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L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents

ATC class of level 3 – pharmacological subgroup

This page lists the patient medication information or the product monograph for 118 drugs in this drug class and its subclasses.

Place in the ATC system

  1. L Antineoplastic and immunomodulating agents 1,069 drugs
    1. L01 Antineoplastic agents 616 drugs
      1. L01E Protein kinase inhibitors, antineoplastic and immunomodulating agents 118 drugs
        1. L01EA BCR-ABL tyrosine kinase inhibitors 30 drugs
        2. L01EB Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors 16 drugs
        3. L01EC B-Raf serine-threonine kinase (BRAF) inhibitors 3 drugs
        4. L01ED Anaplastic lymphoma kinase (ALK) inhibitors 4 drugs
        5. L01EE Mitogen-activated protein kinase (MEK) inhibitors 5 drugs
        6. L01EF Cyclin-dependent kinase (CDK) inhibitors 7 drugs
        7. L01EG Mammalian target of rapamycin (mTOR) kinase inhibitors 1 drug
        8. L01EH Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors 5 drugs
        9. L01EJ Janus-associated kinase (JAK) inhibitors 3 drugs
        10. L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors 3 drugs
        11. L01EL Bruton's tyrosine kinase (BTK) inhibitors 4 drugs
        12. L01EM Phosphatidylinositol-3-kinase (Pi3K) inhibitors 3 drugs
        13. L01EX Other protein kinase inhibitors 30 drugs

Active ingredients of the class

Drugs in the class and its subclasses

DrugRx or OTC
ACH-Imatinib PM (L01EA01 Imatinib) prescription (Rx)
Alecensaro PM (L01ED03 Alectinib) prescription (Rx)
Apo-Dasatinib PM (L01EA02 Dasatinib) prescription (Rx)
Apo-Dasatinib Tablets PM (L01EA02 Dasatinib) prescription (Rx)
Apo-Erlotinib PM (L01EB02 Erlotinib) prescription (Rx)
Apo-Gefitinib PM (L01EB01 Gefitinib) prescription (Rx)
Apo-Imatinib PM (L01EA01 Imatinib) prescription (Rx)
Apo-Sorafenib PM (L01EX02 Sorafenib) prescription (Rx)
Augtyro (L01EX28 Repotrectinib) prescription (Rx)
Auro-Gefitinib (L01EB01 Gefitinib) prescription (Rx)
Auro-Nintedanib PM (L01EX09 Nintedanib) prescription (Rx)
Auro-Pazopanib (L01EX03 Pazopanib) prescription (Rx)
Ayvakyt PM (L01EX18 Avapritinib) prescription (Rx)
Balversa PM (L01EN01 Erdafitinib) prescription (Rx)
Bosulif (Pfizer Canada, 100 mg, 500 mg) PM (L01EA04 Bosutinib) prescription (Rx)
Bosulif (Pfizer Canada, 400 mg) PM (L01EA04 Bosutinib) prescription (Rx)
Braftovi PM (L01EC03 Encorafenib) prescription (Rx)
Brukinsa PM (L01EL03 Zanubrutinib) prescription (Rx)
Cabometyx (L01EX07 Cabozantinib) prescription (Rx)
Calquence (Astrazeneca Canada, Capsule) PM (L01EL02 Acalabrutinib) prescription (Rx)
Calquence (Astrazeneca Canada, Tablet) PM (L01EL02 Acalabrutinib) prescription (Rx)
Cotellic PM (L01EE02 Cobimetinib) prescription (Rx)
Eugia-Gefitinib (L01EB01 Gefitinib) prescription (Rx)
Eugia-Nintedanib PM (L01EX09 Nintedanib) prescription (Rx)
Eugia-Sunitinib PM (L01EX01 Sunitinib) prescription (Rx)
Fruzaqla (L01EK04 Fruquintinib) prescription (Rx)
Gavreto PM (L01EX23 Pralsetinib) prescription (Rx)
GD-Temsirolimus PM (L01EG01 Temsirolimus) prescription (Rx)
Giotrif PM (L01EB03 Afatinib) prescription (Rx)
Gleevec (Novartis Pharmaceuticals Canada, 100 mg, 400 mg) PM (L01EA01 Imatinib) prescription (Rx)
Gleevec (Novartis Pharmaceuticals Canada, 100 mg) (L01EA01 Imatinib) prescription (Rx)
GLN-Nintedanib PM (L01EX09 Nintedanib) prescription (Rx)
Hernexeos PM (L01EH04 Zongertinib) prescription (Rx)
Hyrnuo (L01EH06 Sevabertinib) prescription (Rx)
Ibrance (Pfizer Canada, Capsule) (L01EF01 Palbociclib) prescription (Rx)
Ibrance (Pfizer Canada, Tablet) PM (L01EF01 Palbociclib) prescription (Rx)
Iclusig PM (L01EA05 Ponatinib) prescription (Rx)
Imatinib (Sanis Health) PM (L01EA01 Imatinib) prescription (Rx)
Imatinib (Sivem Pharmaceuticals) PM (L01EA01 Imatinib) prescription (Rx)
Inlyta (Pfizer Canada, 1 mg, 5 mg) (L01EK01 Axitinib) prescription (Rx)
Inlyta (Pfizer Canada, 3 mg, 7 mg) PM (L01EK01 Axitinib) prescription (Rx)
Inrebic (L01EJ02 Fedratinib) prescription (Rx)
Itovebi PM (L01EM06 Inavolisib) prescription (Rx)
Jakavi PM (L01EJ01 Ruxolitinib) prescription (Rx)
Jamp Imatinib PM (L01EA01 Imatinib) prescription (Rx)
Jamp Nintedanib PM (L01EX09 Nintedanib) prescription (Rx)
Jaypirca PM (L01EL05 Pirtobrutinib) prescription (Rx)
Kisqali PM (L01EF02 Ribociclib) prescription (Rx)
Koselugo Granules PM (L01EE04 Selumetinib) prescription (Rx)
Lazcluze PM (L01EB09 Lazertinib) prescription (Rx)
Lenvima (L01EX08 Lenvatinib) prescription (Rx)
Lorbrena PM (L01ED05 Lorlatinib) prescription (Rx)
Mar-Afatinib PM (L01EB03 Afatinib) prescription (Rx)
Mekinist (Novartis Pharmaceuticals Canada, 0.5 mg, 2 mg, 4.7 mg) PM (L01EE01 Trametinib) prescription (Rx)
Mekinist (Novartis Pharmaceuticals Canada, 1 mg) PM (L01EE01 Trametinib) prescription (Rx)
Mektovi PM (L01EE03 Binimetinib) prescription (Rx)
Mint-Imatinib PM (L01EA01 Imatinib) prescription (Rx)
Mylan-Imatinib (L01EA01 Imatinib) prescription (Rx)
Nat-Erlotinib PM (L01EB02 Erlotinib) prescription (Rx)
Nat-Gefitinib (L01EB01 Gefitinib) prescription (Rx)
Nat-Imatinib PM (L01EA01 Imatinib) prescription (Rx)
Nat-Palbociclib PM (L01EF01 Palbociclib) prescription (Rx)
Nat-Sunitinib (L01EX01 Sunitinib) prescription (Rx)
Nerlynx (L01EH02 Neratinib) prescription (Rx)
Nexavar PM (L01EX02 Sorafenib) prescription (Rx)
NRA-Imatinib PM (L01EA01 Imatinib) prescription (Rx)
Ofev PM (L01EX09 Nintedanib) prescription (Rx)
Ojemda PM (L01EC04 Tovorafenib) prescription (Rx)
Ojjaara PM (L01EJ04 Momelotinib) prescription (Rx)
Piqray PM (L01EM03 Alpelisib) prescription (Rx)
PMS-Erlotinib PM (L01EB02 Erlotinib) prescription (Rx)
PMS-Imatinib (L01EA01 Imatinib) prescription (Rx)
PMS-Nilotinib (L01EA03 Nilotinib) prescription (Rx)
PMS-Palbociclib PM (L01EF01 Palbociclib) prescription (Rx)
PMS-Pazopanib (L01EX03 Pazopanib) prescription (Rx)
Qinlock PM (L01EX19 Ripretinib) prescription (Rx)
Reddy-Bosutinib PM (L01EA04 Bosutinib) prescription (Rx)
Reddy-Dasatinib PM (L01EA02 Dasatinib) prescription (Rx)
Reddy-Nilotinib (L01EA03 Nilotinib) prescription (Rx)
Retevmo PM (L01EX22 Selpercatinib) prescription (Rx)
Rozlytrek PM (L01EX14 Entrectinib) prescription (Rx)
Rydapt (L01EX10 Midostaurin) prescription (Rx)
Sandoz Afatinib (L01EB03 Afatinib) prescription (Rx)
Sandoz Imatinib PM (L01EA01 Imatinib) prescription (Rx)
Sandoz Pazopanib (L01EX03 Pazopanib) prescription (Rx)
Scemblix PM (L01EA06 Asciminib) prescription (Rx)
Sprycel PM (L01EA02 Dasatinib) prescription (Rx)
Stivarga PM (L01EX05 Regorafenib) prescription (Rx)
Sutent (L01EX01 Sunitinib) prescription (Rx)
Tabrecta (L01EP01 Capmatinib) prescription (Rx)
Tafinlar PM (L01EC02 Dabrafenib) prescription (Rx)
Tagrisso (L01EB04 Osimertinib) prescription (Rx)
Tarceva (L01EB02 Erlotinib) prescription (Rx)
Taro-Dasatinib (L01EA02 Dasatinib) prescription (Rx)
Taro-Imatinib PM (L01EA01 Imatinib) prescription (Rx)
Taro-Palbociclib PM (L01EF01 Palbociclib) prescription (Rx)
Taro-Sunitinib (L01EX01 Sunitinib) prescription (Rx)
Tasigna (Novartis Pharmaceuticals Canada, 200 mg, 150 mg) PM (L01EA03 Nilotinib) prescription (Rx)
Tasigna (Novartis Pharmaceuticals Canada, 50 mg) PM (L01EA03 Nilotinib) prescription (Rx)
Tepmetko PM (L01EP02 Tepotinib) prescription (Rx)

Other classes of the same level

Other names of the drug class

Sources

  • Patient medication information and product monographs: Health Canada, Drug Product Database
  • Active ingredients, ATC codes and Rx or OTC status: Health Canada, Drug Product Database
  • World Health Organization (WHO): ATC/DDD system, class L01E

Ask your doctor or pharmacist for advice.