugs
Cedazuridine 1 drug
Cladribine 3 drugs
Clofarabine 1 drug
Cytarabine 6 drugs
Decitabine 2 drugs
Fludarabine phosphate 6 drugs
Fludarabine phosphate (fludarabine phosphate sodium) 1 drug
Fluorouracil 8 drugs
Fluorouracil (fluorouracil sodium) 1 drug
Gemcitabine (gemcitabine hydrochloride) 20 drugs
Mercaptopurine 2 drugs
Methotrexate 5 drugs
Methotrexate (methotrexate disodium) 7 drugs
Methotrexate (methotrexate sodium) 14 drugs
Nelarabine 1 drug
Pemetrexed (pemetrexed disodium) 8 drugs
Pemetrexed (pemetrexed disodium hemipentahydrate) 7 drugs
Pralatrexate 1 drug
Raltitrexed 1 drug
Salicylic acid 1 drug
Thioguanine 1 drug
Tipiracil (tipiracil hydrochloride) 1 drug
Trifluridine 1 drug

Drugs in the class and its subclasses

Drug	Rx or OTC
ACH-Capecitabine PM (L01BC06 Capecitabine)	prescription (Rx)
ACH-Methotrexate PM (L01BA01 Methotrexate)	prescription (Rx)
Act Gemcitabine (Actavis Pharma, 200 mg, 1 G) PM (L01BC05 Gemcitabine)	prescription (Rx)
Act Gemcitabine (Actavis Pharma, 38 mg) PM (L01BC05 Gemcitabine)	prescription (Rx)
Act Pemetrexed (L01BA04 Pemetrexed)	prescription (Rx)
Actikerall PM (L01BC52 Fluorouracil, combinations)	prescription (Rx)
Adrucil PM (L01BC02 Fluorouracil)	prescription (Rx)
AJ-Cytarabine PM (L01BC01 Cytarabine)	prescription (Rx)
AJ-Fludarabine PM (L01BB05 Fludarabine)	prescription (Rx)
AJ-Gemcitabine PM (L01BC05 Gemcitabine)	prescription (Rx)
Alimta PM (L01BA04 Pemetrexed)	prescription (Rx)
Apo-Capecitabine PM (L01BC06 Capecitabine)	prescription (Rx)
Apo-Methotrexate PM (L01BA01 Methotrexate)	prescription (Rx)
Atriance PM (L01BB07 Nelarabine)	prescription (Rx)
Auro-Methotrexate Tablets PM (L01BA01 Methotrexate)	prescription (Rx)
Azacitidine for Injection (Apotex) PM (L01BC07 Azacitidine)	prescription (Rx)
Azacitidine for Injection (DR Reddy's Laboratories) PM (L01BC07 Azacitidine)	prescription (Rx)
Azacitidine for Injection (Fresenius Kabi Canada) (L01BC07 Azacitidine)	prescription (Rx)
Azacitidine for Injection (Hikma Canada) PM (L01BC07 Azacitidine)	prescription (Rx)
Azacitidine for Injection (Jamp Pharma) (L01BC07 Azacitidine)	prescription (Rx)
Azacitidine for Injection (MSN Labs Canada) PM (L01BC07 Azacitidine)	prescription (Rx)
Azacitidine for Injection (Sandoz Canada) (L01BC07 Azacitidine)	prescription (Rx)
Capecitabine (Jamp Pharma) PM (L01BC06 Capecitabine)	prescription (Rx)
Capecitabine (Sanis Health) PM (L01BC06 Capecitabine)	prescription (Rx)
Capecitabine (Sivem Pharmaceuticals) PM (L01BC06 Capecitabine)	prescription (Rx)
Cladribine Injection (Fresenius Kabi Canada) PM (L01BB04 Cladribine)	prescription (Rx)
Cladribine Injection (Generic Medical Partners) PM (L01BB04 Cladribine)	prescription (Rx)
Clolar PM (L01BB06 Clofarabine)	prescription (Rx)
Cytarabine Injection (Pfizer Canada) PM (L01BC01 Cytarabine)	prescription (Rx)
Cytarabine Injection (Sterimax) PM (L01BC01 Cytarabine)	prescription (Rx)
Cytarabine Injection BP PM (L01BC01 Cytarabine)	prescription (Rx)
Cytosar PM (L01BC01 Cytarabine)	prescription (Rx)
Demylocan PM (L01BC08 Decitabine)	prescription (Rx)
Efudex PM (L01BC02 Fluorouracil)	prescription (Rx)
Eugia-Methotrexate PM (L01BA01 Methotrexate)	prescription (Rx)
Fludara (Sanofi Genzyme, A Division of Sanofi-Aventis Canada) PM (L01BB05 Fludarabine)	prescription (Rx)
Fludara (Sanofi-Aventis Canada) (L01BB05 Fludarabine)	prescription (Rx)
Fludarabine Phosphate for Injection (Fresenius Kabi Canada) PM (L01BB05 Fludarabine)	prescription (Rx)
Fludarabine Phosphate for Injection (Teva Canada) (L01BB05 Fludarabine)	prescription (Rx)
Fludarabine Phosphate Injection (Mylan Pharmaceuticals) PM (L01BB05 Fludarabine)	prescription (Rx)
Fludarabine Phosphate Injection (Omega Laboratories) PM (L01BB05 Fludarabine)	prescription (Rx)
Fluorouracil Injection (Biolyse Pharma) PM (L01BC02 Fluorouracil)	prescription (Rx)
Fluorouracil Injection (Generic Medical Partners) (L01BC02 Fluorouracil)	prescription (Rx)
Fluorouracil Injection (Sandoz Canada) PM (L01BC02 Fluorouracil)	prescription (Rx)
Fluorouracil Injection USP (Accord Healthcare) PM (L01BC02 Fluorouracil)	prescription (Rx)
Fluorouracil Injection USP (Pfizer Canada) PM (L01BC02 Fluorouracil)	prescription (Rx)
Folotyn (L01BA05 Pralatrexate%)	prescription (Rx)
Gemcitabine for Injection (Accord Healthcare, 1 G, 2 G) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine for Injection (Accord Healthcare, 200 mg) (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine for Injection (Fresenius Kabi Canada) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine for Injection (Teva Canada) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine for Injection Concentrate PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine for Injection USP PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine for Injection, USP (DR Reddy's Laboratories) (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine for Injection, USP (Hospira Healthcare) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine for Injection, USP (Mylan Pharmaceuticals) (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine Hydrochloride for Injection PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine Injection (Apotex) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine Injection (Hikma Canada) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine Injection (Juno Pharmaceuticals) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine Injection (Pfizer Canada) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine Injection (Sandoz Canada) PM (L01BC05 Gemcitabine)	prescription (Rx)
Gemcitabine Sun for Injection (L01BC05 Gemcitabine)	prescription (Rx)
Gemzar (200mg/Vial) (L01BC05 Gemcitabine)	prescription (Rx)
Inqovi PM (L01BC58 Decitabine, combinations)	prescription (Rx)
Jamp Methotrexate PM (L01BA01 Methotrexate)	prescription (Rx)
Jamp Methotrexate Tablets PM (L01BA01 Methotrexate)	prescription (Rx)
Jamp-Methotrexate (L01BA01 Methotrexate)	prescription (Rx)
Lanvis PM (L01BB03 Tioguanine)	prescription (Rx)
Leustatin 1mg/mL (L01BB04 Cladribine)	prescription (Rx)
Lonsurf PM (L01BC59 Trifluridine, combinations)	prescription (Rx)
M-Methotrexate PM (L01BA01 Methotrexate)	prescription (Rx)
Mercaptopurine Tablets USP PM (L01BB02 Mercaptopurine)	prescription (Rx)
Methotrexate PM (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Injection BP (Accord Healthcare) (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Injection BP (Uman Pharma) PM (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Injection USP (Pfizer Canada) (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Injection USP (Sandoz Canada) PM (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Injection, BP PM (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Injection, USP PM (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Pf/Sa Injection PM (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Sodium Injection (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Sodium Injection USP PM (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Tablets, USP (Pfizer Canada, PM 00081660) PM (L01BA01 Methotrexate)	prescription (Rx)
Methotrexate Tablets, USP (Pfizer Canada, PM 00082684) PM (L01BA01 Methotrexate)	prescription (Rx)
Metoject (Medexus Pharmaceuticals, 10 mg) PM (L01BA01 Methotrexate)	prescription (Rx)
Metoject (Medexus Pharmaceuticals, 20 mg) PM (L01BA01 Methotrexate)	prescription (Rx)
Metoject (Medexus Pharmaceuticals, 7.5 mg) PM (L01BA01 Methotrexate)	prescription (Rx)
Mint-Capecitabine PM (L01BC06 Capecitabine)	prescription (Rx)
Nat-Azacitidine (L01BC07 Azacitidine)	prescription (Rx)
Onureg PM (L01BC07 Azacitidine)	prescription (Rx)
Pemetrexed Disodium for Injection (Accord Healthcare) PM (L01BA04 Pemetrexed)	prescription (Rx)
Pemetrexed Disodium for Injection (Auro Pharma) PM (L01BA04 Pemetrexed)	prescription (Rx)
Pemetrexed Disodium for Injection (Eugia Pharma) (L01BA04 Pemetrexed)	prescription (Rx)
Pemetrexed Disodium for Injection (Hikma Canada) (L01BA04 Pemetrexed)	prescription (Rx)
Pemetrexed Disodium for Injection (Jamp Pharma) (L01BA04 Pemetrexed)	prescription (Rx)
Pemetrexed Disodium for Injection (Marcan Pharmaceuticals) (L01BA04 Pemetrexed)	prescription (Rx)
Pemetrexed Disodium for Injection (Mylan Pharmaceuticals) (L01BA04 Pemetrexed)	prescription (Rx)
Pemetrexed Disodium for Injection (Pfizer Canada) PM (L01BA04 Pemetrexed)	prescription (Rx)
Pemetrexed Disodium for Injection (Sandoz Canada) PM (L01BA04 Pemetrexed)	prescription (Rx)

Other classes of the same level

L01A Alkylating agents 61 drugs
L01C Plant alkaloids and other natural products, antineoplastic drugs 75 drugs
L01D Cytotoxic antibiotics and related substances 49 drugs
L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 118 drugs
L01X Other antineoplastic agents 120 drugs

Other names of the drug class

Czech: L01B Antimetabolity
English (United Kingdom): L01B Antimetabolites
French: L01B antimétabolites
German: L01B Antimetaboliten
Spanish: L01B Antimetabolitos (antineoplasicos)
German (Austria): L01B ANTIMETABOLITEN
Italian: L01B ANTIMETABOLITI
Polish: L01B Antymetabolity
Turkish: L01B ANTİMETABOLİTLER
Portuguese (Brazil): L01B ANTIMETABOLITOS
Slovak: L01B Antimetabolity
German (Switzerland): L01B Antimetaboliten
French (Switzerland): L01B Antimétabolites
Italian (Switzerland): L01B Antimetaboliti
Dutch: L01B Antimetabolieten

Sources

Patient medication information and product monographs: Health Canada, Drug Product Database
Active ingredients, ATC codes and Rx or OTC status: Health Canada, Drug Product Database
World Health Organization (WHO): ATC/DDD system, class L01B

Ask your doctor or pharmacist for advice.